Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus - Wikidata - awgldk - TriplyDB

Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus

Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus

http://www.wikidata.org/entity/Q36872701

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State of Knowledge and Data Gaps of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in Humans Emergence of the Middle East respiratory syndrome coronavirus Network-based analysis of comorbidities risk during an infection: SARS and HIV case studies The host immune response in respiratory virus infection: balancing virus clearance and immunopathology.Middle East Respiratory Syndrome Coronavirus (MERS-CoV): a perpetual challenge Crystal Structure of the Receptor-Binding Domain from Newly Emerged Middle East Respiratory Syndrome Coronavirus Coronaviruses and the human airway: a universal system for virus-host interaction studies From SARS to MERS: evidence and speculation.A review of treatment modalities for Middle East Respiratory Syndrome.Middle East Respiratory Syndrome.Transcriptomic characterization of the novel avian-origin influenza A (H7N9) virus: specific host response and responses intermediate between avian (H5N1 and H7N7) and human (H3N2) viruses and implications for treatment options A mouse model for Betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variant Pathogenic influenza viruses and coronaviruses utilize similar and contrasting approaches to control interferon-stimulated gene responses.Influenza virus A/Anhui/1/2013 (H7N9) replicates efficiently in the upper and lower respiratory tracts of cynomolgus macaques.A comprehensive collection of systems biology data characterizing the host response to viral infection.Drug repurposing: a better approach for infectious disease drug discovery?Systems approaches to Coronavirus pathogenesis.The emergence of the Middle East respiratory syndrome coronavirus Antiviral potential of ERK/MAPK and PI3K/AKT/mTOR signaling modulation for Middle East respiratory syndrome coronavirus infection as identified by temporal kinome analysis Middle East respiratory syndrome coronavirus: another zoonotic betacoronavirus causing SARS-like disease Coronavirus non-structural protein 16: evasion, attenuation, and possible treatments.Distinct immune response in two MERS-CoV-infected patients: can we go from bench to bedside?Cytokine systems approach demonstrates differences in innate and pro-inflammatory host responses between genetically distinct MERS-CoV isolates.Association between the Severity of Influenza A(H7N9) Virus Infections and Length of the Incubation Period.A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates.The effect of inhibition of PP1 and TNFα signaling on pathogenesis of SARS coronavirus The NF-κB-dependent and -independent transcriptome and chromatin landscapes of human coronavirus 229E-infected cells.Lung epithelial cells have virus-specific and shared gene expression responses to infection by diverse respiratory viruses.Dipeptidyl Peptidase 4 Distribution in the Human Respiratory Tract: Implications for the Middle East Respiratory Syndrome.Middle East respiratory syndrome coronavirus shows poor replication but significant induction of antiviral responses in human monocyte-derived macrophages and dendritic cells.Severe acute respiratory syndrome coronavirus nonstructural proteins 3, 4, and 6 induce double-membrane vesicles Bugs in the system.Bilateral entry and release of Middle East respiratory syndrome coronavirus induces profound apoptosis of human bronchial epithelial cells.Aptamer-based therapeutics: new approaches to combat human viral diseases Cell-based antiviral screening against coronaviruses: developing virus-specific and broad-spectrum inhibitors Evaluation of serologic and antigenic relationships between middle eastern respiratory syndrome coronavirus and other coronaviruses to develop vaccine platforms for the rapid response to emerging coronaviruses.Attenuation and restoration of severe acute respiratory syndrome coronavirus mutant lacking 2'-o-methyltransferase activity.Middle East respiratory syndrome coronavirus (MERS-CoV): evidence and speculations.Systems biology unravels interferon responses to respiratory virus infections.Coronavirus entry and release in polarized epithelial cells: a review.

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Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus

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Cell host response to infectio ...... ferences with SARS coronavirus

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Cell host response to infectio ...... ferences with SARS coronavirus

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Boyd L Yount

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Lisa E Gralinski

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Pavel Sova

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Rachel L Graham

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Sudhakar Agnihothram

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Victoria S Carter

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P2860

SARS: systematic review of treatment effects

Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

Human coronavirus EMC does not require the SARS-coronavirus receptor and maintains broad replicative capability in mammalian cell lines

Efficient replication of the novel human betacoronavirus EMC on primary human epithelium highlights its zoonotic potential

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Activation of the PI3K/Akt Pathway Early during Vaccinia and Cowpox Virus Infections Is Required for both Host Survival and Viral Replication

Design and synthesis of inhaled p38 inhibitors for the treatment of chronic obstructive pulmonary disease

Primer3 on the WWW for general users and for biologist programmers

Gene expression signature-based screening identifies new broadly effective influenza a antivirals

The Connectivity Map: a new tool for biomedical research

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Vineet D. Menachery

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severe acute respiratory syndrome-related coronavirus

severe acute respiratory syndrome coronavirus

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