Rac-specific guanine nucleotide exchange factor DOCK1 is a critical regulator of HER2-mediated breast cancer metastasis.
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ROBO1, a tumor suppressor and critical molecular barrier for localized tumor cells to acquire invasive phenotype: study in African-American and Caucasian prostate cancer modelsThe Rac-specific exchange factors Dock1 and Dock5 are dispensable for the establishment of the glomerular filtration barrier in vivo.Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis.Axl phosphorylates Elmo scaffold proteins to promote Rac activation and cell invasion.Mycophenolic acid inhibits migration and invasion of gastric cancer cells via multiple molecular pathways.TGF-β/Smad signaling through DOCK4 facilitates lung adenocarcinoma metastasisImpaired cell death and mammary gland involution in the absence of Dock1 and Rac1 signaling.Protein kinase A-dependent phosphorylation of Dock180 at serine residue 1250 is important for glioma growth and invasion stimulated by platelet derived-growth factor receptor α.Loss of the E3 ubiquitin ligase HACE1 results in enhanced Rac1 signaling contributing to breast cancer progression.DOCK2 and DOCK5 act additively in neutrophils to regulate chemotaxis, superoxide production, and extracellular trap formationMinireview: Mouse Models of Rho GTPase Function in Mammary Gland Development, Tumorigenesis, and MetastasisThe putative tumor activator ARHGEF3 promotes nasopharyngeal carcinoma cell pathogenesis by inhibiting cellular apoptosisThe accessory proteins REEP5 and REEP6 refine CXCR1-mediated cellular responses and lung cancer progression.The glucose transporter GLUT1 is required for ErbB2-induced mammary tumorigenesis.Knockdown of ELMO3 Suppresses Growth, Invasion and Metastasis of Colorectal Cancer.The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitriesThe focal adhesion-associated proteins DOCK5 and GIT2 comprise a rheostat in control of epithelial invasion.Insights into the biological functions of Dock family guanine nucleotide exchange factors.When Good Turns Bad: Regulation of Invasion and Metastasis by ErbB2 Receptor Tyrosine Kinase.The Cdc42/Rac1 regulator CdGAP is a novel E-cadherin transcriptional co-repressor with Zeb2 in breast cancer.Downregulation of DOCK1 sensitizes bladder cancer cells to cisplatin through preventing epithelial-mesenchymal transition.Directional Migration in Esophageal Squamous Cell Carcinoma (ESCC) is Epigenetically Regulated by SET Nuclear Oncogene, a Member of the Inhibitor of Histone Acetyltransferase Complex.High expression of dedicator of cytokinesis 1 (DOCK1) confers poor prognosis in acute myeloid leukemia.The R-enantiomer of ketorolac delays mammary tumor development in mouse mammary tumor virus-polyoma middle T antigen (MMTV-PyMT) mice.CdGAP/ARHGAP31 is regulated by RSK phosphorylation and binding to 14-3-3β adaptor protein.DNA Methylation Levels of the ELMO Gene Promoter CpG Islands in Human Glioblastomas.Contributions of the RhoA guanine nucleotide exchange factor Net1 to polyoma middle T antigen-mediated mammary gland tumorigenesis and metastasis.
P2860
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P2860
Rac-specific guanine nucleotide exchange factor DOCK1 is a critical regulator of HER2-mediated breast cancer metastasis.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Rac-specific guanine nucleotid ...... ated breast cancer metastasis.
@en
type
label
Rac-specific guanine nucleotid ...... ated breast cancer metastasis.
@en
prefLabel
Rac-specific guanine nucleotid ...... ated breast cancer metastasis.
@en
P2093
P2860
P356
P1476
Rac-specific guanine nucleotid ...... ated breast cancer metastasis.
@en
P2093
Ariane Pelletier
Jean-François Côté
Jennifer Huber
Morag Park
Mélanie Laurin
Tarek Houalla
William J Muller
P2860
P304
P356
10.1073/PNAS.1213050110
P407
P577
2013-04-16T00:00:00Z