The CXCR4 chemokine receptor in acute and chronic leukaemia: a marrow homing receptor and potential therapeutic target.
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Stem cell competition: finding balance in the nicheThe tandem PH domain-containing protein 2 (TAPP2) regulates chemokine-induced cytoskeletal reorganization and malignant B cell migrationMucosal immunity and protection against HIV/SIV infection: strategies and challenges for vaccine design.Inhibition of gluconeogenesis in primary hepatocytes by stromal cell-derived factor-1 (SDF-1) through a c-Src/Akt-dependent signaling pathwayExtracellular calcium increases CXCR4 expression on bone marrow-derived cells and enhances pro-angiogenesis therapy.Genes of cell-cell interactions, chemotherapy detoxification and apoptosis are induced during chemotherapy of acute myeloid leukemia.Role of chemokine network in the development and progression of ovarian cancer: a potential novel pharmacological target.Immunological effects of vaccines combined with granulocyte colony-stimulating factor on a murine WEHI-3 leukemia model.Elucidating the CXCL12/CXCR4 signaling network in chronic lymphocytic leukemia through phosphoproteomics analysisTargeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia.Stem cells and bone diseases: new tools, new perspectiveCo-expression of uPAR and CXCR4 promotes tumor growth and metastasis in small cell lung cancer.GeSICA: genome segmentation from intra-chromosomal associations.A designed peptide targeting CXCR4 displays anti-acute myelocytic leukemia activity in vitro and in vivo.The N-terminal CEBPA mutant in acute myeloid leukemia impairs CXCR4 expressionDown-regulation of homeobox genes MEIS1 and HOXA in MLL-rearranged acute leukemia impairs engraftment and reduces proliferationAn interaction between hepatocyte growth factor and its receptor (c-MET) prolongs the survival of chronic lymphocytic leukemic cells through STAT3 phosphorylation: a potential role of mesenchymal cells in the diseaseDisclosing the CXCR4 expression in lymphoproliferative diseases by targeted molecular imagingImproving chemotherapeutic efficiency in acute myeloid leukemia treatments by chemically synthesized peptide interfering with CXCR4/CXCL12 axis.Effects of plerixafor in combination with BCR-ABL kinase inhibition in a murine model of CML.Ulocuplumab (BMS-936564 / MDX1338): a fully human anti-CXCR4 antibody induces cell death in chronic lymphocytic leukemia mediated through a reactive oxygen species-dependent pathwayAdhesion to osteopontin in the bone marrow niche regulates lymphoblastic leukemia cell dormancy.Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100.64Cu-AMD3100--a novel imaging agent for targeting chemokine receptor CXCR4.CXCR7 is highly expressed in acute lymphoblastic leukemia and potentiates CXCR4 response to CXCL12.The microenvironment in mature B-cell malignancies: a target for new treatment strategiesAl[18F]NOTA-T140 Peptide for Noninvasive Visualization of CXCR4 Expression.Antibodies targeting cancer stem cells: a new paradigm in immunotherapy?CXCL12/CXCR4 signaling in malignant brain tumors: a potential pharmacological therapeutic target.The microenvironment in hairy cell leukemia: pathways and potential therapeutic targets.Pediatric relapsed or refractory leukemia: new pharmacotherapeutic developments and future directions.Increased mobilization and yield of stem cells using plerixafor in combination with granulocyte-colony stimulating factor for the treatment of non-Hodgkin's lymphoma and multiple myeloma.The peculiarities of the SDF-1/CXCL12 system: in some cells, CXCR4 and CXCR7 sing solos, in others, they sing duets.Blockade of CD82 by a monoclonal antibody potentiates anti-leukemia effects of AraC in vivoUrokinase receptor and CXCR4 are regulated by common microRNAs in leukaemia cells.Intrinsic TGF-β2-triggered SDF-1-CXCR4 signaling axis is crucial for drug resistance and a slow-cycling state in bone marrow-disseminated tumor cells.Osteopontin: its potential role in cancer of children and young adults.The G protein-coupled receptor CysLT1 mediates chemokine-like effects and prolongs survival in chronic lymphocytic leukemia.Staphylococcal superantigen-like 10 inhibits CXCL12-induced human tumor cell migration.Isoform-selective phosphoinositide 3'-kinase inhibitors inhibit CXCR4 signaling and overcome stromal cell-mediated drug resistance in chronic lymphocytic leukemia: a novel therapeutic approach.
P2860
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P2860
The CXCR4 chemokine receptor in acute and chronic leukaemia: a marrow homing receptor and potential therapeutic target.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The CXCR4 chemokine receptor i ...... potential therapeutic target.
@ast
The CXCR4 chemokine receptor i ...... potential therapeutic target.
@en
type
label
The CXCR4 chemokine receptor i ...... potential therapeutic target.
@ast
The CXCR4 chemokine receptor i ...... potential therapeutic target.
@en
prefLabel
The CXCR4 chemokine receptor i ...... potential therapeutic target.
@ast
The CXCR4 chemokine receptor i ...... potential therapeutic target.
@en
P2860
P1476
The CXCR4 chemokine receptor i ...... potential therapeutic target.
@en
P2093
Andrea Bürkle
Jan A Burger
P2860
P304
P356
10.1111/J.1365-2141.2007.06590.X
P407
P577
2007-05-01T00:00:00Z