Timing of the loss of Pten protein determines disease severity in a mouse model of myeloid malignancy.

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Stat5 is critical for the development and maintenance of myeloproliferative neoplasm initiated by Nf1 deficiency The expression pattern of Bcl11a, Mdm2 and Pten genes in B-cell acute lymphoblastic leukemia.

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P2860

Timing of the loss of Pten protein determines disease severity in a mouse model of myeloid malignancy.

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2016 nî lūn-bûn

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Timing of the loss of Pten pro ...... e model of myeloid malignancy.

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Timing of the loss of Pten pro ...... e model of myeloid malignancy.

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Timing of the loss of Pten pro ...... e model of myeloid malignancy.

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Timing of the loss of Pten pro ...... e model of myeloid malignancy.

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Timing of the loss of Pten pro ...... se model of myeloid malignancy

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Cody Webster

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Hongyu Ni

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Lijian Shao

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Natalia Colorado

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Rupak Pathak

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Shelly Y Lensing

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Wei Feng

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P2860

Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues

Chronic myelomonocytic leukemia in childhood: a retrospective analysis of 110 cases. European Working Group on Myelodysplastic Syndromes in Childhood (EWOG-MDS)

Bedside to bench in juvenile myelomonocytic leukemia: insights into leukemogenesis from a rare pediatric leukemia

Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia

Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder

Tumour predisposition in mice heterozygous for a targeted mutation in Nf1

Transcriptional activation of egr-1 by granulocyte-macrophage colony-stimulating factor but not interleukin 3 requires phosphorylation of cAMP response element-binding protein (CREB) on serine 133

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

Early growth response gene 1 stimulates development of hematopoietic progenitor cells along the macrophage lineage at the expense of the granulocyte and erythroid lineages.

Negative and positive regulation by transcription factor cAMP response element-binding protein is modulated by phosphorylation.

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1912-1922

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scholarly article

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10.1182/BLOOD-2015-05-646216

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English

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Timing of the loss of Pten protein determines disease severity in a mouse model of myeloid malignancy.

about

P2860

P2860

Timing of the loss of Pten protein determines disease severity in a mouse model of myeloid malignancy.

description

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