Genetic selection for mutations that reduce or abolish ribosomal recognition of the HIS4 translational initiator region
about
Downstream secondary structure facilitates recognition of initiator codons by eukaryotic ribosomesThe suil suppressor locus in Saccharomyces cerevisiae encodes a translation factor that functions during tRNA(iMet) recognition of the start codonFunctional elements in initiation factors 1, 1A, and 2β discriminate against poor AUG context and non-AUG start codonsThe scanning model for translation: an updateDisrupting vesicular trafficking at the endosome attenuates transcriptional activation by Gcn4.Suppression of ribosomal reinitiation at upstream open reading frames in amino acid-starved cells forms the basis for GCN4 translational controlGTP hydrolysis controls stringent selection of the AUG start codon during translation initiation in Saccharomyces cerevisiaePosttranscriptional control of gene expression in yeast.Evidence against a direct role for the Upf proteins in frameshifting or nonsense codon readthrough.RNA polymerase I-promoted HIS4 expression yields uncapped, polyadenylated mRNA that is unstable and inefficiently translated in Saccharomyces cerevisiae.Identification of compounds that decrease the fidelity of start codon recognition by the eukaryotic translational machinery.Genetic characterization of the Saccharomyces cerevisiae translational initiation suppressors sui1, sui2 and SUI3 and their effects on HIS4 expression.Genetic evidence for preferential strand transfer during meiotic recombination in yeast.The two forms of karyogamy transcription factor Kar4p are regulated by differential initiation of transcription, translation, and protein turnoverSite-directed mutagenesis of a Saccharomyces cerevisiae mitochondrial translation initiation codon.Analysis of a gene conversion gradient at the HIS4 locus in Saccharomyces cerevisiae.Non-AUG initiation of AGAMOUS mRNA translation in Arabidopsis thalianaAccumulation of a threonine biosynthetic intermediate attenuates general amino acid control by accelerating degradation of Gcn4 via Pho85 and Cdk8.Rps5-Rps16 communication is essential for efficient translation initiation in yeast S. cerevisiae.The eukaryotic initiation factor (eIF) 4G HEAT domain promotes translation re-initiation in yeast both dependent on and independent of eIF4A mRNA helicaseThe pokeweed antiviral protein specifically inhibits Ty1-directed +1 ribosomal frameshifting and retrotransposition in Saccharomyces cerevisiae.Eukaryotic translation initiation factor eIF5 promotes the accuracy of start codon recognition by regulating Pi release and conformational transitions of the preinitiation complexThe eIF1A C-terminal domain promotes initiation complex assembly, scanning and AUG selection in vivoThe C-terminal region of eukaryotic translation initiation factor 3a (eIF3a) promotes mRNA recruitment, scanning, and, together with eIF3j and the eIF3b RNA recognition motif, selection of AUG start codons.Initiation context modulates autoregulation of eukaryotic translation initiation factor 1 (eIF1)Mutations in the structural genes for eukaryotic initiation factors 2 alpha and 2 beta of Saccharomyces cerevisiae disrupt translational control of GCN4 mRNAEukaryotic translation initiation factor 5 is critical for integrity of the scanning preinitiation complex and accurate control of GCN4 translation.Identification of GCD14 and GCD15, novel genes required for translational repression of GCN4 mRNA in Saccharomyces cerevisiae.Conversion-type and restoration-type repair of DNA mismatches formed during meiotic recombination in Saccharomyces cerevisiae.The stringency of start codon selection in the filamentous fungus Neurospora crassa.An upstream ORF with non-AUG start codon is translated in vivo but dispensable for translational control of GCN4 mRNA.Retroviruses as genetic tools to isolate transcriptionally active chromosomal regions.Gle1 is a multifunctional DEAD-box protein regulator that modulates Ded1 in translation initiationTranslation of the Saccharomyces cerevisiae tcm1 gene in the absence of a 5'-untranslated leader.Control of translation initiation in Saccharomyces cerevisiae.Evidence for involvement of trans-acting factors in selection of the AUG start codon during eukaryotic translational initiation.Assembly of 60S ribosomal subunits is perturbed in temperature-sensitive yeast mutants defective in ribosomal protein L16uORFs with unusual translational start codons autoregulate expression of eukaryotic ornithine decarboxylase homologsMutational analysis of the HIS4 translational initiator region in Saccharomyces cerevisiae.Context effects and inefficient initiation at non-AUG codons in eucaryotic cell-free translation systems.
P2860
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P2860
Genetic selection for mutations that reduce or abolish ribosomal recognition of the HIS4 translational initiator region
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Genetic selection for mutation ...... translational initiator region
@ast
Genetic selection for mutation ...... translational initiator region
@en
type
label
Genetic selection for mutation ...... translational initiator region
@ast
Genetic selection for mutation ...... translational initiator region
@en
prefLabel
Genetic selection for mutation ...... translational initiator region
@ast
Genetic selection for mutation ...... translational initiator region
@en
P2860
P356
P1476
Genetic selection for mutation ...... translational initiator region
@en
P2093
T F Donahue
P2860
P304
P356
10.1128/MCB.8.7.2955
P407
P577
1988-07-01T00:00:00Z