Mechanism for alternating access in neurotransmitter transporters.
about
Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion transportMonoamine transporters: insights from molecular dynamics simulationsInsights to ligand binding to the monoamine transporters-from homology modeling to LeuBAT and dDATInverted topologies in membrane proteins: a mini-reviewThe SLC6 transporters: perspectives on structure, functions, regulation, and models for transporter dysfunctionVisualizing functional motions of membrane transporters with molecular dynamics simulationsA steered molecular dynamics study of binding and translocation processes in the GABA transporterSimulating the function of sodium/proton antiportersSubstrate-bound outward-open state of the betaine transporter BetP provides insights into Na+ coupling.Modeling and dynamics of the inward-facing state of a Na+/Cl- dependent neurotransmitter transporter homologueA competitive inhibitor traps LeuT in an open-to-out conformation.Molecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter Mhp1Molecular basis of substrate-induced permeation by an amino acid antiporterInsights into transport mechanism from LeuT engineered to transport tryptophanCrystal structure of a bacterial homologue of the bile acid sodium symporter ASBTX-ray structures of LeuT in substrate-free outward-open and apo inward-open statesStructures of LeuT in bicelles define conformation and substrate binding in a membrane-like contextLigand induced conformational changes of the human serotonin transporter revealed by molecular dynamics simulationsMapping Cholesterol Interaction Sites on Serotonin Transporter through Coarse-Grained Molecular DynamicsExploring the Inhibitory Mechanism of Approved Selective Norepinephrine Reuptake Inhibitors and Reboxetine Enantiomers by Molecular Dynamics StudyStructure alignment of membrane proteins: Accuracy of available tools and a consensus strategyMolecular motions involved in Na-K-Cl cotransporter-mediated ion transport and transporter activation revealed by internal cross-linking between transmembrane domains 10 and 11/12.A conserved salt bridge between transmembrane segments 1 and 10 constitutes an extracellular gate in the dopamine transporterRepeat-swap homology modeling of secondary active transporters: updated protocol and prediction of elevator-type mechanismsInsights from molecular dynamics: the binding site of cocaine in the dopamine transporter and permeation pathways of substrates in the leucine and dopamine transporters.Electrostatics, hydration, and proton transfer dynamics in the membrane domain of respiratory complex IModelling and mutational analysis of Aspergillus nidulans UreA, a member of the subfamily of urea/H⁺ transporters in fungi and plantsStructural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family.Ligand effects on cross-linking support a conformational mechanism for serotonin transport.Binding and orientation of tricyclic antidepressants within the central substrate site of the human serotonin transporter.Conformational dynamics of ligand-dependent alternating access in LeuT.Molecular modeling and ligand docking for solute carrier (SLC) transportersConformational changes in dopamine transporter intracellular regions upon cocaine binding and dopamine translocationThe N terminus of monoamine transporters is a lever required for the action of amphetaminesStructural analysis of the extracellular entrance to the serotonin transporter permeation pathway.Comparison of human solute carriersStructural Symmetry in Membrane Proteins.A conserved methionine residue controls the substrate selectivity of a neuronal glutamate transporter.The ugly side of amphetamines: short- and long-term toxicity of 3,4-methylenedioxymethamphetamine (MDMA, 'Ecstasy'), methamphetamine and D-amphetamine.Unbiased simulations reveal the inward-facing conformation of the human serotonin transporter and Na(+) ion release.
P2860
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P2860
Mechanism for alternating access in neurotransmitter transporters.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Mechanism for alternating access in neurotransmitter transporters.
@en
type
label
Mechanism for alternating access in neurotransmitter transporters.
@en
prefLabel
Mechanism for alternating access in neurotransmitter transporters.
@en
P2093
P2860
P356
P1476
Mechanism for alternating access in neurotransmitter transporters.
@en
P2093
Barry H Honig
Gary Rudnick
Joan Gesmonde
Lucy R Forrest
Miriam T Jacobs
Yuan-Wei Zhang
P2860
P304
10338-10343
P356
10.1073/PNAS.0804659105
P407
P577
2008-07-22T00:00:00Z