Mig6 is a sensor of EGF receptor inactivation that directly activates c-Abl to induce apoptosis during epithelial homeostasis
about
The role of small adaptor proteins in the control of oncogenic signalingr driven by tyrosine kinases in human cancerTargeting EGFR signalling in chronic lung disease: therapeutic challenges and opportunitiesDevelopmental programming mediated by complementary roles of imprinted Grb10 in mother and pupGene 33/Mig6 inhibits hexavalent chromium-induced DNA damage and cell transformation in human lung epithelial cellsRole of ABL family kinases in cancer: from leukaemia to solid tumoursAngiotensin II down-regulates nephrin-Akt signaling and induces podocyte injury: roleof c-Abl.Accelerated and increased joint damage in young mice with global inactivation of mitogen-inducible gene 6 after ligament and meniscus injury.The roles and regulation of multicellular rosette structures during morphogenesis.Mig6 haploinsufficiency protects mice against streptozotocin-induced diabetesMig-6 gene knockout induces neointimal hyperplasia in the vascular smooth muscle cell.Pathways driving the endocytosis of mutant and wild-type EGFR in cancer.The antitumorigenic function of EGFR in metastatic breast cancer is regulated by expression of Mig6.Loss of MIG6 Accelerates Initiation and Progression of Mutant Epidermal Growth Factor Receptor-Driven Lung Adenocarcinoma.Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6Nuclear Gene 33/Mig6 Regulates the DNA Damage Response through an ATM-dependent Mechanism.Single-cell RNA sequencing reveals an altered gene expression pattern as a result of CRISPR/cas9-mediated deletion of Gene 33/Mig6 and chronic exposure to hexavalent chromium in human lung epithelial cells.Microvesicle Cargo and Function Changes upon Induction of Cellular Transformation.Activated Cdc42-associated kinase 1 (Ack1) is required for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor recruitment to lipid rafts and induction of cell deathMutant p53 dictates the oncogenic activity of c-Abl in triple-negative breast cancers.A pervasive role for MIG6 in restraining cell proliferation.IBD candidate genes and intestinal barrier regulation.
P2860
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P2860
Mig6 is a sensor of EGF receptor inactivation that directly activates c-Abl to induce apoptosis during epithelial homeostasis
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Mig6 is a sensor of EGF recept ...... during epithelial homeostasis
@en
type
label
Mig6 is a sensor of EGF recept ...... during epithelial homeostasis
@en
prefLabel
Mig6 is a sensor of EGF recept ...... during epithelial homeostasis
@en
P2093
P2860
P50
P1433
P1476
Mig6 is a sensor of EGF recept ...... during epithelial homeostasis
@en
P2093
Emma Linderoth
Giulia Pilia
Howard Kendrick
Ingvar Ferby
Paula Suarez-Henriques
Sarah Hopkins
P2860
P304
P356
10.1016/J.DEVCEL.2012.08.001
P407
P577
2012-09-01T00:00:00Z