Partial activity is seen with many substitutions of highly conserved active site residues in human Pseudouridine synthase 1.
about
In Human Pseudouridine Synthase 1 (hPus1), a C-Terminal Helical Insert Blocks tRNA from Binding in the Same Orientation as in the Pus1 Bacterial Homologue TruA, Consistent with Their Different Target SelectivitiesThe mechanism of pseudouridine synthases from a covalent complex with RNA, and alternate specificity for U2605 versus U2604 between close homologsSteroid receptor RNA activator (SRA) modification by the human pseudouridine synthase 1 (hPus1p): RNA binding, activity, and atomic modelPseudouridine synthase 1: a site-specific synthase without strict sequence recognition requirementsPseudouridine: still mysterious, but never a fake (uridine)!Pseudouridine synthase 1 deficient mice, a model for Mitochondrial Myopathy with Sideroblastic Anemia, exhibit muscle morphology and physiology alterations.The Pseudouridine Synthases Proceed through a Glycal Intermediate.Role of forefinger and thumb loops in production of Ψ54 and Ψ55 in tRNAs by archaeal Pus10.Formation of a stalled early intermediate of pseudouridine synthesis monitored by real-time FRET.PUS1 isoform 2 transforms uridine residues to pseudouridine in the anticodon stems of tRNAsPUS1 isoform 1 transforms uridine-27; uridine-28 yielding pseudouridine in tRNA(Lys;Ser)
P2860
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P2860
Partial activity is seen with many substitutions of highly conserved active site residues in human Pseudouridine synthase 1.
description
2008 nî lūn-bûn
@nan
2008年の論文
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2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
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2008年论文
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name
Partial activity is seen with ...... uman Pseudouridine synthase 1.
@en
type
label
Partial activity is seen with ...... uman Pseudouridine synthase 1.
@en
prefLabel
Partial activity is seen with ...... uman Pseudouridine synthase 1.
@en
P2093
P2860
P356
P1433
P1476
Partial activity is seen with ...... uman Pseudouridine synthase 1.
@en
P2093
Bryan S Sibert
Jeffrey R Patton
Nathan Fischel-Ghodsian
P2860
P304
P356
10.1261/RNA.984508
P407
P577
2008-07-22T00:00:00Z