Protection against malaria after immunization by chloroquine prophylaxis and sporozoites is mediated by preerythrocytic immunity.
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Malaria vaccines: identifying Plasmodium falciparum liver-stage targetsCD8(+) T cells mediate robust stage-specific immunity to P. berghei under chemoprophylaxis and this protective environment is not downregulated by the presence of blood-stage infectionThe March Toward Malaria VaccinesExternal quality assurance of malaria nucleic acid testing for clinical trials and eradication surveillanceSporozoite immunization of human volunteers under mefloquine prophylaxis is safe, immunogenic and protective: a double-blind randomized controlled clinical trialImmunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trialHigh Sporozoite Antibody Titers in Conjunction with Microscopically Detectable Blood Infection Display Signatures of Protection from Clinical MalariaEngineering of Genetically Arrested Parasites (GAPs) For a Precision Malaria VaccineHuman vaccination against Plasmodium vivax Duffy-binding protein induces strain-transcending antibodies.Malaria immunity in man and mosquito: insights into unsolved mysteries of a deadly infectious disease.Identification of pre-erythrocytic malaria antigens that target hepatocytes for killing in vivo and contribute to protection elicited by whole-parasite vaccination.Artesunate versus chloroquine infection-treatment-vaccination defines stage-specific immune responses associated with prolonged sterile protection against both pre-erythrocytic and erythrocytic Plasmodium yoelii infection.Expansion of IgG+ B-cells during mitogen stimulation for memory B-cell ELISpot analysis is influenced by size and composition of the B-cell pool.Sporozoite immunization of human volunteers under chemoprophylaxis induces functional antibodies against pre-erythrocytic stages of Plasmodium falciparum.Translating the immunogenicity of prime-boost immunization with ChAd63 and MVA ME-TRAP from malaria naive to malaria-endemic populationsCytotoxic markers associate with protection against malaria in human volunteers immunized with Plasmodium falciparum sporozoites.A combined analysis of immunogenicity, antibody kinetics and vaccine efficacy from phase 2 trials of the RTS,S malaria vaccine.Memory B-cell and antibody responses induced by Plasmodium falciparum sporozoite immunization.The case for a rational genome-based vaccine against malaria.Blood-stage immunity to Plasmodium chabaudi malaria following chemoprophylaxis and sporozoite immunizationDirect venous inoculation of Plasmodium falciparum sporozoites for controlled human malaria infection: a dose-finding trial in two centres.Chloroquine neither eliminates liver stage parasites nor delays their development in a murine Chemoprophylaxis Vaccination model.Impact of malaria preexposure on antiparasite cellular and humoral immune responses after controlled human malaria infection.Heterologous Protection against Malaria after Immunization with Plasmodium falciparum Sporozoites.Controlled human malaria infection by intramuscular and direct venous inoculation of cryopreserved Plasmodium falciparum sporozoites in malaria-naïve volunteers: effect of injection volume and dose on infectivity ratesBreadth of humoral response and antigenic targets of sporozoite-inhibitory antibodies associated with sterile protection induced by controlled human malaria infectionThe Power of Malaria Vaccine Trials Using Controlled Human Malaria Infection.Safety, Immunogenicity, and Protective Efficacy of Intradermal Immunization with Aseptic, Purified, Cryopreserved Plasmodium falciparum Sporozoites in Volunteers Under Chloroquine Prophylaxis: A Randomized Controlled Trial.Immunogenicity of a chimeric Plasmodium falciparum merozoite surface protein vaccine in Aotus monkeys.ESAT-6-dependent cytosolic pattern recognition drives noncognate tuberculosis control in vivoPre-erythrocytic antibody profiles induced by controlled human malaria infections in healthy volunteers under chloroquine prophylaxis.Diagnosis and treatment based on quantitative PCR after controlled human malaria infection.Measurement of the T Cell Response to Preerythrocytic Vaccination in Mice.Challenges of assessing the clinical efficacy of asexual blood-stage Plasmodium falciparum malaria vaccinesCD8 T cell independent immunity after single dose infection-treatment-vaccination (ITV) against Plasmodium yoelii.Decreased growth rate of P. falciparum blood stage parasitemia with age in a holoendemic population.Analysis of human B-cell responses following ChAd63-MVA MSP1 and AMA1 immunization and controlled malaria infection.The path of malaria vaccine development: challenges and perspectives.Correlates of protective immunity following whole sporozoite vaccination against malaria.Live attenuated pre-erythrocytic malaria vaccines.
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P2860
Protection against malaria after immunization by chloroquine prophylaxis and sporozoites is mediated by preerythrocytic immunity.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Protection against malaria aft ...... d by preerythrocytic immunity.
@en
type
label
Protection against malaria aft ...... d by preerythrocytic immunity.
@en
prefLabel
Protection against malaria aft ...... d by preerythrocytic immunity.
@en
P2093
P2860
P50
P921
P356
P1476
Protection against malaria aft ...... d by preerythrocytic immunity.
@en
P2093
André J A M van der Ven
Anne C Teirlinck
Annemieke Jansens
Ben C L van Schaijk
Cornelus C Hermsen
Dunja Zimmerman
Else M Bijker
Guido J H Bastiaens
Jaco J Verweij
Jorien Wiersma
P2860
P304
P356
10.1073/PNAS.1220360110
P407
P50
P577
2013-04-18T00:00:00Z