GAL4 of Saccharomyces cerevisiae activates the lactose-galactose regulon of Kluyveromyces lactis and creates a new phenotype: glucose repression of the regulon
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Yeast carbon catabolite repressionThe Schizosaccharomyces pombe homolog of Saccharomyces cerevisiae HAP2 reveals selective and stringent conservation of the small essential core protein domain.Transcriptional control of the GAL/MEL regulon of yeast Saccharomyces cerevisiae: mechanism of galactose-mediated signal transduction.Sequence conservation in the Saccharomyces and Kluveromyces GAL11 transcription activators suggests functional domainsGenetic evidence for similar negative regulatory domains in the yeast transcription activators GAL4 and LAC9The organization and transcription of the galactose gene cluster of Kluyveromyces lactisRegulation of sugar utilization in Saccharomyces speciesAdaptive evolution of a lactose-consuming Saccharomyces cerevisiae recombinant.Constitutive expression in gal7 mutants of Kluyveromyces lactis is due to internal production of galactose as an inducer of the Gal/Lac regulon.Identification of base and backbone contacts used for DNA sequence recognition and high-affinity binding by LAC9, a transcription activator containing a C6 zinc finger.GAL4 protein: purification, association with GAL80 protein, and conserved domain structure.The C6 zinc finger and adjacent amino acids determine DNA-binding specificity and affinity in the yeast activator proteins LAC9 and PPR1.Galactokinase encoded by GAL1 is a bifunctional protein required for induction of the GAL genes in Kluyveromyces lactis and is able to suppress the gal3 phenotype in Saccharomyces cerevisiaeInteraction between transcriptional activator protein LAC9 and negative regulatory protein GAL80The signal for glucose repression of the lactose-galactose regulon is amplified through subtle modulation of transcription of the Kluyveromyces lactis Kl-GAL4 activator gene.Characterization of a positive regulatory gene, LAC9, that controls induction of the lactose-galactose regulon of Kluyveromyces lactis: structural and functional relationships to GAL4 of Saccharomyces cerevisiaeCysteine residues in the zinc finger and amino acids adjacent to the finger are necessary for DNA binding by the LAC9 regulatory protein of Kluyveromyces lactisA model fungal gene regulatory mechanism: the GAL genes of Saccharomyces cerevisiae.Glucose repression of lactose/galactose metabolism in Kluyveromyces lactis is determined by the concentration of the transcriptional activator LAC9 (K1GAL4) [corrected]A mutation in the Zn-finger of the GAL4 homolog LAC9 results in glucose repression of its target genes.The Gal3p-Gal80p-Gal4p transcription switch of yeast: Gal3p destabilizes the Gal80p-Gal4p complex in response to galactose and ATP.Coregulation of the Kluyveromyces lactis lactose permease and beta-galactosidase genes is achieved by interaction of multiple LAC9 binding sites in a 2.6 kbp divergent promoter.Gal80 proteins of Kluyveromyces lactis and Saccharomyces cerevisiae are highly conserved but contribute differently to glucose repression of the galactose regulon.Functional homology between the yeast regulatory proteins GAL4 and LAC9: LAC9-mediated transcriptional activation in Kluyveromyces lactis involves protein binding to a regulatory sequence homologous to the GAL4 protein-binding site.Review: compilation and characteristics of dedicated transcription factors in Saccharomyces cerevisiae.Signaling activation and repression of RNA polymerase II transcription in yeast.Fructose-1,6-bisphosphatase of the yeast Kluyveromyces lactis.Experimental and steady-state analysis of the GAL regulatory system in Kluyveromyces lactis.The galactose switch in Kluyveromyces lactis depends on nuclear competition between Gal4 and Gal1 for Gal80 binding.The alcohol dehydrogenase system in the yeast, Kluyveromyces lactis.
P2860
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P2860
GAL4 of Saccharomyces cerevisiae activates the lactose-galactose regulon of Kluyveromyces lactis and creates a new phenotype: glucose repression of the regulon
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
1987年论文
@zh
1987年论文
@zh-cn
name
GAL4 of Saccharomyces cerevisi ...... cose repression of the regulon
@en
type
label
GAL4 of Saccharomyces cerevisi ...... cose repression of the regulon
@en
prefLabel
GAL4 of Saccharomyces cerevisi ...... cose repression of the regulon
@en
P2093
P2860
P356
P1476
GAL4 of Saccharomyces cerevisi ...... cose repression of the regulon
@en
P2093
J E Hopper
R C Dickson
S A Johnston
P2860
P304
P356
10.1128/MCB.7.2.780
P407
P577
1987-02-01T00:00:00Z