Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer. - Wikidata - awgldk - TriplyDB

Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer.

Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer.

http://www.wikidata.org/entity/Q36852678

about

The NF-κB Pathway and Cancer Stem Cells Hallmarks of glycosylation in cancer Cytokine-Induced Modulation of Colorectal Cancer The Contrived Mutant p53 Oncogene - Beyond Loss of Functions Chemoresistance and Cancer-Related Inflammation: Two Hallmarks of Cancer Connected by an Atypical Link, PKCζ Multifocal epithelial tumors and field cancerization: stroma as a primary determinant The therapeutic value of targeting inflammation in gastrointestinal cancers The role of tumor suppressor p53 in the antioxidant defense and metabolism The laminin response in inflammatory bowel disease: protection or malignancy?Caught in the cross fire: p53 in inflammation.Drug Discovery via Human-Derived Stem Cell Organoids Gain of function of mutant p53: R282W on the peak?Disruptive environmental chemicals and cellular mechanisms that confer resistance to cell death Mutant p53 Protein and the Hippo Transducers YAP and TAZ: A Critical Oncogenic Node in Human Cancers.ShaoYao decoction ameliorates colitis-associated colorectal cancer by downregulating proinflammatory cytokines and promoting epithelial-mesenchymal transition.NF-κB, an active player in human cancers.Ginsenoside Rg3 Inhibits Constitutive Activation of NF-κB Signaling in Human Breast Cancer (MDA-MB-231) Cells: ERK and Akt as Potential Upstream Targets.Roles of tumor suppressors in regulating tumor-associated inflammation.Methotrexate inhibits NF-κB activity via long intergenic (noncoding) RNA-p21 induction Epigenetic linkage of aging, cancer and nutrition.Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to regulate VEGFR2 in breast cancer cells Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression.Methotrexate-mediated inhibition of nuclear factor κB activation by distinct pathways in T cells and fibroblast-like synoviocytes.microRNAs: short non-coding bullets of gain of function mutant p53 proteins.The gut microbiota in mouse models of inflammatory bowel disease.NPC1L1 knockout protects against colitis-associated tumorigenesis in mice.Mutant p53 - Heat Shock Response Oncogenic Cooperation: A New Mechanism of Cancer Cell Survival.Mutual reinforcement of inflammation and carcinogenesis by the Helicobacter pylori CagA oncoprotein.Primed for cancer: Li Fraumeni Syndrome and the pre-cancerous niche Suppression of NF-κB and NF-κB-Regulated Gene Expression by Apigenin through IκBα and IKK Pathway in TRAMP Mice.Doxycycline Promotes Carcinogenesis & Metastasis via Chronic Inflammatory Pathway: An In Vivo Approach Computational Reconstruction of NFκB Pathway Interaction Mechanisms during Prostate Cancer.BAG2 promotes tumorigenesis through enhancing mutant p53 protein levels and function.IL-15 suppresses colitis-associated colon carcinogenesis by inducing antitumor immunity.Novel reversible selective inhibitor of nuclear export shows that CRM1 is a target in colorectal cancer cells.Gene and protein expression of O-GlcNAc-cycling enzymes in human laryngeal cancer.p53 amplifies Toll-like receptor 5 response in human primary and cancer cells through interaction with multiple signal transduction pathways STK4 regulates TLR pathways and protects against chronic inflammation-related hepatocellular carcinoma.Loss of Stromal IMP1 Promotes a Tumorigenic Microenvironment in the Colon.Prognostic impact of c-Rel nuclear expression and REL amplification and crosstalk between c-Rel and the p53 pathway in diffuse large B-cell lymphoma.

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P2860

Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer.

http://www.wikidata.org/entity/Q36852678

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2013年论文

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name

Mutant p53 prolongs NF-κB acti ...... -associated colorectal cancer.

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Mutant p53 prolongs NF-κB acti ...... -associated colorectal cancer.

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Mutant p53 prolongs NF-κB acti ...... -associated colorectal cancer.

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J.CCR.2013.03.022

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Mutant p53 prolongs NF-κB acti ...... n-associated colorectal cancer

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Aaron J Schetter

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Curtis C Harris

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Eli Pikarsky

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Guillermina Lozano

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Hilla Solomon

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Ioannis S Pateras

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Nitzan Rosenfeld

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Ohad Tarcic

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Steven Itzkowitz

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Sylvia Wilder

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P2860

Hallmarks of Cancer: The Next Generation

The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression

The first 30 years of p53: growing ever more complex

A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53

Lessons from hereditary colorectal cancer

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

Transcriptional and posttranscriptional regulation of angiopoietin-2 expression mediated by IGF and PDGF in vascular smooth muscle cells

Blinded by the Light: The Growing Complexity of p53

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

Inflammation meets cancer, with NF-κB as the matchmaker

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634-646

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10.1016/J.CCR.2013.03.022

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23680148

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colorectal cancer

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3657134

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