Interleukin-1beta-dependent signaling between astrocytes and neurons depends critically on astrocytic calcineurin/NFAT activity. - Wikidata - awgldk - TriplyDB

Interleukin-1beta-dependent signaling between astrocytes and neurons depends critically on astrocytic calcineurin/NFAT activity.

Interleukin-1beta-dependent signaling between astrocytes and neurons depends critically on astrocytic calcineurin/NFAT activity.

http://www.wikidata.org/entity/Q36808464

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The Emerging Roles of the Calcineurin-Nuclear Factor of Activated T-Lymphocytes Pathway in Nervous System Functions and Diseases Inhibition of soluble tumor necrosis factor ameliorates synaptic alterations and Ca2+ dysregulation in aged rats Disparate effects of serum on basal and evoked NFAT activity in primary astrocyte cultures Simulated whiplash modulates expression of the glutamatergic system in the spinal cord suggesting spinal plasticity is associated with painful dynamic cervical facet loading.Astrocyte-derived growth factors and estrogen neuroprotection: role of transforming growth factor-α in estrogen-induced upregulation of glutamate transporters in astrocytes Nuclear factor of activated T-cells isoform c4 (NFATc4/NFAT3) as a mediator of antiapoptotic transcription in NMDA receptor-stimulated cortical neurons TNF-α contributes to caspase-3 independent apoptosis in neuroblastoma cells: role of NFAT Ginsenoside Rg1 prevents cognitive impairment and hippocampus senescence in a rat model of D-galactose-induced aging.Microglial phenotype is regulated by activity of the transcription factor, NFAT (nuclear factor of activated T cells).Calcineurin and glial signaling: neuroinflammation and beyond Proteolysis of calcineurin is increased in human hippocampus during mild cognitive impairment and is stimulated by oligomeric Abeta in primary cell culture.Calcyclin-binding protein/Siah-1-interacting protein as a regulator of transcriptional responses in brain cells.PMA and ionomycin induce glioblastoma cell death: activation-induced cell-death-like phenomena occur in glioma cells Progesterone inhibition of voltage-gated calcium channels is a potential neuroprotective mechanism against excitotoxicity Attenuation of microglial activation in a mouse model of Alzheimer's disease via NFAT inhibition IL-1 interacts with ethanol effects on GABAergic transmission in the mouse central amygdala Toll-Like Receptors Promote Mitochondrial Translocation of Nuclear Transcription Factor Nuclear Factor of Activated T-Cells in Prolonged Microglial Activation.Synapse loss induced by interleukin-1β requires pre- and post-synaptic mechanisms The participation of insulin-like growth factor-binding protein 3 released by astrocytes in the pathology of Alzheimer's disease.Blockade of Astrocytic Calcineurin/NFAT Signaling Helps to Normalize Hippocampal Synaptic Function and Plasticity in a Rat Model of Traumatic Brain Injury.The TNFα-Transgenic Rat: Hippocampal Synaptic Integrity, Cognition, Function, and Post-Ischemic Cell Loss.Ulinastatin attenuates neuropathic pain induced by L5-VRT via the calcineurin/IL-10 pathway.Inducible nitric oxide synthase (NOS-2) in subarachnoid hemorrhage: Regulatory mechanisms and therapeutic implications.Amyloid-β1-42 slows clearance of synaptically released glutamate by mislocalizing astrocytic GLT-1.Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling.Expression of miR-15/107 family microRNAs in human tissues and cultured rat brain cells.Interleukin-1 and stroke: biomarker, harbinger of damage, and therapeutic target.Neuroimmunomodulation by calcineurin in aging and Alzheimer's disease.Calcium dysregulation and neuroinflammation: discrete and integrated mechanisms for age-related synaptic dysfunction.Preparation of acute hippocampal slices from rats and transgenic mice for the study of synaptic alterations during aging and amyloid pathology.Pomegranate polyphenols and extract inhibit nuclear factor of activated T-cell activity and microglial activation in vitro and in a transgenic mouse model of Alzheimer disease Cooperative roles of NF-κB and NFAT4 in polyomavirus JC regulation at the KB control element.NFATs and Alzheimer's Disease.Calcineurin/NFAT Signaling in Activated Astrocytes Drives Network Hyperexcitability in Aβ-Bearing Mice.Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.Calcineurin proteolysis in astrocytes: Implications for impaired synaptic function Epithelial calcineurin controls microbiota-dependent intestinal tumor development.Stimulation of IL-1β and IL-6 through NF-κB and sonic hedgehog-dependent pathways in mouse astrocytes by excretory/secretory products of fifth-stage larval Angiostrongylus cantonensis.Angiotensin-(1-7) prevents radiation-induced inflammation in rat primary astrocytes through regulation of MAP kinase signaling.Early stage drug treatment that normalizes proinflammatory cytokine production attenuates synaptic dysfunction in a mouse model that exhibits age-dependent progression of Alzheimer's disease-related pathology.

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P2860

Interleukin-1beta-dependent signaling between astrocytes and neurons depends critically on astrocytic calcineurin/NFAT activity.

http://www.wikidata.org/entity/Q36808464

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2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

Interleukin-1beta-dependent si ...... tic calcineurin/NFAT activity.

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Interleukin-1beta-dependent si ...... tic calcineurin/NFAT activity.

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Interleukin-1beta-dependent si ...... tic calcineurin/NFAT activity.

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Interleukin-1beta-dependent si ...... tic calcineurin/NFAT activity.

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Interleukin-1beta-dependent si ...... tic calcineurin/NFAT activity.

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Interleukin-1beta-dependent si ...... ytic calcineurin/NFAT activity

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P2093

Christopher M Norris

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Diana M Mathis

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Hafiz Mohmmad Abdul

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Irina A Artiushin

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Jennifer L Furman

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Michelle A Sama

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P2860

Direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth

Recombinant NFAT1 (NFATp) is regulated by calcineurin in T cells and mediates transcription of several cytokine genes

The interleukin-1 signalling pathway in astrocytes: a key contributor to inflammation in the brain

Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD

Selective inhibition of NFAT activation by a peptide spanning the calcineurin targeting site of NFAT

Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy

Mutations in amyloid precursor protein and presenilin-1 genes increase the basal oxidative stress in murine neuronal cells and lead to increased sensitivity to oxidative stress mediated by amyloid beta-peptide (1-42), HO and kainic acid: implication

Transcriptional regulation by calcium, calcineurin, and NFAT

Interleukin-1beta activates forebrain glial cells and increases nitric oxide production and cortical glutamate and GABA release in vivo: implications for Alzheimer's disease.

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21953-21964

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10.1074/JBC.M800148200

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32

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283

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18541537

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