T cell-specific notch inhibition blocks graft-versus-host disease by inducing a hyporesponsive program in alloreactive CD4+ and CD8+ T cells.
about
Rescue of notch-1 signaling in antigen-specific CD8+ T cells overcomes tumor-induced T-cell suppression and enhances immunotherapy in cancerNotch signaling at later stages of NK cell development enhances KIR expression and functional maturationPhase 2 study of RO4929097, a gamma-secretase inhibitor, in metastatic melanoma: SWOG 0933.Transient blockade of delta-like Notch ligands prevents allograft rejection mediated by cellular and humoral mechanisms in a mouse model of heart transplantation.Control of peripheral tolerance by regulatory T cell-intrinsic Notch signaling.Notch signaling regulates T cell accumulation and function in the central nervous system during experimental autoimmune encephalomyelitis.Notch signaling in hematopoietic cell transplantation and T cell alloimmunity.Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands.Cellular and molecular mechanisms in graft-versus-host disease.Tregs: hype or hope for allogeneic hematopoietic stem cell transplantation?Targeting the Notch Pathway to Prevent Rejection.Notch Signaling and Alloreactivity.Notch regulates Th17 differentiation and controls trafficking of IL-17 and metabolic regulators within Th17 cells in a context-dependent manner.T Cell-Restricted Notch Signaling Contributes to Pulmonary Th1 and Th2 Immunity during Cryptococcus neoformans Infection.Notch Ligand Delta-like 4 Promotes Regulatory T Cell Identity in Pulmonary Viral Infection.Bone marrow transplant-induced alterations in Notch signaling promote pathologic Th17 responses to γ-herpesvirus infection.Regulation of CD8+ T Cells and Antitumor Immunity by Notch Signaling.T cells take directions from supporting cast in graft-versus-host disease.Notch pathway plays a novel and critical role in regulating responses of T and antigen-presenting cells in aGVHD.The NOTCH1/CD39 axis: a Treg trip-switch for GvHD.Advance in Targeted Immunotherapy for Graft-Versus-Host Disease.T-Cell Manipulation Strategies to Prevent Graft-Versus-Host Disease in Haploidentical Stem Cell Transplantation.Notch Signaling and Immune Regulation in Alloimmunity.NOTCH and Graft-Versus-Host Disease
P2860
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P2860
T cell-specific notch inhibition blocks graft-versus-host disease by inducing a hyporesponsive program in alloreactive CD4+ and CD8+ T cells.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
T cell-specific notch inhibiti ...... eactive CD4+ and CD8+ T cells.
@en
type
label
T cell-specific notch inhibiti ...... eactive CD4+ and CD8+ T cells.
@en
prefLabel
T cell-specific notch inhibiti ...... eactive CD4+ and CD8+ T cells.
@en
P2093
P2860
P356
P1476
T cell-specific notch inhibiti ...... eactive CD4+ and CD8+ T cells.
@en
P2093
Ann Friedman
Ashley R Sandy
Gloria T Shan
Ivan Maillard
Ivy T Tran
Jooho Chung
Pavan Reddy
Philip D King
Timothy S Blackwell
Tomomi Toubai
P2860
P304
P356
10.4049/JIMMUNOL.1203452
P407
P577
2013-05-01T00:00:00Z