Alcohol and PRAS40 knockdown decrease mTOR activity and protein synthesis via AMPK signaling and changes in mTORC1 interaction.
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Proteomic approaches and identification of novel therapeutic targets for alcoholismInhibition of glycogen synthase kinase 3[beta] activity with lithium in vitro attenuates sepsis-induced changes in muscle protein turnoverAlcohol-induced autophagy contributes to loss in skeletal muscle mass.Moderate alcohol induces stress proteins HSF1 and hsp70 and inhibits proinflammatory cytokines resulting in endotoxin tolerance.Deptor knockdown enhances mTOR Activity and protein synthesis in myocytes and ameliorates disuse muscle atrophy.The mechanism of insulin-stimulated 4E-BP protein binding to mammalian target of rapamycin (mTOR) complex 1 and its contribution to mTOR complex 1 signalingImipramine blocks ethanol-induced ASMase activation, ceramide generation, and PP2A activation, and ameliorates hepatic steatosis in ethanol-fed miceRag GTPases and AMPK/TSC2/Rheb mediate the differential regulation of mTORC1 signaling in response to alcohol and leucine.Peroxisome proliferator-activated receptor agonist treatment of alcohol-induced hepatic insulin resistance.Mechanisms mediating the effects of alcohol and HIV anti-retroviral agents on mTORC1, mTORC2 and protein synthesis in myocytes.Alcohol-induced modulation of rictor and mTORC2 activity in C2C12 myoblasts.Adamts1 mediates ethanol-induced alterations in collagen and elastin via a FoxO1-sestrin3-AMPK signaling cascade in myocytes.Direct central nervous system effect of alcohol alters synthesis and degradation of skeletal muscle protein.Autophagy contributes to regulation of the hypoxia response during submergence in Arabidopsis thaliana.Aging accentuates alcohol-induced decrease in protein synthesis in gastrocnemius.Programmed cell death 4 (PDCD4): a novel player in ethanol-mediated suppression of protein translation in primary cortical neurons and developing cerebral cortex.Activation of AMPK/TSC2/PLD by alcohol regulates mTORC1 and mTORC2 assembly in C2C12 myocytes.Pdgfra protects against ethanol-induced craniofacial defects in a zebrafish model of FASD.The Genetics of Fetal Alcohol Spectrum Disorders.Adaptations to excess choline in insulin resistant and Pcyt2 deficient skeletal muscle.FoxO1-AMPK-ULK1 Regulates Ethanol-Induced Autophagy in Muscle by Enhanced ATG14 Association with the BECN1-PIK3C3 Complex.A-674563, a putative AKT1 inhibitor that also suppresses CDK2 activity, inhibits human NSCLC cell growth more effectively than the pan-AKT inhibitor, MK-2206.
P2860
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P2860
Alcohol and PRAS40 knockdown decrease mTOR activity and protein synthesis via AMPK signaling and changes in mTORC1 interaction.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Alcohol and PRAS40 knockdown d ...... changes in mTORC1 interaction.
@en
type
label
Alcohol and PRAS40 knockdown d ...... changes in mTORC1 interaction.
@en
prefLabel
Alcohol and PRAS40 knockdown d ...... changes in mTORC1 interaction.
@en
P2093
P2860
P356
P1476
Alcohol and PRAS40 knockdown d ...... changes in mTORC1 interaction.
@en
P2093
Abid A Kazi
Anne M Pruznak
C Randell Brown
Charles H Lang
Danuta S Huber
Ly Q Hong-Brown
P2860
P304
P356
10.1002/JCB.22496
P577
2010-04-01T00:00:00Z