Studies on the mechanism of action of prekinamycin, a member of the diazoparaquinone family of natural products: evidence for both sp2 radical and orthoquinonemethide intermediates.
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Diazo Compounds: Versatile Tools for Chemical BiologyThe cytotoxicity of (-)-lomaiviticin A arises from induction of double-strand breaks in DNA.Asymmetric total synthesis of the epoxykinamycin FL-120 B'.Analysis of diazofluorene DNA binding and damaging activity: DNA cleavage by a synthetic monomeric diazofluoreneMechanism of the cytotoxicity of the diazoparaquinone antitumor antibiotic kinamycin FIdentification of Alp1U and Lom6 as epoxy hydrolases and implications for kinamycin and lomaiviticin biosynthesisDevelopment of enantioselective synthetic routes to (-)-kinamycin F and (-)-lomaiviticin aglycon.11-Step enantioselective synthesis of (-)-lomaiviticin aglyconThe diazofluorene antitumor antibiotics: structural elucidation, biosynthetic, synthetic, and chemical biological studies.Angucyclines: Biosynthesis, mode-of-action, new natural products, and synthesis.Mechanism of Nucleophilic Activation of (-)-Lomaiviticin A.Heteroatom-Heteroatom Bond Formation in Natural Product Biosynthesis.Diels-Alder reactions using 4,7-dioxygenated indanones as dienophiles for regioselective construction of oxygenated 2,3-dihydrobenz[f]indenone skeleton.Enantioselective synthesis of the lomaiviticin aglycon full carbon skeleton reveals remarkable remote substituent effects during the dimerization event.The Mechanism of Action of (-)-Lomaiviticin A.Weapons in disguise--activating mechanisms and protecting group chemistry in nature.
P2860
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P2860
Studies on the mechanism of action of prekinamycin, a member of the diazoparaquinone family of natural products: evidence for both sp2 radical and orthoquinonemethide intermediates.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Studies on the mechanism of ac ...... oquinonemethide intermediates.
@en
type
label
Studies on the mechanism of ac ...... oquinonemethide intermediates.
@en
prefLabel
Studies on the mechanism of ac ...... oquinonemethide intermediates.
@en
P2860
P356
P1476
Studies on the mechanism of ac ...... oquinonemethide intermediates.
@en
P2093
Ken S Feldman
Kyle J Eastman
P2860
P304
12562-12573
P356
10.1021/JA0642616
P407
P577
2006-09-01T00:00:00Z