about
Aging: progressive decline in fitness due to the rising deleteriome adjusted by genetic, environmental, and stochastic processesBefore senescence: the evolutionary demography of ontogenesisIndividual fitness and phenotypic selection in age-structured populations with constant growth rates.Aging in a long-lived clonal tree.The new biology of ageing.Mutation accumulation may be a minor force in shaping life history traits.Integrating evolutionary and molecular genetics of aging.Mutation accumulation may only be a minor force in shaping life-history traits, even when reproduction is sexual.Plasticity and rectangularity in survival curves.Paradoxical physiological transitions from aging to late life in DrosophilaThe two halves of U-shaped mortalityEvolution of male life histories and age-dependent sexual signals under female choice.Why organisms age: Evolution of senescence under positive pleiotropy?Pleiotropy, constraint, and modularity in the evolution of life histories: insights from genomic analyses.Beta human papillomavirus E6 expression inhibits stabilization of p53 and increases tolerance of genomic instability.Density-dependence interacts with extrinsic mortality in shaping life histories.Evolution of aging: individual life history trade-offs and population heterogeneity account for mortality patterns across species.Maladaptation as a source of senescence in habitats variable in space and time.The human post-fertile lifespan in comparative evolutionary context.Reduced lifespan and increased ageing driven by genetic drift in small populations.Significance of cellular senescence in aging and cancer.Evolutionary demography and quantitative genetics: age-specific survival as a threshold trait.What can genetic variation tell us about the evolution of senescence?
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
A theory of age-dependent mutation and senescence.
@en
type
label
A theory of age-dependent mutation and senescence.
@en
prefLabel
A theory of age-dependent mutation and senescence.
@en
P2860
P1433
P1476
A theory of age-dependent mutation and senescence
@en
P2093
Jacob A Moorad
P2860
P304
P356
10.1534/GENETICS.108.088526
P407
P577
2008-07-27T00:00:00Z