Mechanism of auxiliary subunit modulation of neuronal alpha1E calcium channels
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A specific tryptophan in the I-II linker is a key determinant of beta-subunit binding and modulation in Ca(V)2.3 calcium channelsDistinctive modulatory effects of five human auxiliary beta2 subunit splice variants on L-type calcium channel gating.Functional properties of a new voltage-dependent calcium channel alpha(2)delta auxiliary subunit gene (CACNA2D2)Novel functional properties of Ca(2+) channel beta subunits revealed by their expression in adult rat heart cellsStructure-function of proteins interacting with the α1 pore-forming subunit of high-voltage-activated calcium channelsGating deficiency in a familial hemiplegic migraine type 1 mutant P/Q-type calcium channelThe alpha2delta auxiliary subunit reduces affinity of omega-conotoxins for recombinant N-type (Cav2.2) calcium channelsBARP suppresses voltage-gated calcium channel activity and Ca2+-evoked exocytosisThe junctional SR protein JP-45 affects the functional expression of the voltage-dependent Ca2+ channel Cav1.1The ß subunit of voltage-gated Ca2+ channelsDeterminants of the voltage dependence of G protein modulation within calcium channel beta subunits.Functional modularity of the beta-subunit of voltage-gated Ca2+ channels.Membrane-associated guanylate kinase-like properties of beta-subunits required for modulation of voltage-dependent Ca2+ channelsContrasting the roles of the I-II loop gating brake in CaV3.1 and CaV3.3 calcium channels.The N-terminal domain tethers the voltage-gated calcium channel β2e-subunit to the plasma membrane via electrostatic and hydrophobic interactionsThe voltage dependence of gating currents of the neuronal CA(v)3.3 channel is determined by the gating brake in the I-II loopAtypical properties of a conventional calcium channel beta subunit from the platyhelminth Schistosoma mansoni.Diversity and developmental expression of L-type calcium channel beta2 proteins and their influence on calcium current in murine heart.Molecular endpoints of Ca2+/calmodulin- and voltage-dependent inactivation of Ca(v)1.3 channelsNeuronal distribution and functional characterization of the calcium channel alpha2delta-2 subunit.N-type calcium channel inactivation probed by gating-current analysis.Involvement of the carboxy-terminus region of the dihydropyridine receptor beta1a subunit in excitation-contraction coupling of skeletal muscleCritical determinants of Ca(2+)-dependent inactivation within an EF-hand motif of L-type Ca(2+) channels.Variable ratio of permeability to gating charge of rBIIA sodium channels and sodium influx in Xenopus oocytes.Calcium channel auxiliary α2δ and β subunits: trafficking and one step beyond.Differential occurrence of reluctant openings in G-protein-inhibited N- and P/Q-type calcium channelsOverexpressed Ca(v)beta3 inhibits N-type (Cav2.2) calcium channel currents through a hyperpolarizing shift of ultra-slow and closed-state inactivationThe guanylate kinase domain of the beta-subunit of voltage-gated calcium channels suffices to modulate gating.Voltage-gated calcium channels and their auxiliary subunits: physiology and pathophysiology and pharmacologyEngineering proteins for custom inhibition of Ca(V) channels.Structure and function of the β subunit of voltage-gated Ca²⁺ channels.Regulation of voltage-dependent calcium channels by RGK proteins.C-terminal modulatory domain controls coupling of voltage-sensing to pore opening in Cav1.3 L-type Ca(2+) channels.omega-conotoxin GVIA alters gating charge movement of N-type (CaV2.2) calcium channels.Proteolytic cleavage of the voltage-gated Ca2+ channel alpha2delta subunit: structural and functional features.Ca(2+) channel inactivation heterogeneity reveals physiological unbinding of auxiliary beta subunits.Calcium flux in neuroblastoma cells is a coupling mechanism between non-genomic and genomic modes of estrogens.A single CaVbeta can reconstitute both trafficking and macroscopic conductance of voltage-dependent calcium channels.Glycosylation of asparagines 136 and 184 is necessary for the alpha2delta subunit-mediated regulation of voltage-gated Ca2+ channels.Auxiliary subunit regulation of high-voltage activated calcium channels expressed in mammalian cells.
P2860
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P2860
Mechanism of auxiliary subunit modulation of neuronal alpha1E calcium channels
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Mechanism of auxiliary subunit modulation of neuronal alpha1E calcium channels
@en
type
label
Mechanism of auxiliary subunit modulation of neuronal alpha1E calcium channels
@en
prefLabel
Mechanism of auxiliary subunit modulation of neuronal alpha1E calcium channels
@en
P2093
P2860
P356
P1476
Mechanism of auxiliary subunit modulation of neuronal alpha1E calcium channels
@en
P2093
P2860
P304
P356
10.1085/JGP.112.2.125
P577
1998-08-01T00:00:00Z