Analysis of 3-phosphoinositide-dependent kinase-1 signaling and function in ES cells. - Wikidata - awgldk - TriplyDB

Analysis of 3-phosphoinositide-dependent kinase-1 signaling and function in ES cells.

Analysis of 3-phosphoinositide-dependent kinase-1 signaling and function in ES cells.

http://www.wikidata.org/entity/Q36865347

about

Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2 Genetic and Pharmacological Inhibition of PDK1 in Cancer Cells: CHARACTERIZATION OF A SELECTIVE ALLOSTERIC KINASE INHIBITOR Development of high-throughput TR-FRET and AlphaScreen assays for identification of potent inhibitors of PDK1.Dax1 up-regulates Oct4 expression in mouse embryonic stem cells via LRH-1 and SRA.3-Phosphoinositide-dependent kinase 1 potentiates upstream lesions on the phosphatidylinositol 3-kinase pathway in breast carcinoma.The PDK1 master kinase is over-expressed in acute myeloid leukemia and promotes PKC-mediated survival of leukemic blasts.Discovery and structure of a new inhibitor scaffold of the autophagy initiating kinase ULK1.Synthesis and evaluation of indazole based analog sensitive Akt inhibitors Characterization of GSK2334470, a novel and highly specific inhibitor of PDK1.Evaluation of human microtubule affinity-regulating kinase 4 inhibitors: fluorescence binding studies, enzyme, and cell assays.PDK1 selectively phosphorylates Thr(308) on Akt and contributes to human platelet functional responses.For a PDK1 inhibitor, the substrate matters.

P2860

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P2860

Analysis of 3-phosphoinositide-dependent kinase-1 signaling and function in ES cells.

http://www.wikidata.org/entity/Q36865347

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

2008年论文

@zh

2008年论文

@zh-cn

name

Analysis of 3-phosphoinositide-dependent kinase-1 signaling and function in ES cells.

@en

type

label

Analysis of 3-phosphoinositide-dependent kinase-1 signaling and function in ES cells.

@en

prefLabel

Analysis of 3-phosphoinositide-dependent kinase-1 signaling and function in ES cells.

@en

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P356

J.YEXCR.2008.04.006

P1433

Experimental Cell Research

P1476

Analysis of 3-phosphoinositide-dependent kinase-1 signaling and function in ES cells.

@en

P2093

Chao Zhang

http://www.w3.org/2001/XMLSchema#string

David Stokoe

http://www.w3.org/2001/XMLSchema#string

Dorothea Fiedler

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Kevan Shokat

http://www.w3.org/2001/XMLSchema#string

Tanja Tamgüney

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P2860

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

PDK1, the master regulator of AGC kinase signal transduction

Phosphorylation and activation of p70s6k by PDK1

Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2

Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo

Essential role of PDK1 in regulating cell size and development in mice

Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase.

S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway

The selectivity of protein kinase inhibitors: a further update

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

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2299-2312

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scholarly article

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10.1016/J.YEXCR.2008.04.006

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11-12

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314

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2008-04-23T00:00:00Z

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5337158

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18514190

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2531073

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