ACTH inhibits bTREK-1 K+ channels through multiple cAMP-dependent signaling pathways
about
Role of EPAC in cAMP-Mediated Actions in Adrenocortical CellsMetabolites of an Epac-selective cAMP analog induce cortisol synthesis by adrenocortical cells through a cAMP-independent pathwayAnxiety and depression with neurogenesis defects in exchange protein directly activated by cAMP 2-deficient mice are ameliorated by a selective serotonin reuptake inhibitor, Prozac.cAMP analogs and their metabolites enhance TREK-1 mRNA and K+ current expression in adrenocortical cells.Curcumin inhibits ACTH- and angiotensin II-stimulated cortisol secretion and Ca(v)3.2 currentACTH induces Cav3.2 current and mRNA by cAMP-dependent and cAMP-independent mechanisms.Reciprocal regulation of TREK-1 channels by arachidonic acid and CRH in mouse corticotropesNCI-H295R, a human adrenal cortex-derived cell line, expresses purinergic receptors linked to Ca²⁺-mobilization/influx and cortisol secretion8-Phenylthio-adenines stimulate the expression of steroid hydroxylases, Cav3.2 Ca²⁺ channels, and cortisol synthesis by a cAMP-independent mechanism.Two-pore domain potassium channels in the adrenal cortex.Adrenal fasciculata cells express T-type and rapidly and slowly activating L-type Ca2+ channels that regulate cortisol secretionACTH is a potent regulator of gene expression in human adrenal cells.Ca2+ and K+ channels of normal human adrenal zona fasciculata cells: properties and modulation by ACTH and AngII.Protein kinase A and C regulate leak potassium currents in freshly isolated vascular myocytes from the aorta.N6-substituted cAMP analogs inhibit bTREK-1 K+ channels and stimulate cortisol secretion by a protein kinase A-independent mechanism.Steroidogenesis-adrenal cell signal transduction.Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development.
P2860
Q26744605-9A252530-AA98-4D88-93EA-9E2579D424DCQ28475669-EC731B3D-7E01-47E2-ADDA-105FC122F73FQ30818437-3DA71747-7D38-4DBA-AE88-BE0ECD168AF4Q33714698-71D893CB-71F7-4E17-AC5B-A4B8141C986EQ33783283-B9DF0E15-5CFD-45F0-8121-D05FEFB323BFQ33924353-5A6907F8-8A21-42DF-A7C3-A38E7123FED6Q34788427-EBDABCDF-72A6-45C3-A436-7932422D9085Q34948476-CD45E30A-27F0-44C1-88DC-A6F9ECA34955Q35543621-65145CCF-999D-42F3-9655-48574FEA0160Q35597757-0A26BE3F-B89D-488C-A9D8-2A11AEB09B17Q35671899-AEF9AACD-2C66-4177-872F-0EA2D344C72CQ37051358-A98FE5C1-A8D2-4F9F-A68E-0C0BA321E76AQ37055492-A801652C-463E-48E6-AF03-C2DE75996DAEQ37192384-5F6EE44D-E14C-4710-90CD-79EBF5E803E8Q37444490-5F679E4C-A118-437A-967E-9C83B2DFAFEBQ38221447-479BB73F-F7C8-4163-88DB-B7B1F4874EC9Q52656382-A4AF0F2E-20A8-4F37-B841-35632ADCB5F9
P2860
ACTH inhibits bTREK-1 K+ channels through multiple cAMP-dependent signaling pathways
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
ACTH inhibits bTREK-1 K+ channels through multiple cAMP-dependent signaling pathways
@ast
ACTH inhibits bTREK-1 K+ channels through multiple cAMP-dependent signaling pathways
@en
type
label
ACTH inhibits bTREK-1 K+ channels through multiple cAMP-dependent signaling pathways
@ast
ACTH inhibits bTREK-1 K+ channels through multiple cAMP-dependent signaling pathways
@en
prefLabel
ACTH inhibits bTREK-1 K+ channels through multiple cAMP-dependent signaling pathways
@ast
ACTH inhibits bTREK-1 K+ channels through multiple cAMP-dependent signaling pathways
@en
P2093
P2860
P356
P1476
ACTH inhibits bTREK-1 K+ channels through multiple cAMP-dependent signaling pathways
@en
P2093
Haiyan Liu
John J Enyeart
Judith A Enyeart
P2860
P304
P356
10.1085/JGP.200810003
P577
2008-08-01T00:00:00Z