NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways. - Wikidata - awgldk - TriplyDB

NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways.

NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways.

http://www.wikidata.org/entity/Q36839608

about

Novel role of PKR in inflammasome activation and HMGB1 release Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1α and IL-1β Many stimuli pull the necrotic trigger, an overview Role of the inflammasome, IL-1β, and IL-18 in bacterial infections Klebsiella pneumoniae: Going on the Offense with a Strong Defense Immune Homeostasis in Epithelial Cells: Evidence and Role of Inflammasome Signaling Reviewed Immune-regulatory mechanisms in systemic autoimmune and rheumatic diseases Regulation of HMGB1 release by inflammasomes Investigating the role of nucleotide-binding oligomerization domain-like receptors in bacterial lung infection Regulation of inflammasome signaling An Update on PYRIN Domain-Containing Pattern Recognition Receptors: From Immunity to Pathology NLRP3 inflammasome and its inhibitors: a review Inflammasomes and Their Role in Innate Immunity of Sexually Transmitted Infections The inflammasome: an emerging therapeutic oncotarget for cancer prevention The NLRP3 inflammasome in pathogenic particle and fibre-associated lung inflammation and diseases Extracellular HMGB1 regulates multi-walled carbon nanotube-induced inflammation in vivo ATP binding by NLRP7 is required for inflammasome activation in response to bacterial lipopeptides Genetically manipulated mouse models of lung disease: potential and pitfalls Autophagy deficiency in macrophages enhances NLRP3 inflammasome activity and chronic lung disease following silica exposure The PYRIN Domain-only Protein POP1 Inhibits Inflammasome Assembly and Ameliorates Inflammatory Disease Curcumin: a double hit on malignant mesothelioma Characterization of NLRP12 during the development of allergic airway disease in mice Characterization of NLRP12 during the in vivo host immune response to Klebsiella pneumoniae and Mycobacterium tuberculosis NLRP1-dependent pyroptosis leads to acute lung injury and morbidity in mice ADAM10 Cell Surface Expression but Not Activity Is Critical for Staphylococcus aureus α-Hemolysin-Mediated Activation of the NLRP3 Inflammasome in Human Monocytes Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β Phagolysosome Acidification is Required for Silica and Engineered Nanoparticle-induced Lysosome Membrane Permeabilization and Resultant NLRP3 Inflammasome Activity The Yersinia Type III secretion effector YopM Is an E3 ubiquitin ligase that induced necrotic cell death by targeting NLRP3 Differences in Inflammatory Response Induced by Two Representatives of Clades of the Pandemic ST258 Klebsiella pneumoniae Clonal Lineage Producing KPC-Type Carbapenemases.Receptor for advanced glycation end products (RAGE) on iNKT cells mediates lung ischemia-reperfusion injury.Complementary induction of immunogenic cell death by oncolytic parvovirus H-1PV and gemcitabine in pancreatic cancer Dnase1L3 Regulates Inflammasome-Dependent Cytokine Secretion.The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis.Alarmins, inflammasomes and immunity.Human macrophages infected with a high burden of ESAT-6-expressing M. tuberculosis undergo caspase-1- and cathepsin B-independent necrosis Dendritic cells in systemic lupus erythematosus High mobility group box-1 (HMGB1) participates in the pathogenesis of alcoholic liver disease (ALD).The utilization of oropharyngeal intratracheal PAMP administration and bronchoalveolar lavage to evaluate the host immune response in mice.Reactive oxygen species regulate caspase-11 expression and activation of the non-canonical NLRP3 inflammasome during enteric pathogen infection.α7 nicotinic acetylcholine receptor signaling inhibits inflammasome activation by preventing mitochondrial DNA release.

P2860

Q24293509-A6131F95-4D87-480B-BA62-F682BD44C97D Q24603082-FA067425-5A3F-4208-9EAA-0BD99D636EE6 Q24613714-20340D7B-6A1C-4E0C-A33C-80DDA9824684 Q24627445-8429609D-4776-40E0-A3D2-CB25E11DED4A Q26745802-2180C552-02D6-4580-86AB-38558715BFD2 Q26781987-74F2CF17-3EA1-4AA9-9606-65518CB17940 Q26823714-35CD17C2-BEE3-4452-9C0D-09D81A0B24D4 Q26829877-D0D763CC-4EF6-44FB-9BFF-E49DC1DA439F Q26863593-FCE3A91B-DFD4-4CFC-9F97-C18A432B221E Q26996605-37013ACD-B418-41B2-AFFF-957B2BDBF3C0 Q27004333-028F5C24-DF22-4E24-B121-915D75FE125C Q27023333-8267A856-5DE4-4F93-9423-DAC6A425F670 Q28067011-E1A4AC15-F108-4E16-A01E-FEE8AC746013 Q28076914-582977A3-087D-415B-A903-2D7F0CAAE8C2 Q28080249-012A1BAC-ECD4-4177-8CA5-163F8DD4A2C1 Q28387701-F1A55AF9-D90A-43BB-A58E-F7A9D4D0E6C4 Q28388318-73039F9E-DF50-4394-822C-DC5586BCC61B Q28388821-9679E784-E586-4514-BC2E-B812552E5F5C Q28391150-4AB4780B-A786-45DF-BDC2-941028571812 Q28395210-B41DD670-4707-4934-8AFB-A6FD6D802025 Q28397518-616C246C-20F4-4661-BF6D-BF019FB59D7D Q28479021-588B1775-A70E-419E-AE06-7DB3C4297193 Q28486059-5A9E9D4F-D141-4434-B5BE-D25380D8A89D Q28508483-333DBCA0-D1B9-4489-88A0-DD93811C8303 Q28834038-9A681A48-C241-4F35-806B-7DC681E01B31 Q29030555-BC700F15-ECBB-455D-BC86-A4C2D3F3E75B Q29247974-FB8ABA82-679A-4451-9237-262294A3812D Q29248184-F2E1AC2E-F6A1-4B3F-8DEB-76A197D0468A Q30397403-239CF1DD-71A0-4E66-B28F-F231060CD823 Q30410928-90710E6C-6FFE-4DA1-9A15-EFD90AEFD22B Q33602876-0704F602-AB0F-4C7E-B67F-93F81FAA141C Q33645722-E11BF4F8-1A3F-40F2-A8A2-86335AA43C0D Q33732343-19679697-BF42-49E0-B0D9-06F19AFDF540 Q33817302-E907DB18-AB83-46C0-816D-4DC283644F2D Q33921372-7DE3D5E4-9BFD-4EC0-872D-E4C293E55064 Q33941433-5BF1B34E-B68F-44CF-A5EE-92C6A2E9294C Q34044574-22E1B2CC-FCA2-4B48-893C-2B99D40F4918 Q34165189-468D6CE2-6678-4434-9871-4FDC027429EC Q34257920-812632AC-482E-48BB-8F89-21CAC3EE1C4B Q34420936-3A03D512-E2B5-4F13-8B7D-1578C81EFED4

