The phosphorylation state of serine 256 is dominant over that of serine 261 in the regulation of AQP2 trafficking in renal epithelial cells.
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Role of multiple phosphorylation sites in the COOH-terminal tail of aquaporin-2 for water transport: evidence against channel gatingSerine 269 phosphorylated aquaporin-2 is targeted to the apical membrane of collecting duct principal cellsIdentification of phosphorylation-dependent binding partners of aquaporin-2 using protein mass spectrometryA plate reader-based method for cell water permeability measurement.Phosphorylation of aquaporin-2 regulates its endocytosis and protein-protein interactions.Vasopressin-2 receptor signaling and autosomal dominant polycystic kidney disease: from bench to bedside and back again.Sensing, signaling and sorting events in kidney epithelial cell physiology.Electrolytes in the aging.Differential, phosphorylation dependent trafficking of AQP2 in LLC-PK1 cellsPhosphorylation of aquaporin-2 regulates its water permeabilityPotentiation of the effect of thiazide derivatives by carbonic anhydrase inhibitors: molecular mechanisms and potential clinical implicationsBilateral ureteral obstruction induces early downregulation and redistribution of AQP2 and phosphorylated AQP2.Simvastatin enhances aquaporin-2 surface expression and urinary concentration in vasopressin-deficient Brattleboro rats through modulation of Rho GTPase.Polarized Trafficking of AQP2 Revealed in Three Dimensional Epithelial Culture.NSAIDs Alter Phosphorylated Forms of AQP2 in the Inner Medullary Tip.Characterization of the putative phosphorylation sites of the AQP2 C terminus and their role in AQP2 trafficking in LLC-PK1 cells.Aquaporin 2 promotes cell migration and epithelial morphogenesis.Acute hypertonicity alters aquaporin-2 trafficking and induces a MAPK-dependent accumulation at the plasma membrane of renal epithelial cells.Remote ischemic perconditioning attenuates ischemia/reperfusion-induced downregulation of AQP2 in rat kidney.Phosphorylation events and the modulation of aquaporin 2 cell surface expressionVasopressin and the regulation of aquaporin-2Localization and trafficking of aquaporin 2 in the kidney.Aquaporin-2 in the "-omics" eraSyntaxin specificity of aquaporins in the inner medullary collecting ductAQP2 Plasma Membrane Diffusion Is Altered by the Degree of AQP2-S256 Phosphorylation.Regulation of the water channel aquaporin-2 by posttranslational modification.Mechanisms of cell polarity and aquaporin sorting in the nephron.Molecular biology of water and salt regulation in the kidney.Cell culture models and animal models for studying the patho-physiological role of renal aquaporins.Congenital nephrogenic diabetes insipidus: the current state of affairs.Dynamic regulation and dysregulation of the water channel aquaporin-2: a common cause of and promising therapeutic target for water balance disorders.ILK and cytoskeletal architecture: an important determinant of AQP2 recycling and subsequent entry into the exocytotic pathway.Protein phosphatase 2C is responsible for VP-induced dephosphorylation of AQP2 serine 261.Regulation of AQP2 localization by S256 and S261 phosphorylation and ubiquitination.Reciprocal regulation of aquaporin-2 abundance and degradation by protein kinase A and p38-MAP kinase.EGF Receptor Inhibition by Erlotinib Increases Aquaporin 2-Mediated Renal Water Reabsorption.Phosphatase inhibition increases AQP2 accumulation in the rat IMCD apical plasma membrane.Vasopressin increases S261 phosphorylation in AQP2-P262L, a mutant in recessive nephrogenic diabetes insipidus.Manganese promotes intracellular accumulation of AQP2 via modulating F-actin polymerization and reduces urinary concentration in mice.Hereditary Nephrogenic Diabetes Insipidus: Pathophysiology and Possible Treatment. An Update.
P2860
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P2860
The phosphorylation state of serine 256 is dominant over that of serine 261 in the regulation of AQP2 trafficking in renal epithelial cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The phosphorylation state of s ...... ing in renal epithelial cells.
@ast
The phosphorylation state of s ...... ing in renal epithelial cells.
@en
type
label
The phosphorylation state of s ...... ing in renal epithelial cells.
@ast
The phosphorylation state of s ...... ing in renal epithelial cells.
@en
prefLabel
The phosphorylation state of s ...... ing in renal epithelial cells.
@ast
The phosphorylation state of s ...... ing in renal epithelial cells.
@en
P2093
P2860
P1476
The phosphorylation state of s ...... ing in renal epithelial cells.
@en
P2093
Dennis Brown
Hua Jenny Lu
Quan-Hong Qin
Richard Bouley
Toshiyuki Matsuzaki
Udo Hasler
P2860
P304
P356
10.1152/AJPRENAL.00072.2008
P577
2008-04-23T00:00:00Z