Reduced Oct4 expression directs a robust pluripotent state with distinct signaling activity and increased enhancer occupancy by Oct4 and Nanog
about
Integration of Signaling Pathways with the Epigenetic Machinery in the Maintenance of Stem CellsPluripotency Factors on Their Lineage MovePotential Gene Interactions in the Cell Cycles of Gametes, Zygotes, Embryonic Stem Cells and the Development of CancerWnt/ß-catenin signalling and the dynamics of fate decisions in early mouse embryos and embryonic stem (ES) cellsFrom blastocyst to gastrula: gene regulatory networks of embryonic stem cells and early mouse embryogenesisRole of Oct4 in the early embryo developmentChromatin features and the epigenetic regulation of pluripotency states in ESCsEx uno plures: molecular designs for embryonic pluripotencyThe role of pluripotency gene regulatory network components in mediating transitions between pluripotent cell statesGene networks of fully connected triads with complete auto-activation enable multistability and stepwise stochastic transitionsMolecular basis of embryonic stem cell self-renewal: from signaling pathways to pluripotency networkA novel nodal enhancer dependent on pluripotency factors and smad2/3 signaling conditions a regulatory switch during epiblast maturationToward pluripotency by reprogramming: mechanisms and applicationDistinct Signaling Requirements for the Establishment of ESC Pluripotency in Late-Stage EpiSCsMicrofluidic isolation of highly pure embryonic stem cells using feeder-separated co-culture system.MCA: Multiresolution Correlation Analysis, a graphical tool for subpopulation identification in single-cell gene expression data.Gene expression variability in mammalian embryonic stem cells using single cell RNA-seq dataMolecular control of induced pluripotency.INO80 facilitates pluripotency gene activation in embryonic stem cell self-renewal, reprogramming, and blastocyst development.Gene expression variability as a unifying element of the pluripotency network.Dax1 and Nanog act in parallel to stabilize mouse embryonic stem cells and induced pluripotencyActivin/Nodal signalling before implantation: setting the stage for embryo patterning.Towards elucidating the connection between epithelial-mesenchymal transitions and stemnessStability of the hybrid epithelial/mesenchymal phenotype.RNA-binding proteins in pluripotency, differentiation, and reprogramming.A model-based analysis of culture-dependent phenotypes of mESCs.Mammalian transcriptional hotspots are enriched for tissue specific enhancers near cell type specific highly expressed genes and are predicted to act as transcriptional activator hubs.Large-scale time-lapse microscopy of Oct4 expression in human embryonic stem cell colonies.Wnt/Tcf1 pathway restricts embryonic stem cell cycle through activation of the Ink4/Arf locusA Dynamic Role of TBX3 in the Pluripotency Circuitry.Coupling the modules of EMT and stemness: A tunable 'stemness window' modelThe emerging roles of Oct4 in tumor-initiating cells.Nanog, Oct4 and Tet1 interplay in establishing pluripotencyOct transcription factors in development and stem cells: insights and mechanisms.Age-related yield of adipose-derived stem cells bearing the low-affinity nerve growth factor receptor.ISSCR 2013: back to Bean Town.Multiple Roles of MYC in Integrating Regulatory Networks of Pluripotent Stem Cells.Do all roads lead to Oct4? the emerging concepts of induced pluripotency.Multi-layered global gene regulation in mouse embryonic stem cells.Mapping the route from naive pluripotency to lineage specification.
P2860
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P2860
Reduced Oct4 expression directs a robust pluripotent state with distinct signaling activity and increased enhancer occupancy by Oct4 and Nanog
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Reduced Oct4 expression direct ...... er occupancy by Oct4 and Nanog
@en
type
label
Reduced Oct4 expression direct ...... er occupancy by Oct4 and Nanog
@en
prefLabel
Reduced Oct4 expression direct ...... er occupancy by Oct4 and Nanog
@en
P2093
P2860
P50
P1433
P1476
Reduced Oct4 expression direct ...... er occupancy by Oct4 and Nanog
@en
P2093
Alessia Gagliardi
Andrea Y Weiße
Douglas Colby
Frederick C K Wong
Huck-Hui Ng
Jia Hui Ng
Nicola Festuccia
Rodrigo Osorno
Simon R Tomlinson
Violetta Karwacki-Neisius
P2860
P304
P356
10.1016/J.STEM.2013.04.023
P407
P577
2013-05-01T00:00:00Z