Centrosome biogenesis and function: centrosomics brings new understanding.
about
Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancerCentrosomal localization of the psoriasis candidate gene product, CCHCR1, supports a role in cytoskeletal organizationNovel asymmetrically localizing components of human centrosomes identified by complementary proteomics methodsEnd-binding protein 1 controls signal propagation from the T cell receptor.Poc1A and Poc1B act together in human cells to ensure centriole integrityThe oral-facial-digital syndrome gene C2CD3 encodes a positive regulator of centriole elongation.Polo-like kinase 2-dependent phosphorylation of NPM/B23 on serine 4 triggers centriole duplicationCep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosomeComponents of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunctionCDK6 associates with the centrosome during mitosis and is mutated in a large Pakistani family with primary microcephalyPLK2 phosphorylation is critical for CPAP function in procentriole formation during the centrosome cycleSperiolin is a novel human and mouse sperm centrosome proteinThe CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assemblySCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity through CP110 degradationStress-induced localization of HSPA6 (HSP70B') and HSPA1A (HSP70-1) proteins to centrioles in human neuronal cellsCep72 regulates the localization of key centrosomal proteins and proper bipolar spindle formationPitchfork regulates primary cilia disassembly and left-right asymmetryCP110 suppresses primary cilia formation through its interaction with CEP290, a protein deficient in human ciliary diseaseWhole-exome sequencing identifies KIZ as a ciliary gene associated with autosomal-recessive rod-cone dystrophyThe transition from meiotic to mitotic spindle assembly is gradual during early mammalian developmentThe evolution of land plant ciliaMolecular complexes that direct rhodopsin transport to primary ciliaA cell cycle role for the epigenetic factor CTCF-L/BORISMLL5 maintains spindle bipolarity by preventing aberrant cytosolic aggregation of PLK1Targeting of Fzr/Cdh1 for timely activation of the APC/C at the centrosome during mitotic exit.Structure of the SAS-6 cartwheel hub from Leishmania majorThe PLK4-STIL-SAS-6 module at the core of centriole duplicationCentrosome - a promising anti-cancer targetNew frontiers: discovering cilia-independent functions of cilia proteinsCharacterization of Cep85 - a new antagonist of Nek2A that is involved in the regulation of centrosome disjunctionCDK5RAP2 regulates centriole engagement and cohesion in miceSDCCAG8 regulates pericentriolar material recruitment and neuronal migration in the developing cortexAcentriolar mitosis activates a p53-dependent apoptosis pathway in the mouse embryoTumor-Derived Factors and Reduced p53 Promote Endothelial Cell Centrosome Over-DuplicationAhi1, whose human ortholog is mutated in Joubert syndrome, is required for Rab8a localization, ciliogenesis and vesicle traffickingHook3 interacts with PCM1 to regulate pericentriolar material assembly and the timing of neurogenesisEvolution: Tracing the origins of centrioles, cilia, and flagellaSubdiffraction-resolution fluorescence microscopy reveals a domain of the centrosome critical for pericentriolar material organization.SAS-4 is recruited to a dynamic structure in newly forming centrioles that is stabilized by the gamma-tubulin-mediated addition of centriolar microtubules.Xenopus TACC3/maskin is not required for microtubule stability but is required for anchoring microtubules at the centrosome.
P2860
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P2860
Centrosome biogenesis and function: centrosomics brings new understanding.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Centrosome biogenesis and function: centrosomics brings new understanding.
@en
type
label
Centrosome biogenesis and function: centrosomics brings new understanding.
@en
prefLabel
Centrosome biogenesis and function: centrosomics brings new understanding.
@en
P356
P1476
Centrosome biogenesis and function: centrosomics brings new understanding.
@en
P2888
P304
P356
10.1038/NRM2180
P577
2007-06-01T00:00:00Z