Tissue transglutaminase contributes to interstitial renal fibrosis by favoring accumulation of fibrillar collagen through TGF-beta activation and cell infiltration. - Wikidata - awgldk - TriplyDB

Tissue transglutaminase contributes to interstitial renal fibrosis by favoring accumulation of fibrillar collagen through TGF-beta activation and cell infiltration.

Tissue transglutaminase contributes to interstitial renal fibrosis by favoring accumulation of fibrillar collagen through TGF-beta activation and cell infiltration.

http://www.wikidata.org/entity/Q36855739

about

New developments in the genetics, pathogenesis, and therapy of IgA nephropathy Transglutaminase 2 has opposing roles in the regulation of cellular functions as well as cell growth and death Restoration of podocyte structure and improvement of chronic renal disease in transgenic mice overexpressing renin.Involvement of IL-13 and tissue transglutaminase in liver granuloma and fibrosis after schistosoma japonicum infection TGF-beta receptor deletion in the renal collecting system exacerbates fibrosis.Novel therapies for coeliac disease LG3 fragment of endorepellin is a possible biomarker of severity in IgA nephropathy.The RenTg mice: a powerful tool to study renin-dependent chronic kidney disease.Epithelial transglutaminase 2 is needed for T cell interleukin-17 production and subsequent pulmonary inflammation and fibrosis in bleomycin-treated mice.Transglutaminase 2 and its role in pulmonary fibrosis.Cordyceps cicadae extracts ameliorate renal malfunction in a remnant kidney model.Transglutaminase 2: a molecular Swiss army knife.Biological Significance of Local TGF-β Activation in Liver Diseases.Transglutaminase is essential for IgA nephropathy development acting through IgA receptors.Cellular and molecular mechanisms of renal fibrosis.Renal interstitial fibrosis: mechanisms and evaluation.Tissue Transglutaminase Mediated Tumor-Stroma Interaction Promotes Pancreatic Cancer Progression Protective effects of genetic inhibition of Discoidin Domain Receptor 1 in experimental renal disease Transglutaminase 2 cross-linking activity is linked to invadopodia formation and cartilage breakdown in arthritis.Airway epithelial cells initiate the allergen response through transglutaminase 2 by inducing IL-33 expression and a subsequent Th2 response.Urinary myeloid IgA Fc alpha receptor (CD89) and transglutaminase-2 as new biomarkers for active IgA nephropathy and henoch-Schönlein purpura nephritis Endostatin and transglutaminase 2 are involved in fibrosis of the aging kidney.Transglutaminase is a Critical Link Between Inflammation and Hypertension.Biomechanical regulation of mesenchymal cell function T-type calcium channel blocker attenuates unilateral ureteral obstruction-induced renal interstitial fibrosis by activating the Nrf2 antioxidant pathway.Recent advances in understanding the roles of transglutaminase 2 in alcoholic steatohepatitis.Potential of transglutaminase 2 as a therapeutic target.Tissue transglutaminase, inflammation, and cancer: how intimate is the relationship?Deposition of IgA in primary IgA nephropathy: it takes at least four to tango.Matrix regulation of idiopathic pulmonary fibrosis: the role of enzymes.A crucial sequence for transglutaminase type 2 extracellular trafficking in renal tubular epithelial cells lies in its N-terminal beta-sandwich domain.Renal allograft fibrosis: biology and therapeutic targets.Transglutaminase 2 in cancer.Syndecan-4 knockout leads to reduced extracellular transglutaminase-2 and protects against tubulointerstitial fibrosis Dihydroisoxazole analogs for labeling and visualization of catalytically active transglutaminase 2.The role of tissue transglutaminase (TG2) in regulating the tumour progression of the mouse colon carcinoma CT26.Atorvastatin has a protective effect in a mouse model of bronchial asthma through regulating tissue transglutaminase and triggering receptor expressed on myeloid cells-1 expression.Transglutaminase 2 in human diseases.Acylideneoxoindoles: a new class of reversible inhibitors of human transglutaminase 2.Tissue transglutaminase inhibition as treatment for diabetic glomerular scarring: it's good to be glueless.

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P2860

Tissue transglutaminase contributes to interstitial renal fibrosis by favoring accumulation of fibrillar collagen through TGF-beta activation and cell infiltration.

http://www.wikidata.org/entity/Q36855739

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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Tissue transglutaminase contri ...... ivation and cell infiltration.

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AJPATH.2008.080025

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The American Journal of Pathology

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Tissue transglutaminase contri ...... tivation and cell infiltration

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Chantal Jouanneau

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Christos Chatziantoniou

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Gerry Melino

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Jean-Claude Dussaule

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Jean-Jacques Boffa

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Nada Boulos

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Nasim Shweke

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Pierre Ronco

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P2860

Latent transforming growth factor-beta binding protein domains involved in activation and transglutaminase-dependent cross-linking of latent transforming growth factor-beta

The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis

Transglutaminase 2: an enigmatic enzyme with diverse functions

Making sense of latent TGFbeta activation

Thrombospondin-1 is a major activator of TGF-beta1 in vivo

Antisense oligonucleotides against thrombospondin-1 inhibit activation of tgf-beta in fibrotic renal disease in the rat in vivo.

Transglutaminase 2 mediates polymer formation of I-kappaBalpha through C-terminal glutamine cluster.

Protein crosslinking in assembly and remodelling of extracellular matrices: the role of transglutaminases.

Transglutaminases: crosslinking enzymes with pleiotropic functions.

Transglutaminase 2-/- mice reveal a phagocytosis-associated crosstalk between macrophages and apoptotic cells.

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