Synthesis and biological activity of a gemcitabine phosphoramidate prodrug - Wikidata - awgldk - TriplyDB

Synthesis and biological activity of a gemcitabine phosphoramidate prodrug

Synthesis and biological activity of a gemcitabine phosphoramidate prodrug

http://www.wikidata.org/entity/Q36841942

about

Synthesis of nucleoside phosphate and phosphonate prodrugs Cellular pharmacology of multi- and duplex drugs consisting of ethynylcytidine and 5-fluoro-2'-deoxyuridine.TFAA/H3PO4 mediated unprecedented N-acylation of carbazoles leading to small molecules possessing anti-proliferative activities against cancer cells.Synthesis and in vitro evaluation of novel lipophilic monophosphorylated gemcitabine derivatives and their nanoparticles.Deoxyuridine analog nucleotides in deoxycytidine analog treatment: secondary active metabolites?Lipophilic prodrugs and formulations of conventional (deoxy)nucleoside and fluoropyrimidine analogs in cancer.Overcoming nucleoside analog chemoresistance of pancreatic cancer: a therapeutic challenge.Do hENT1 and RRM1 predict the clinical benefit of gemcitabine in pancreatic cancer?Synthesis and evaluation of stable substrate analogs as potential modulators of cyclodiphosphate synthase IspF.Efficient synthesis of exo-N-carbamoyl nucleosides: application to the synthesis of phosphoramidate prodrugs.Ligand/PTC-free intramolecular Heck reaction: synthesis of pyrroloquinoxalines and their evaluation against PDE4/luciferase/oral cancer cell growth in vitro and zebrafish in vivo.Pancreatic Cancer Chemoresistance to Gemcitabine.Vitamin E Phosphate Nucleoside Prodrugs: A Platform for Intracellular Delivery of Monophosphorylated Nucleosides.

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P2860

Synthesis and biological activity of a gemcitabine phosphoramidate prodrug

http://www.wikidata.org/entity/Q36841942

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

2007年论文

@zh

2007年论文

@zh-cn

name

Synthesis and biological activity of a gemcitabine phosphoramidate prodrug

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type

label

Synthesis and biological activity of a gemcitabine phosphoramidate prodrug

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prefLabel

Synthesis and biological activity of a gemcitabine phosphoramidate prodrug

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Journal of Medicinal Chemistry

P1476

Synthesis and biological activity of a gemcitabine phosphoramidate prodrug

@en

P2093

Godefridus J Peters

http://www.w3.org/2001/XMLSchema#string

Jennifer Sigmond

http://www.w3.org/2001/XMLSchema#string

Richard F Borch

http://www.w3.org/2001/XMLSchema#string

Weidong Wu

http://www.w3.org/2001/XMLSchema#string

P2860

Role of deoxycytidine kinase (dCK) activity in gemcitabine's radioenhancement in mice and human cell lines in vitro

Activation mechanisms of nucleoside phosphoramidate prodrugs.

Synthesis and biological activity of novel 5-fluoro-2'-deoxyuridine phosphoramidate prodrugs.

Role of antimetabolites of purine and pyrimidine nucleotide metabolism in tumor cell differentiation.

Pronucleotides: toward the in vivo delivery of antiviral and anticancer nucleotides.

Determinants of resistance to 2',2'-difluorodeoxycytidine (gemcitabine).

The potential of nucleotide analogs as inhibitors of retroviruses and tumors.

Gemcitabine: metabolism, mechanisms of action, and self-potentiation.

Minireview: nucleotide prodrugs.

Synthesis and biological evaluation of a cytarabine phosphoramidate prodrug.

P304

3743-3746

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scholarly article

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10.1021/JM070269U

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15

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50

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2007-06-29T00:00:00Z

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