Tighter binding of HIV reverse transcriptase to RNA-DNA versus DNA-DNA results mostly from interactions in the polymerase domain and requires just a small stretch of RNA-DNA.
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Structural and Binding Analysis of Pyrimidinol Carboxylic Acid and N-Hydroxy Quinazolinedione HIV-1 RNase H InhibitorsStructural analysis of monomeric retroviral reverse transcriptase in complex with an RNA/DNA hybridStructures of HIV-1 RT-RNA/DNA ternary complexes with dATP and nevirapine reveal conformational flexibility of RNA/DNA: insights into requirements for RNase H cleavageDuplex structural differences and not 2'-hydroxyls explain the more stable binding of HIV-reverse transcriptase to RNA-DNA versus DNA-DNA.HIV-1 Ribonuclease H: Structure, Catalytic Mechanism and Inhibitors.Structural probing of the HIV-1 polypurine tract RNA:DNA hybrid using classic nucleic acid ligands.Preferred sequences within a defined cleavage window specify DNA 3' end-directed cleavages by retroviral RNases HEnzymatic Activities of RNase H Domains of HIV-1 Reverse Transcriptase with Substrate Binding Domains of Bacterial RNases H1 and H2.RNase H sequence preferences influence antisense oligonucleotide efficiency.Transcriptional inaccuracy threshold attenuates differences in RNA-dependent DNA synthesis fidelity between retroviral reverse transcriptases.
P2860
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P2860
Tighter binding of HIV reverse transcriptase to RNA-DNA versus DNA-DNA results mostly from interactions in the polymerase domain and requires just a small stretch of RNA-DNA.
description
2006 nî lūn-bûn
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2006年の論文
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name
Tighter binding of HIV reverse ...... st a small stretch of RNA-DNA.
@en
type
label
Tighter binding of HIV reverse ...... st a small stretch of RNA-DNA.
@en
prefLabel
Tighter binding of HIV reverse ...... st a small stretch of RNA-DNA.
@en
P2860
P356
P1433
P1476
Tighter binding of HIV reverse ...... st a small stretch of RNA-DNA.
@en
P2093
Jeffrey J DeStefano
William P Bohlayer
P2860
P304
P356
10.1021/BI051770W
P407
P577
2006-06-01T00:00:00Z