Latent herpes simplex virus type 1 transcription in human trigeminal ganglia
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17-beta estradiol promotion of herpes simplex virus type 1 reactivation is estrogen receptor dependentIdentification of a novel latency-specific splice donor signal within the herpes simplex virus type 1 2.0-kilobase latency-associated transcript (LAT): translation inhibition of LAT open reading frames by the intron within the 2.0-kilobase LAT.Herpes simplex virus type 1 latency-associated transcripts are evidently not essential for latent infection.Latency-associated transcripts in corneas and ganglia of HSV-1 infected rabbitsEnhancer and long-term expression functions of herpes simplex virus type 1 latency-associated promoter are both located in the same regionHerpes simplex virus type 1 latency-associated transcription unit promotes anatomical site-dependent establishment and reactivation from latency.Structural and kinetic analyses of herpes simplex virus type 1 latency-associated transcripts in human trigeminal ganglia and in cell cultureChronic progressive deficits in neuron size, density and number in the trigeminal ganglia of mice latently infected with herpes simplex virus.Quantification of transcripts from the ICP4 and thymidine kinase genes in mouse ganglia latently infected with herpes simplex virusAnalysis of the promoter and cis-acting elements regulating expression of herpes simplex virus type 2 latency-associated transcriptsThe region of the herpes simplex virus type 1 LAT gene that is colinear with the ICP34.5 gene is not involved in spontaneous reactivation.The spontaneous reactivation function of the herpes simplex virus type 1 LAT gene resides completely within the first 1.5 kilobases of the 8.3-kilobase primary transcript.A 371-nucleotide region between the herpes simplex virus type 1 (HSV-1) LAT promoter and the 2-kilobase LAT is not essential for efficient spontaneous reactivation of latent HSV-1The abundant latency-associated transcripts of herpes simplex virus type 1 are bound to polyribosomes in cultured neuronal cells and during latent infection in mouse trigeminal ganglia.Latent herpes simplex virus type 1 gene expression in ganglia innervating the human gastrointestinal tract.Selection of a nonconsensus branch point is influenced by an RNA stem-loop structure and is important to confer stability to the herpes simplex virus 2-kilobase latency-associated transcriptMutations in the 5' end of the herpes simplex virus type 2 latency-associated transcript (LAT) promoter affect LAT expression in vivo but not the rate of spontaneous reactivation of genital herpesExpression of a herpes simplex virus 1 open reading frame antisense to the gamma(1)34.5 gene and transcribed by an RNA 3' coterminal with the unspliced latency-associated transcript.The latency-associated transcript gene of herpes simplex virus type 1 (HSV-1) is required for efficient in vivo spontaneous reactivation of HSV-1 from latencyHerpes simplex virus type 1 latency-associated transcript (LAT) promoter deletion mutants can express a 2-kilobase transcript mapping to the LAT region.Relationship between polyadenylated and nonpolyadenylated herpes simplex virus type 1 latency-associated transcripts.Herpes simplex viruses with mutations in the gene encoding ICP0 are defective in gene expression.Localization of cis-acting sequence requirements in the promoter of the latency-associated transcript of herpes simplex virus type 1 required for cell-type-specific activity.During latency, herpes simplex virus type 1 DNA is associated with nucleosomes in a chromatin structureCharacterization of herpes simplex virus type 2 transcription during latent infection of mouse trigeminal ganglia.The nucleotide sequence, 5' end, promoter domain, and kinetics of expression of the gene encoding the herpes simplex virus type 2 latency-associated transcript.A herpes simplex virus type 1 mutant containing a nontransinducing Vmw65 protein establishes latent infection in vivo in the absence of viral replication and reactivates efficiently from explanted trigeminal ganglia.In vivo and in vitro reactivation impairment of a herpes simplex virus type 1 latency-associated transcript variant in a rabbit eye model.Herpes simplex virus type 1 latency-associated transcription plays no role in establishment or maintenance of a latent infection in murine sensory neurons.Expression of herpes simplex virus type 1 (HSV-1) latency-associated transcripts and transcripts affected by the deletion in avirulent mutant HFEM: evidence for a new class of HSV-1 genes.Human herpesviruses: a consideration of the latent state.Transgenic mouse with the herpes simplex virus type 1 latency-associated gene: expression and function of the transgeneCorneal latency and transmission of herpes simplex virus-1.Herpes Simplex Virus-1 Encephalitis in Adults: Pathophysiology, Diagnosis, and Management.Herpes simplex virus type 1 latency-associated transcripts suppress viral replication and reduce immediate-early gene mRNA levels in a neuronal cell lineRegulation and cell-type-specific activity of a promoter located upstream of the latency-associated transcript of herpes simplex virus type 1.
P2860
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P2860
Latent herpes simplex virus type 1 transcription in human trigeminal ganglia
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Latent herpes simplex virus type 1 transcription in human trigeminal ganglia
@en
type
label
Latent herpes simplex virus type 1 transcription in human trigeminal ganglia
@en
prefLabel
Latent herpes simplex virus type 1 transcription in human trigeminal ganglia
@en
P2093
P2860
P1433
P1476
Latent herpes simplex virus type 1 transcription in human trigeminal ganglia
@en
P2093
P2860
P304
P407
P577
1988-09-01T00:00:00Z