Development of a physiologically based pharmacokinetic model of actinomycin D in children with cancer.

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A mathematical theory of the transcription repression (TR) therapy of cancer - whether and how it may work.Why has model-informed precision dosing not yet become common clinical reality? lessons from the past and a roadmap for the future.

P2860

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P2860

Development of a physiologically based pharmacokinetic model of actinomycin D in children with cancer.

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2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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2016年论文

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2016年论文

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Development of a physiological ...... cin D in children with cancer.

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Development of a physiological ...... cin D in children with cancer.

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Development of a physiological ...... cin D in children with cancer.

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Development of a physiological ...... cin D in children with cancer.

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Development of a physiological ...... cin D in children with cancer.

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Development of a physiological ...... ycin D in children with cancer

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Christopher Walsh

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Jennifer J Bonner

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John G Gribben

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Trevor N Johnson

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P2860

Characterisation of the clinical pharmacokinetics of actinomycin D and the influence of ABCB1 pharmacogenetic variation on actinomycin D disposition in children with cancer.

Hepatic cytochrome P450 3A drug metabolism is reduced in cancer patients who have an acute-phase response.

Optimal duration of preoperative therapy in unilateral and nonmetastatic Wilms' tumor in children older than 6 months: results of the Ninth International Society of Pediatric Oncology Wilms' Tumor Trial and Study.

A semi-mechanistic model to predict the effects of liver cirrhosis on drug clearance.

Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children.

Guide to Receptors and Channels (GRAC), 5th edition.

Dactinomycin and vincristine toxicity in the treatment of childhood cancer: a retrospective study from the Children's Oncology Group

Basis of actinomycin action. I. DNA binding and inhibition of RNA-polymerase synthetic reactions by actinomycin

Characterisation of the roles of ABCB1, ABCC1, ABCC2 and ABCG2 in the transport and pharmacokinetics of actinomycin D in vitro and in vivo.

GAMEC--a new intensive protocol for untreated poor prognosis and relapsed or refractory germ cell tumours.

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989-998

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scholarly article

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10.1111/BCP.12878

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English

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2016-02-25T00:00:00Z

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Development of a physiologically based pharmacokinetic model of actinomycin D in children with cancer.

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P2860

P2860

Development of a physiologically based pharmacokinetic model of actinomycin D in children with cancer.

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P1476

P2093

P2860

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P932