Influenza virus-susceptible mice carry Mx genes with a large deletion or a nonsense mutation
about
The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage.Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTPResistance to influenza virus and vesicular stomatitis virus conferred by expression of human MxA proteinThe role of host genetics in susceptibility to influenza: a systematic reviewModeling host genetic regulation of influenza pathogenesis in the collaborative crossHuman MxA protein protects mice lacking a functional alpha/beta interferon system against La crosse virus and other lethal viral infectionsA nonsense mutation in the gene encoding 2'-5'-oligoadenylate synthetase/L1 isoform is associated with West Nile virus susceptibility in laboratory miceThe Marmoset Model of GB Virus B Infections: Adaptation to Host Phenotypic VariationInfluenza virus NS1 protein counteracts PKR-mediated inhibition of replication.Host genetic determinants of influenza pathogenicity.The Mx1 gene protects mice against the pandemic 1918 and highly lethal human H5N1 influenza viruses.Molecular determinants of influenza virus pathogenesis in mice.Influenza A virus strains differ in sensitivity to the antiviral action of Mx-GTPaseEmerging influenza.The nucleoprotein of newly emerged H7N9 influenza A virus harbors a unique motif conferring resistance to antiviral human MxA.Heterosubtypic immunity to influenza A virus: where do we stand?Pathogenesis of 1918 pandemic and H5N1 influenza virus infections in a guinea pig model: antiviral potential of exogenous alpha interferon to reduce virus sheddingExperimental infection of pigs with the human 1918 pandemic influenza virusLethal dissemination of H5N1 influenza virus is associated with dysregulation of inflammation and lipoxin signaling in a mouse model of infection.Pigs with Severe Combined Immunodeficiency Are Impaired in Controlling Influenza A Virus Infection.In vivo evasion of MxA by avian influenza viruses requires human signature in the viral nucleoprotein.Molecular signatures associated with Mx1-mediated resistance to highly pathogenic influenza virus infection: mechanisms of survivalInterferon-inducible protein Mx1 inhibits influenza virus by interfering with functional viral ribonucleoprotein complex assemblyPrioritizing genes responsible for host resistance to influenza using network approachesInterferon-lambda contributes to innate immunity of mice against influenza A virus but not against hepatotropic viruses.Host genetic background strongly influences the response to influenza a virus infections.Sendai virus and simian virus 5 block activation of interferon-responsive genes: importance for virus pathogenesisPathogenesis of a model gammaherpesvirus in a natural hostMx1 reveals innate pathways to antiviral resistance and lethal influenza diseaseThe role of interferon in influenza virus tissue tropism.The role of alpha/beta and gamma interferons in development of immunity to influenza A virus in miceInfluenza-induced production of interferon-alpha is defective in geriatric individuals.Innate immunity to influenza virus infection.Host genetic risk factors for West Nile virus infection and disease progression.Genomic profiling of collaborative cross founder mice infected with respiratory viruses reveals novel transcripts and infection-related strain-specific gene and isoform expression.Temporal and spatial resolution of type I and III interferon responses in vivo.Human IRGM gene "to be or not to be".Lethal H5N1 influenza viruses escape host anti-viral cytokine responses.Low-pathogenic avian influenza viruses in wild house mice.Hantaan virus infection causes an acute neurological disease that is fatal in adult laboratory mice.
P2860
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P2860
Influenza virus-susceptible mice carry Mx genes with a large deletion or a nonsense mutation
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Influenza virus-susceptible mi ...... eletion or a nonsense mutation
@en
type
label
Influenza virus-susceptible mi ...... eletion or a nonsense mutation
@en
prefLabel
Influenza virus-susceptible mi ...... eletion or a nonsense mutation
@en
P2093
P2860
P356
P1476
Influenza virus-susceptible mi ...... eletion or a nonsense mutation
@en
P2093
P2860
P304
P356
10.1128/MCB.8.10.4518
P407
P577
1988-10-01T00:00:00Z