Transglutaminase 2 protects against ischemic insult, interacts with HIF1beta, and attenuates HIF1 signaling
about
Cytosolic guanine nucledotide binding deficient form of transglutaminase 2 (R580a) potentiates cell death in oxygen glucose deprivationTissue transglutaminase overexpression does not modify the disease phenotype of the R6/2 mouse model of Huntington's diseaseTransglutaminase is a therapeutic target for oxidative stress, excitotoxicity and stroke: a new epigenetic kid on the CNS blockTransglutaminase 2 has opposing roles in the regulation of cellular functions as well as cell growth and deathCellular functions of tissue transglutaminasePhysiological, pathological, and structural implications of non-enzymatic protein-protein interactions of the multifunctional human transglutaminase 2Intracellular localization and conformational state of transglutaminase 2: implications for cell death.Transglutaminase regulation of cell function.Deficiency of vasodilator-stimulated phosphoprotein (VASP) increases blood-brain-barrier damage and edema formation after ischemic stroke in miceTransglutaminase 2 exacerbates α-synuclein toxicity in mice and yeastLung cancer signature biomarkers: tissue specific semantic similarity based clustering of digital differential display (DDD) data.Transglutaminase 2: a molecular Swiss army knife.Tissue Transglutaminase Mediated Tumor-Stroma Interaction Promotes Pancreatic Cancer ProgressionDietary nitrate and nitrite modulate blood and organ nitrite and the cellular ischemic stress response.Cause and consequence: mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases.bcl-2/Adenovirus E1B 19-kd interacting protein 3 (BNIP3) regulates hypoxia-induced neural precursor cell death.New insights into the functions and localization of nuclear transglutaminase 2.The plant extracellular transglutaminase: what mammal analogues tell.Moonlighting proteins in cancer.Transglutaminase 2 modulation of NF-κB signaling in astrocytes is independent of its ability to mediate astrocytic viability in ischemic injury.Hypoxic Adaptation in the Nervous System: Promise for Novel Therapeutics for Acute and Chronic Neurodegeneration.Modulation of transglutaminase 2 activity in H9c2 cells by PKC and PKA signalling: a role for transglutaminase 2 in cytoprotection.A possible role of transglutaminase 2 in the nucleus of INS-1E and of cells of human pancreatic isletsDifferential expression of aurora-A kinase in T-cell lymphomas.Inflammation modulates expression of laminin in the central nervous system following ischemic injury.Transglutaminase 2 interaction with small heat shock proteins mediate cell survival upon excitotoxic stress.Extended ischemia prevents HIF1alpha degradation at reoxygenation by impairing prolyl-hydroxylation: role of Krebs cycle metabolitesHIF-2α in Resting Macrophages Tempers Mitochondrial Reactive Oxygen Species To Selectively Repress MARCO-Dependent Phagocytosis.Complete transglutaminase 2 ablation results in reduced stroke volumes and astrocytes that exhibit increased survival in response to ischemia.GPR56 inhibits melanoma growth by internalizing and degrading its ligand TG2.Transglutaminase 2 ablation leads to mitophagy impairment associated with a metabolic shift towards aerobic glycolysis.Transglutaminase 2 facilitates or ameliorates HIF signaling and ischemic cell death depending on its conformation and localization.Transglutaminase 2 protects against ischemic stroke.Depletion of transglutaminase 2 in neurons alters expression of extracellular matrix and signal transduction genes and compromises cell viability.Subcellular localization patterns of transglutaminase 2 in astrocytes and neurons are differentially altered by hypoxia.Mutations in TGM6 induce the unfolded protein response in SCA35.CHIP-mediated degradation of transglutaminase 2 negatively regulates tumor growth and angiogenesis in renal cancer.Prognostic role of tissue transglutaminase 2 in colon carcinoma.Transglutaminase 2: Friend or foe? The discordant role in neurons and astrocytes.Role and predictive strength of transglutaminase type 2 expression in premalignant lesions of the cervix.
P2860
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P2860
Transglutaminase 2 protects against ischemic insult, interacts with HIF1beta, and attenuates HIF1 signaling
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Transglutaminase 2 protects ag ...... and attenuates HIF1 signaling
@ast
Transglutaminase 2 protects ag ...... and attenuates HIF1 signaling
@en
type
label
Transglutaminase 2 protects ag ...... and attenuates HIF1 signaling
@ast
Transglutaminase 2 protects ag ...... and attenuates HIF1 signaling
@en
prefLabel
Transglutaminase 2 protects ag ...... and attenuates HIF1 signaling
@ast
Transglutaminase 2 protects ag ...... and attenuates HIF1 signaling
@en
P2093
P2860
P356
P1433
P1476
Transglutaminase 2 protects ag ...... and attenuates HIF1 signaling
@en
P2093
Anthony J Filiano
Gail V W Johnson
Janusz Tucholski
Soner Gundemir
P2860
P304
P356
10.1096/FJ.07-097709
P407
P577
2008-03-28T00:00:00Z