Structure-activity study of brassinin derivatives as indoleamine 2,3-dioxygenase inhibitors. - Wikidata - awgldk - TriplyDB

Structure-activity study of brassinin derivatives as indoleamine 2,3-dioxygenase inhibitors.

Structure-activity study of brassinin derivatives as indoleamine 2,3-dioxygenase inhibitors.

http://www.wikidata.org/entity/Q36856289

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Targeting the indoleamine 2,3-dioxygenase pathway in cancer Trial watch: IDO inhibitors in cancer therapy Severe Acute Respiratory Syndrome Coronavirus Papain-like Novel Protease Inhibitors: Design, Synthesis, Protein−Ligand X-ray Structure and Biological Evaluation Antiproliferative Effect of Indole Phytoalexins Research progress of indoleamine 2,3-dioxygenase inhibitors Nanomedicine and cancer immunotherapy: focus on indoleamine 2,3-dioxygenase inhibitors Nicotinamide adenine dinucleotide metabolism as an attractive target for drug discovery.2-(2,3-Dioxoindolin-1-yl)ethyl 4-(4-nitro-phen-yl)piperazine-1-carbodithio-ate.Inhibitors of indoleamine 2,3-dioxygenase: a review of novel patented lead compounds.Indoleamine 2,3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors.Indoleamine 2,3-dioxygenase in T-cell tolerance and tumoral immune escape.Structure based development of phenylimidazole-derived inhibitors of indoleamine 2,3-dioxygenase.Immunotherapeutic suppression of indoleamine 2,3-dioxygenase and tumor growth with ethyl pyruvate.2-(5-Fluoro-2,3-dioxoindolin-1-yl)ethyl 4-methyl-piperazine-1-carbodithio-ate.Altered tryptophan metabolism as a paradigm for good and bad aspects of immune privilege in chronic inflammatory diseases.Bioisosteric transformations and permutations in the triazolopyrimidine scaffold to identify the minimum pharmacophore required for inhibitory activity against Plasmodium falciparum dihydroorotate dehydrogenase Design, synthesis, and evaluation of pH-dependent hydrolyzable emetine analogues as treatment for prostate cancer.Trial Watch-Small molecules targeting the immunological tumor microenvironment for cancer therapy.The Tumor-Selective Cytotoxic Agent β-Lapachone is a Potent Inhibitor of IDO1 T cell regulatory plasmacytoid dendritic cells expressing indoleamine 2,3 dioxygenase.The phytoalexins from cultivated and wild crucifers: chemistry and biology.Indoleamine 2,3-dioxygenase inhibitors: a patent review (2008 - 2012).Mechanisms of tumor-induced T cell immune suppression and therapeutics to counter those effects.Major developments in the design of inhibitors along the kynurenine pathway.The kynurenine pathway and the brain: Challenges, controversies and promises.ROS-dependent antiproliferative effect of brassinin derivative homobrassinin in human colorectal cancer Caco2 cells.Crinum latifolium leave extracts suppress immune activation cascades in peripheral blood mononuclear cells and proliferation of prostate tumor cells Novel dithiocarbamic acid esters derived from 6-aminomethyl-4-anilinoquinazolines and 6-aminomethyl-4-anilino-3-cyanoquinolines as potent EGFR inhibitors.Synthesis and structure-activity relationships of a novel class of dithiocarbamic acid esters as anticancer agent.Zinc protoporphyrin IX stimulates tumor immunity by disrupting the immunosuppressive enzyme indoleamine 2,3-dioxygenase.Docking Studies and Molecular Dynamic Simulations Reveal Different Features of IDO1 Structure.A novel dithiocarbamate derivative induces cell apoptosis through p53-dependent intrinsic pathway and suppresses the expression of the E6 oncogene of human papillomavirus 18 in HeLa cells.Substrate-protein interaction in human tryptophan dioxygenase: the critical role of H76.Benzyl N-[2-(1H-indol-3-yl)eth-yl]dithio-carbamate.Beyond immunosuppression: reconsidering indoleamine 2,3-dioxygenase as a pathogenic element of chronic inflammation.Studies of the solvatochromic emission properties of N-aroylurea derivatives II: influence of hydrogen-bonding interactions.A key in vivo antitumor mechanism of action of natural product-based brassinins is inhibition of indoleamine 2,3-dioxygenase.Discovery of IDO1 Inhibitors: From Bench to Bedside.Indoleamine 2,3-Dioxygenase and Its Therapeutic Inhibition in Cancer.Inflammatory Reprogramming with IDO1 Inhibitors: Turning Immunologically Unresponsive 'Cold' Tumors 'Hot'.

P2860

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P2860

Structure-activity study of brassinin derivatives as indoleamine 2,3-dioxygenase inhibitors.

http://www.wikidata.org/entity/Q36856289

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2006 nî lūn-bûn

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2006年の論文

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2006年論文

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2006年论文

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2006年论文

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Structure-activity study of br ...... ne 2,3-dioxygenase inhibitors.

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Structure-activity study of br ...... ne 2,3-dioxygenase inhibitors.

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Structure-activity study of br ...... ne 2,3-dioxygenase inhibitors.

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Journal of Medicinal Chemistry

P1476

Structure-activity study of br ...... ine 2,3-dioxygenase inhibitors

@en

P2093

Ashley M Donovan

http://www.w3.org/2001/XMLSchema#string

George C Prendergast

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James DuHadaway

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Paul Gaspari

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Shauna Bennett

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Tinku Banerjee

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William P Malachowski

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P2860

Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

Effects of tryptophan and pH on the kinetics of superoxide radical binding to indoleamine 2,3-dioxygenase studied by pulse radiolysis

1-Methyl-DL-tryptophan, beta-(3-benzofuranyl)-DL-alanine (the oxygen analog of tryptophan), and beta-[3-benzo(b)thienyl]-DL-alanine (the sulfur analog of tryptophan) are competitive inhibitors for indoleamine 2,3-dioxygenase

Phytoalexins from crucifers: synthesis, biosynthesis, and biotransformation.

Heme-Containing Oxygenases.

Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy.

Evidence that reactive oxygen species do not mediate NF-kappaB activation.

Antiproliferative and cancer chemopreventive activity of phytoalexins: focus on indole phytoalexins from crucifers.

IDO and tolerance to tumors.

Tryptophan-derived sulfur-containing phytoalexins--a general overview.

P304

684-692

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10.1021/JM0508888

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2

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49

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Alexander J Muller

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2006-01-01T00:00:00Z

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7352648

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16420054

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2527235

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