Proteasome inhibitor PS-341 (VELCADE) induces stabilization of the TRAIL receptor DR5 mRNA through the 3'-untranslated region.
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Noxa/Bcl-2 protein interactions contribute to bortezomib resistance in human lymphoid cellsTrailing TRAIL Resistance: Novel Targets for TRAIL Sensitization in Cancer CellsBortezomib sensitizes human renal cell carcinomas to TRAIL apoptosis through increased activation of caspase-8 in the death-inducing signaling complex.Utilization of the cellular stress response to sensitize cancer cells to TRAIL-mediated apoptosis.Deletion of Chromosomal Region 8p21 Confers Resistance to Bortezomib and Is Associated with Upregulated Decoy TRAIL Receptor Expression in Patients with Multiple Myeloma.HuR's post-transcriptional regulation of Death Receptor 5 in pancreatic cancer cells.Proteasome inhibition and allogeneic hematopoietic stem cell transplantation: a reviewTumor Necrosis Factor-related apoptosis-inducing ligand (TRAIL) Receptor-1 and Receptor-2 agonists for cancer therapy.Naturally occurring, tumor-specific, therapeutic proteins.Targeting the extrinsic apoptosis signaling pathway for cancer therapy.Immunomodulation using agonists and antagonists: potential clinical applications.Apoptosis-modulating drugs for improved cancer therapy.The three Rs along the TRAIL: resistance, re-sensitization and reactive oxygen species (ROS).Regulation of TRAIL-receptor expression by the ubiquitin-proteasome system.Chloroquine enhances TRAIL-mediated apoptosis through up-regulation of DR5 by stabilization of mRNA and protein in cancer cells.Intracellular localization of DR5 and related regulatory pathways as a mechanism of resistance to TRAIL in cancer.Rapid proteasomal degradation of posttranscriptional regulators of the TIS11/tristetraprolin family is induced by an intrinsically unstructured region independently of ubiquitination.DAPK2 is a novel modulator of TRAIL-induced apoptosis.Bortezomib reverses the proliferative and antiapoptotic effect of neuropeptides on prostate cancer cells.Novel insights into the synergistic interaction of Bortezomib and TRAIL: tBid provides the link.Quercetin enhances TRAIL-induced apoptosis in prostate cancer cells via increased protein stability of death receptor 5.Bortezomib-induced miRNAs direct epigenetic silencing of locus genes and trigger apoptosis in leukemia.
P2860
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P2860
Proteasome inhibitor PS-341 (VELCADE) induces stabilization of the TRAIL receptor DR5 mRNA through the 3'-untranslated region.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Proteasome inhibitor PS-341 (V ...... gh the 3'-untranslated region.
@en
type
label
Proteasome inhibitor PS-341 (V ...... gh the 3'-untranslated region.
@en
prefLabel
Proteasome inhibitor PS-341 (V ...... gh the 3'-untranslated region.
@en
P2860
P1476
Proteasome inhibitor PS-341 (V ...... gh the 3'-untranslated region.
@en
P2093
Andrew S Kraft
Karthikeyan Kandasamy
P2860
P304
P356
10.1158/1535-7163.MCT-07-2368
P577
2008-05-01T00:00:00Z