Role of protein-protein interactions in the function of replication protein A (RPA): RPA modulates the activity of DNA polymerase alpha by multiple mechanisms.
about
Human single-stranded DNA binding proteins are essential for maintaining genomic stabilityRBT1, a novel transcriptional co-activator, binds the second subunit of replication protein ACellular functions of human RPA1. Multiple roles of domains in replication, repair, and checkpointsAn alternative form of replication protein a prevents viral replication in vitroTimed interactions between viral and cellular replication factors during the initiation of SV40 in vitro DNA replicationDifferent activities of the largest subunit of replication protein A cooperate during SV40 DNA replicationInteraction of human rad51 recombination protein with single-stranded DNA binding protein, RPANMR chemical shift and relaxation measurements provide evidence for the coupled folding and binding of the p53 transactivation domainSolution structure of the DNA-binding domain of RPA from Saccharomyces cerevisiae and its interaction with single-stranded DNA and SV40 T antigenStructure of the major single-stranded DNA-binding domain of replication protein A suggests a dynamic mechanism for DNA binding.Structure and conformational change of a replication protein A heterotrimer bound to ssDNADiscovery of Protein–Protein Interaction Inhibitors of Replication Protein AThe interaction of p53 with replication protein A mediates suppression of homologous recombinationIn vitro analysis of the zinc-finger motif in human replication protein ADNA-binding polarity of human replication protein A positions nucleases in nucleotide excision repairA dynamic model for replication protein A (RPA) function in DNA processing pathwaysPlasmodium falciparum possesses a cell cycle-regulated short type replication protein A large subunit encoded by an unusual transcriptSaccharomyces cerevisiae replication protein A binds to single-stranded DNA in multiple salt-dependent modesInteractions of the papovavirus DNA replication initiator proteins, bovine papillomavirus type 1 E1 and simian virus 40 large T antigen, with human replication protein ADNA replication but not nucleotide excision repair is required for UVC-induced replication protein A phosphorylation in mammalian cellsStopped-flow kinetic analysis of replication protein A-binding DNA: damage recognition and affinity for single-stranded DNA reveal differential contributions of k(on) and k(off) rate constants.UV-induced hyperphosphorylation of replication protein a depends on DNA replication and expression of ATM protein.Replication protein A in Pyrococcus furiosus is involved in homologous DNA recombination.Functional analysis of the four DNA binding domains of replication protein A. The role of RPA2 in ssDNA binding.Bimodal interaction between replication-protein A and Dna2 is critical for Dna2 function both in vivo and in vitro.Mutational analysis of simian virus 40 T-antigen primosome activities in viral DNA replication.Role of the p68 subunit of human DNA polymerase alpha-primase in simian virus 40 DNA replicationDNA damage induced hyperphosphorylation of replication protein A. 2. Characterization of DNA binding activity, protein interactions, and activity in DNA replication and repair.Chemical shift changes provide evidence for overlapping single-stranded DNA- and XPA-binding sites on the 70 kDa subunit of human replication protein AXeroderma pigmentosum complementation group A protein (XPA) modulates RPA-DNA interactions via enhanced complex stability and inhibition of strand separation activity.Parvovirus initiator protein NS1 and RPA coordinate replication fork progression in a reconstituted DNA replication system.Protein-protein interactions of the primase subunits p58 and p48 with simian virus 40 T antigen are required for efficient primer synthesis in a cell-free system.The replication protein A binding site in simian virus 40 (SV40) T antigen and its role in the initial steps of SV40 DNA replication.The middle subunit of replication protein A contacts growing RNA-DNA primers in replicating simian virus 40 chromosomesFunctional analysis of human replication protein A in nucleotide excision repair.RFWD3-Dependent Ubiquitination of RPA Regulates Repair at Stalled Replication Forks.Assembly of the replication initiation complex on SV40 origin DNA.Human replication protein A (RPA) binds a primer-template junction in the absence of its major ssDNA-binding domains.Coordinated regulation of replication protein A activities by its subunits p14 and p32.DNA damage induced hyperphosphorylation of replication protein A. 1. Identification of novel sites of phosphorylation in response to DNA damage.
P2860
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P2860
Role of protein-protein interactions in the function of replication protein A (RPA): RPA modulates the activity of DNA polymerase alpha by multiple mechanisms.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Role of protein-protein intera ...... alpha by multiple mechanisms.
@en
type
label
Role of protein-protein intera ...... alpha by multiple mechanisms.
@en
prefLabel
Role of protein-protein intera ...... alpha by multiple mechanisms.
@en
P2093
P356
P1433
P1476
Role of protein-protein intera ...... alpha by multiple mechanisms.
@en
P2093
P304
P356
10.1021/BI970473R
P407
P577
1997-07-01T00:00:00Z