about
Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesSpontaneous generation of prion infectivity in fatal familial insomnia knockin miceA heritable switch in carbon source utilization driven by an unusual yeast prionInsights into Mechanisms of Chronic NeurodegenerationPathogenic protein seeding in Alzheimer disease and other neurodegenerative disordersNeurodegenerative diseases: expanding the prion conceptPrion pathogenesis in the absence of NLRP3/ASC inflammasomesSpreading of pathology in neurodegenerative diseases: a focus on human studiesDistinct α-synuclein strains differentially promote tau inclusions in neuronsIn vivo generation of neurotoxic prion protein: role for hsp70 in accumulation of misfolded isoformsAnalysis of Conformational Stability of Abnormal Prion Protein Aggregates across the Spectrum of Creutzfeldt-Jakob Disease PrionsReview: A review on classical and atypical scrapie in caprine: Prion protein gene polymorphisms and their role in the disease.Mammalian prions: tolerance to sequence changes-how far?Human prion diseases in the Netherlands (1998-2009): clinical, genetic and molecular aspects.Heat shock factor 1 regulates lifespan as distinct from disease onset in prion disease.High-speed atomic force microscopy reveals structural dynamics of amyloid β1-42 aggregates.Brain transcriptional stability upon prion protein-encoding gene invalidation in zygotic or adult mouseFunctional depletion of mahogunin by cytosolically exposed prion protein contributes to neurodegenerationAccumulation of citrullinated proteins by up-regulated peptidylarginine deiminase 2 in brains of scrapie-infected mice: a possible role in pathogenesisThe comprehensive native interactome of a fully functional tagged prion proteinPathologic prion protein infects cells by lipid-raft dependent macropinocytosisUnexpected tolerance of alpha-cleavage of the prion protein to sequence variationsContext dependent neuroprotective properties of prion protein (PrP).Amyloid-like aggregates of the yeast prion protein ure2 enter vertebrate cells by specific endocytotic pathways and induce apoptosis.Intrastriatal injection of α-synuclein can lead to widespread synucleinopathy independent of neuroanatomic connectivity.Molecular polymorphism of Abeta in Alzheimer's disease.Types and Strains: Their Essential Role in Understanding Protein Aggregation in Neurodegenerative Diseases.Modeling routes of chronic wasting disease transmission: environmental prion persistence promotes deer population decline and extinction.Molecular structure of amyloid fibrils controls the relationship between fibrillar size and toxicity.Transcriptomic analysis brings new insight into the biological role of the prion protein during mouse embryogenesisMetabolism of minor isoforms of prion proteins: Cytosolic prion protein and transmembrane prion proteinAgent strain variation in human prion disease: insights from a molecular and pathological review of the National Institutes of Health series of experimentally transmitted disease.Distinct stability states of disease-associated human prion protein identified by conformation-dependent immunoassaySequence-dependent prion protein misfolding and neurotoxicity.Prion protein and Shadoo are involved in overlapping embryonic pathways and trophoblastic developmentUnfolded protein response-induced ERdj3 secretion links ER stress to extracellular proteostasis.Novel therapeutic strategy for neurodegeneration by blocking Aβ seeding mediated aggregation in models of Alzheimer's disease.Tracking protein aggregate interactions.Mammalian prions: tracking the infectious entitiesInteraction of prion protein with acetylcholinesterase: potential pathobiological implications in prion diseases.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Insights into prion strains and neurotoxicity.
@en
type
label
Insights into prion strains and neurotoxicity.
@en
prefLabel
Insights into prion strains and neurotoxicity.
@en
P2860
P356
P1476
Insights into prion strains and neurotoxicity.
@en
P2093
Magdalini Polymenidou
P2860
P2888
P304
P356
10.1038/NRM2204
P577
2007-07-01T00:00:00Z