Drug metabolite profiling and elucidation of drug-induced hepatotoxicity.
about
The ToxBank Data Warehouse: Supporting the Replacement of In Vivo Repeated Dose Systemic Toxicity TestingModeling liver-related adverse effects of drugs using knearest neighbor quantitative structure-activity relationship method.Prediction of adverse drug reactions using decision tree modeling.Network-based assessment of the selectivity of metabolic drug targets in Plasmodium falciparum with respect to human liver metabolismUse of proteomics for the discovery of early markers of drug toxicity.Cytochrome P450-mediated bioactivation of the epidermal growth factor receptor inhibitor erlotinib to a reactive electrophileFulminate Hepatic Failure in a 5 Year Old Female after Inappropriate Acetaminophen Treatment.Advancement of structure-activity relationship of multidrug resistance-associated protein 2 interactions.Metabolic bioactivation and drug-related adverse effects: current status and future directions from a pharmaceutical research perspective.Animal models of idiosyncratic drug-induced liver injury--current status.The primary role of hepatic metabolism in idiosyncratic drug-induced liver injury.Evaluation of drug-induced injury and human response in precision-cut tissue slices.Recent advances in proteomics and cancer biomarker discovery.SEURAT-1 liver gold reference compounds: a mechanism-based review.Characterization of dasatinib and its structural analogs as CYP3A4 mechanism-based inactivators and the proposed bioactivation pathways.Effect of Disease Pathologies on Transporter Expression and Function.Characterization of drug metabolites and cytotoxicity assay simultaneously using an integrated microfluidic device.Modeling Epoxidation of Drug-like Molecules with a Deep Machine Learning Network.Liver Effects of Clinical Drugs Differentiated in Human Liver Slices.CSH guidelines for the diagnosis and treatment of drug-induced liver injuryA new approach on methamphetamine-induced hepatotoxicity: involvement of mitochondrial dysfunction.Non-clinical evaluation of the metabolism, pharmacokinetics and excretion of S-777469, a new cannabinoid receptor 2 selective agonist.Toxicological role of an acyl glucuronide metabolite in diclofenac-induced acute liver injury in mice.Integration of genome-scale metabolic networks into whole-body PBPK models shows phenotype-specific cases of drug-induced metabolic perturbation.Use of proteomics for the discovery of early markers of drug toxicityTransporters in Drug Discovery
P2860
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P2860
Drug metabolite profiling and elucidation of drug-induced hepatotoxicity.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Drug metabolite profiling and elucidation of drug-induced hepatotoxicity.
@en
type
label
Drug metabolite profiling and elucidation of drug-induced hepatotoxicity.
@en
prefLabel
Drug metabolite profiling and elucidation of drug-induced hepatotoxicity.
@en
P2860
P356
P1476
Drug metabolite profiling and elucidation of drug-induced hepatotoxicity.
@en
P2093
P2860
P304
P356
10.1517/17425255.3.3.407
P407
P577
2007-06-01T00:00:00Z