P2860

NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways.

http://www.wikidata.org/entity/Q36839608

description

2009 nî lūn-bûn

@nan

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

2009年论文

@zh

2009年论文

@zh-cn

name

NLRP3 (NALP3, Cryopyrin) facil ...... ent and -independent pathways.

@en

type

label

NLRP3 (NALP3, Cryopyrin) facil ...... ent and -independent pathways.

@en

prefLabel

NLRP3 (NALP3, Cryopyrin) facil ...... ent and -independent pathways.

@en

P1433

Q36839608-E65679FE-B324-4E68-9A43-7C3E26EB7827

P1476

Q36839608-41112DB3-1339-4501-A645-4621B9B202B4

P2093

Q36839608-3993C6F9-4C37-4624-B8EF-8F305EA6CFBB

Q36839608-4513BED8-6EAB-4CCB-8C92-D9FC9DA733B5

Q36839608-69AFDDEF-5BBA-4B14-96E8-D60ECA33AB8B

Q36839608-6C21398E-4566-4C66-9592-35064B9B521F

Q36839608-7DAC906B-9BA1-40D6-8100-51435CA5FC65

Q36839608-96AC13EF-1C88-4533-A067-7118B06F97B3

Q36839608-BF24DD2D-816F-4918-B411-B973B5E8A711

P2860

Q36839608-012131A1-E8CE-43E6-AFAB-427E6A18E8F7

Q36839608-02BE460E-6E7E-480F-819D-0C009DDB7B63

Q36839608-051504B8-1B80-4BC6-93A0-E4CC9A5A45D2

Q36839608-08329380-BC13-4BAD-A6C5-CB0491909F93

Q36839608-1176BE24-DABD-412D-9D4B-BB728A175895

Q36839608-118FE550-9D4C-4306-8236-B41AD90D4C15

Q36839608-1420252A-CAA2-48DA-891C-40BAA53A400D

Q36839608-1DCA0758-6849-4999-BCFD-3BACD8F2FC7B

Q36839608-27D20F73-A286-490D-9901-D4EC63000D3E

Q36839608-298598D2-E394-41D6-A392-9E6515428857

P304

Q36839608-EDBB3B8A-B7F0-4A1A-BD5B-4C08BF5AF4AB

P31

Q36839608-51829B84-2B0E-4A9B-B90F-A228C432D113

P356

Q36839608-E963E8B4-C387-406B-B74C-D4EBC0928C36

P407

Q36839608-42287E43-C21D-4255-878D-026B052614FB

P433

Q36839608-D04D3AC6-9BE8-40ED-B68E-1B34FB803921

P478

Q36839608-8576CC85-A458-4779-AD66-932B70D98A34

P50

Q36839608-02567B3F-3C06-4FE9-A44F-B111AB21A968

P577

Q36839608-6EACC2A6-0AD4-4202-8A82-04D20DE18E73

P5875

Q36839608-F667AF21-D890-4525-A5B5-B37BB71EA5F4

P698

Q36839608-938FBD6A-C99D-41FB-86CF-89A47AFA8839

P921

Q36839608-33E5A61B-4350-41EC-950C-C08AA09DFB2F

P932

Q36839608-253360C5-816A-488B-A3BC-84090665580D

P356

JIMMUNOL.0900138

P1433

Journal of Immunology

P1476

NLRP3 (NALP3, Cryopyrin) facil ...... dent and -independent pathways

@en

P2093

Debra J Taxman

http://www.w3.org/2001/XMLSchema#string

Irving C Allen

http://www.w3.org/2001/XMLSchema#string

Jenny P-Y Ting

http://www.w3.org/2001/XMLSchema#string

Joseph A Duncan

http://www.w3.org/2001/XMLSchema#string

Max Tze-Han Huang

http://www.w3.org/2001/XMLSchema#string

Stephen B Willingham

http://www.w3.org/2001/XMLSchema#string

Willie June Brickey

http://www.w3.org/2001/XMLSchema#string

P2860

Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes

Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases

The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals

The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

The NLR gene family: a standard nomenclature

Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1

P304

2008-2015

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.4049/JIMMUNOL.0900138

http://www.w3.org/2001/XMLSchema#string

P407

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

183

http://www.w3.org/2001/XMLSchema#string

P50

Dan T Bergstralh

P577

2009-07-08T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

26656229

http://www.w3.org/2001/XMLSchema#string

P698

19587006

http://www.w3.org/2001/XMLSchema#string

P921

P932

3652593

http://www.w3.org/2001/XMLSchema#string