about
Replication slippage of the thermophilic DNA polymerases B and D from the Euryarchaeota Pyrococcus abyssiThe DNA-damage response in human biology and diseaseDNA slip-outs cause RNA polymerase II arrest in vitro: potential implications for genetic instabilityComparative genomics and molecular dynamics of DNA repeats in eukaryotesEpigenetic principles and mechanisms underlying nervous system functions in health and diseasePalindrome-Mediated Translocations in Humans: A New Mechanistic Model for Gross Chromosomal RearrangementsNew Perspectives on DNA and RNA Triplexes As Effectors of Biological ActivityLinking replication stress with heterochromatin formationAsparaginase treatment side-effects may be due to genes with homopolymeric Asn codons (Review-Hypothesis)Somatic mosaicism in the human genomeRole of DNA polymerase κ in the maintenance of genomic stabilityStructural studies of CNG repeatsInvolvement of long noncoding RNAs in diseases affecting the central nervous systemThe multiple molecular facets of fragile X-associated tremor/ataxia syndromeMechanisms of RNA-induced toxicity in CAG repeat disordersThe balancing act of DNA repeat expansionsRepeat-mediated genetic and epigenetic changes at the FMR1 locus in the Fragile X-related disordersChromosomal translocations and palindromic AT-rich repeatsThe hidden side of unstable DNA repeats: Mutagenesis at a distanceCurrent understanding of the role of microRNAs in spinocerebellar ataxiasMolecular mechanism of resolving trinucleotide repeat hairpin by helicasesSuppression of Somatic Expansion Delays the Onset of Pathophysiology in a Mouse Model of Huntington’s DiseaseContinuous and periodic expansion of CAG repeats in Huntington's disease R6/1 miceStructural dynamics of double-helical RNAs composed of CUG/CUG- and CUG/CGG-repeatsMolecular genetics and genetic testing in myotonic dystrophy type 1.Structural basis for the identification of an i-motif tetraplex core with a parallel-duplex junction as a structural motif in CCG triplet repeatsNew functions of Ctf18-RFC in preserving genome stability outside its role in sister chromatid cohesion.The 26S proteasome drives trinucleotide repeat expansionsRapid unwinding of triplet repeat hairpins by Srs2 helicase of Saccharomyces cerevisiaeMrc1, Tof1 and Csm3 inhibit CAG.CTG repeat instability by at least two mechanisms.Expansion, mosaicism and interruption: mechanisms of the CAG repeat mutation in spinocerebellar ataxia type 1Ups and Downs: Mechanisms of Repeat Instability in the Fragile X-Related DisordersRNA-mediated pathogenic mechanisms in polyglutamine diseases and amyotrophic lateral sclerosisPolyalanine expansion of PHOX2B in congenital central hypoventilation syndrome: rs17884724:A>C is associated with 7-alanine expansionThe G4 genomeA contracted DNA repeat in LHX3 intron 5 is associated with aberrant splicing and pituitary dwarfism in German shepherd dogsInstability of CTG repeats is governed by the position of a DNA base lesion through base excision repairGFP-based fluorescence assay for CAG repeat instability in cultured human cellsCoevolution between simple sequence repeats (SSRs) and virus genome sizeMutSβ promotes trinucleotide repeat expansion by recruiting DNA polymerase β to nascent (CAG)n or (CTG)n hairpins for error-prone DNA synthesis
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Expandable DNA repeats and human disease.
@en
type
label
Expandable DNA repeats and human disease.
@en
prefLabel
Expandable DNA repeats and human disease.
@en
P356
P1433
P1476
Expandable DNA repeats and human disease
@en
P2093
Sergei M Mirkin
P2860
P2888
P304
P356
10.1038/NATURE05977
P407
P577
2007-06-01T00:00:00Z