Analysis of 3-phosphoinositide-dependent kinase-1 signaling and function in ES cells.
about
Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2Genetic and Pharmacological Inhibition of PDK1 in Cancer Cells: CHARACTERIZATION OF A SELECTIVE ALLOSTERIC KINASE INHIBITORDevelopment of high-throughput TR-FRET and AlphaScreen assays for identification of potent inhibitors of PDK1.Dax1 up-regulates Oct4 expression in mouse embryonic stem cells via LRH-1 and SRA.3-Phosphoinositide-dependent kinase 1 potentiates upstream lesions on the phosphatidylinositol 3-kinase pathway in breast carcinoma.The PDK1 master kinase is over-expressed in acute myeloid leukemia and promotes PKC-mediated survival of leukemic blasts.Discovery and structure of a new inhibitor scaffold of the autophagy initiating kinase ULK1.Synthesis and evaluation of indazole based analog sensitive Akt inhibitorsCharacterization of GSK2334470, a novel and highly specific inhibitor of PDK1.Evaluation of human microtubule affinity-regulating kinase 4 inhibitors: fluorescence binding studies, enzyme, and cell assays.PDK1 selectively phosphorylates Thr(308) on Akt and contributes to human platelet functional responses.For a PDK1 inhibitor, the substrate matters.
P2860
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P2860
Analysis of 3-phosphoinositide-dependent kinase-1 signaling and function in ES cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Analysis of 3-phosphoinositide-dependent kinase-1 signaling and function in ES cells.
@en
type
label
Analysis of 3-phosphoinositide-dependent kinase-1 signaling and function in ES cells.
@en
prefLabel
Analysis of 3-phosphoinositide-dependent kinase-1 signaling and function in ES cells.
@en
P2093
P2860
P1476
Analysis of 3-phosphoinositide-dependent kinase-1 signaling and function in ES cells.
@en
P2093
Chao Zhang
David Stokoe
Dorothea Fiedler
Kevan Shokat
Tanja Tamgüney
P2860
P304
P356
10.1016/J.YEXCR.2008.04.006
P407
P577
2008-04-23T00:00:00Z