FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets.
about
Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation in CIDECOverexpression of KLF15 transcription factor in adipocytes of mice results in down-regulation of SCD1 protein expression in adipocytes and consequent enhancement of glucose-induced insulin secretionLipid droplets as fat storage organelles in Caenorhabditis elegans: Thematic Review Series: Lipid Droplet Synthesis and Metabolism: from Yeast to ManCholesterol ester droplets and steroidogenesisTurnover of the actomyosin complex in zebrafish embryos directs geometric remodelling and the recruitment of lipid droplets.A role for phosphatidic acid in the formation of "supersized" lipid dropletsPerilipin1 promotes unilocular lipid droplet formation through the activation of Fsp27 in adipocytesPackaging of fat: an evolving model of lipid droplet assembly and expansionAdipose tissue dysfunction and its effects on tumor metabolismTranscriptome-wide RNA sequencing analysis of rat skeletal muscle feed arteries. I. Impact of obesityBerardinelli-seip congenital lipodystrophy 2/seipin is a cell-autonomous regulator of lipolysis essential for adipocyte differentiationPerilipin 5, a lipid droplet-associated protein, provides physical and metabolic linkage to mitochondriaLong-term live cell microscopy studies of lipid droplet fusion dynamics in adipocytes.The evolutionarily conserved protein CG9186 is associated with lipid droplets, required for their positioning and for fat storage.Role for formin-like 1-dependent acto-myosin assembly in lipid droplet dynamics and lipid storage.Regulation of gene expression by FSP27 in white and brown adipose tissue.Nematode homologue of PQBP1, a mental retardation causative gene, is involved in lipid metabolismAll-trans-retinoic acid ameliorates hepatic steatosis in mice by a novel transcriptional cascade.Increased subcutaneous adipose tissue expression of genes involved in glycerolipid-fatty acid cycling in obese insulin-resistant versus -sensitive individualsAdipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acidsDynamic and differential regulation of proteins that coat lipid droplets in fatty liver dystrophic mice.Fat-specific protein 27 inhibits lipolysis by facilitating the inhibitory effect of transcription factor Egr1 on transcription of adipose triglyceride lipase.Fat-specific protein 27 undergoes ubiquitin-dependent degradation regulated by triacylglycerol synthesis and lipid droplet formation.Perilipin overexpression in white adipose tissue induces a brown fat-like phenotype.Cideb facilitates the lipidation of chylomicrons in the small intestine.CIDE gene expression in adipose tissue, liver, and skeletal muscle from obese and lean pigsDifferential roles of CIDEA and CIDEC in insulin-induced anti-apoptosis and lipid droplet formation in human adipocytes.beta3-adrenergic receptor induction of adipocyte inflammation requires lipolytic activation of stress kinases p38 and JNKThe role of lipid droplets in metabolic disease in rodents and humans.Global mapping of cell type-specific open chromatin by FAIRE-seq reveals the regulatory role of the NFI family in adipocyte differentiation.FSP27 promotes lipid droplet clustering and then fusion to regulate triglyceride accumulation.PPARγ-induced cardiolipotoxicity in mice is ameliorated by PPARα deficiency despite increases in fatty acid oxidation.Identification of the lipid droplet targeting domain of the Cidea proteinDEPTOR cell-autonomously promotes adipogenesis, and its expression is associated with obesity.Nuclear orphan receptor TAK1/TR4-deficient mice are protected against obesity-linked inflammation, hepatic steatosis, and insulin resistance.Chronic glucocorticoid exposure-induced epididymal adiposity is associated with mitochondrial dysfunction in white adipose tissue of male C57BL/6J mice.Regulation of fat specific protein 27 by isoproterenol and TNF-α to control lipolysis in murine adipocytes.Not just fat: the structure and function of the lipid droplet.Differential phosphorylation of perilipin 1A at the initiation of lipolysis revealed by novel monoclonal antibodies and high content analysisCD44 plays a critical role in regulating diet-induced adipose inflammation, hepatic steatosis, and insulin resistance
P2860
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P2860
FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
FSP27 contributes to efficient ...... of unilocular lipid droplets.
@ast
FSP27 contributes to efficient ...... of unilocular lipid droplets.
@en
type
label
FSP27 contributes to efficient ...... of unilocular lipid droplets.
@ast
FSP27 contributes to efficient ...... of unilocular lipid droplets.
@en
prefLabel
FSP27 contributes to efficient ...... of unilocular lipid droplets.
@ast
FSP27 contributes to efficient ...... of unilocular lipid droplets.
@en
P2093
P2860
P50
P356
P1476
FSP27 contributes to efficient ...... of unilocular lipid droplets.
@en
P2093
Asako Omachi
Hitoshi Okamura
Jinglei Cheng
Kazuhiro Kimura
Kazuo Inoue
Masato Kasuga
Masayuki Saito
Naonobu Nishino
Riko Kitazawa
Ryuji Hiramatsu
P2860
P304
P356
10.1172/JCI34090
P407
P577
2008-08-01T00:00:00Z