In silico pharmacology for drug discovery: methods for virtual ligand screening and profiling.
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De novo discovery of serotonin N-acetyltransferase inhibitorsComputerized techniques pave the way for drug-drug interaction prediction and interpretationOne for All? Hitting Multiple Alzheimer's Disease Targets with One DrugModeling-Enabled Systems Nutritional ImmunologyMicrobial Biotransformation to Obtain New AntifungalsComputational methods in drug discoveryDrug repurposing and human parasitic protozoan diseasesAdvances in computationally modeling human oral bioavailabilityBCL::Conf: small molecule conformational sampling using a knowledge based rotamer libraryGPURFSCREEN: a GPU based virtual screening tool using random forest classifierBinding of protein kinase inhibitors to synapsin I inferred from pair-wise binding site similarity measurementsInhibitors of Helicobacter pylori protease HtrA found by 'virtual ligand' screening combat bacterial invasion of epitheliaA chemocentric approach to the identification of cancer targetsEnhancing hit identification in Mycobacterium tuberculosis drug discovery using validated dual-event Bayesian modelsOpen Source Bayesian Models. 1. Application to ADME/Tox and Drug Discovery DatasetsCollaboration for rare disease drug discovery researchDispensing processes impact apparent biological activity as determined by computational and statistical analyses.Data mining of solubility parameters for computational prediction of drug-excipient miscibility.Polypharmacology in Precision Oncology: Current Applications and Future ProspectsUse of big data in drug development for precision medicine.Prediction of new drug indications based on clinical data and network modularity.The toxicity data landscape for environmental chemicals.Applications of integrated data mining methods to exploring natural product space for acetylcholinesterase inhibitors.Toward better drug repositioning: prioritizing and integrating existing methods into efficient pipelines.Anti-non-Gal-specific combination treatment with an anti-idiotypic Ab and an inhibitory small molecule mitigates the xenoantibody response.Understanding nuclear receptors using computational methods.The importance of discerning shape in molecular pharmacology.Drug repositioning for enzyme modulator based on human metabolite-likeness.Recent application of analytical methods to phase I and phase II drugs development: a review.Combination of biological screening in a cellular model of viral latency and virtual screening identifies novel compounds that reactivate HIV-1Drug repositioning using in silico compound profiling.Structural basis for computational screening of non-steroidal androgen receptor ligands.Sanjeevini: a freely accessible web-server for target directed lead molecule discoveryVirtual screening of chemical libraries for drug discovery.[Small compounds libraries: a research tool for chemical biology].Drug repurposing: mining protozoan proteomes for targets of known bioactive compounds.In Silico Augmentation of the Drug Development Pipeline: Examples from the study of Acute Inflammation.A Discovery Funnel for Nucleic Acid Binding Drug CandidatesDeficiencies in the reporting of VD and t(1/2) in the FDA approved chemotherapy drug inserts.Novel anti-plasmodial hits identified by virtual screening of the ZINC database.
P2860
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P2860
In silico pharmacology for drug discovery: methods for virtual ligand screening and profiling.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
In silico pharmacology for dru ...... igand screening and profiling.
@en
type
label
In silico pharmacology for dru ...... igand screening and profiling.
@en
prefLabel
In silico pharmacology for dru ...... igand screening and profiling.
@en
P2860
P356
P1476
In silico pharmacology for dru ...... igand screening and profiling.
@en
P2093
P2860
P356
10.1038/SJ.BJP.0707305
P407
P577
2007-06-04T00:00:00Z