about
Induction of resistance to azole drugs in Trypanosoma cruzi.Linear amplicons as precursors of amplified circles in methotrexate-resistant Leishmania tarentolaeFormation of extrachromosomal circular amplicons with direct or inverted duplications in drug-resistant Leishmania tarentolaeFormation of linear inverted repeat amplicons following targeting of an essential gene in Leishmania.Drug resistance analysis by next generation sequencing in LeishmaniaPlasticity of the Leishmania genome leading to gene copy number variations and drug resistanceEfficacy of the herbicide trifluralin against four P-glycoprotein-expressing strains of LeishmaniaA genetically hard-wired metabolic transcriptome in Plasmodium falciparum fails to mount protective responses to lethal antifolatesRetention and loss of RNA interference pathways in trypanosomatid protozoansGene expression profiling and molecular characterization of antimony resistance in Leishmania amazonensisMultiple mutations in heterogeneous miltefosine-resistant Leishmania major population as determined by whole genome sequencingGeneration of Leishmania hybrids by whole genomic DNA transformationAsexual populations of the human malaria parasite, Plasmodium falciparum, use a two-step genomic strategy to acquire accurate, beneficial DNA amplificationsFormation of linear amplicons with inverted duplications in Leishmania requires the MRE11 nucleaseOver-Expression of Cysteine Leucine Rich Protein Is Related to SAG Resistance in Clinical Isolates of Leishmania donovaniIsolation of genes mediating resistance to inhibitors of nucleoside and ergosterol metabolism in Leishmania by overexpression/selection.Differential protein expression analysis of Leishmania major reveals novel roles for methionine adenosyltransferase and S-adenosylmethionine in methotrexate resistance.The SIDER2 elements, interspersed repeated sequences that populate the Leishmania genomes, constitute subfamilies showing chromosomal proximity relationship.Antimony transport mechanisms in resistant leishmania parasites.Functional compartmentalization of Rad9 and Hus1 reveals diverse assembly of the 9-1-1 complex components during the DNA damage response in Leishmania.Effect of large targeted deletions on the mitotic stability of an extra chromosome mediating drug resistance in Leishmania.Frequency of drug resistance gene amplification in clinical leishmania strainsHeterogeneity of molecular resistance patterns in antimony-resistant field isolates of Leishmania species from the western Mediterranean area.The roles of pteridine reductase 1 and dihydrofolate reductase-thymidylate synthase in pteridine metabolism in the protozoan parasite Leishmania major.Non-Mendelian inheritance induced by gene amplification in the germ nucleus of Paramecium tetraurelia.Protozomics: trypanosomatid parasite genetics comes of age.Gene amplification and point mutations in pyrimidine metabolic genes in 5-fluorouracil resistant Leishmania infantum.The endosymbiont (Buchnera sp.) of the aphid Diuraphis noxia contains plasmids consisting of trpEG and tandem repeats of trpEG pseudogenes.Increased expression of LD1 genes transcribed by RNA polymerase I in Leishmania donovani as a result of duplication into the rRNA gene locus.Leishmaniases of the New World: current concepts and implications for future researchUnstable amplification of two extrachromosomal elements in alpha-difluoromethylornithine-resistant Leishmania donovani.Leishmania donovani ornithine decarboxylase is indispensable for parasite survival in the mammalian host.Formation of new chromosomes as a virulence mechanism in yeast Candida glabrata.Targeting the Cytochrome bc1 Complex of Leishmania Parasites for Discovery of Novel Drugs.Amplification of an alternate transporter gene suppresses the avirulent phenotype of glucose transporter null mutants in Leishmania mexicana.Molecular characterization of the MRPA transporter and antimony uptake in four New World Leishmania spp. susceptible and resistant to antimony.Folate metabolic pathways in LeishmaniaRole of the ABC transporter MRPA (PGPA) in antimony resistance in Leishmania infantum axenic and intracellular amastigotes.Gene expression modulation is associated with gene amplification, supernumerary chromosomes and chromosome loss in antimony-resistant Leishmania infantum.Intrachromosomal tandem duplication and repeat expansion during attempts to inactivate the subtelomeric essential gene GSH1 in Leishmania
P2860
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P2860
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Gene amplification in Leishmania.
@en
type
label
Gene amplification in Leishmania.
@en
prefLabel
Gene amplification in Leishmania.
@en
P1476
Gene amplification in Leishmania.
@en
P2093
Beverley SM
P304
P356
10.1146/ANNUREV.MI.45.100191.002221
P577
1991-01-01T00:00:00Z