PARP1 is required for chromosomal translocations. - Wikidata - awgldk - TriplyDB

PARP1 is required for chromosomal translocations.

PARP1 is required for chromosomal translocations.

http://www.wikidata.org/entity/Q36873293

about

Cross talk of tyrosine kinases with the DNA damage signaling pathways DNA Damage and Pulmonary Hypertension Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?Radiation-associated neoplasia: clinical, pathological and genomic correlates.PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA.Efficient Recreation of t(11;22) EWSR1-FLI1+ in Human Stem Cells Using CRISPR/Cas9.Requirement for Parp-1 and DNA ligases 1 or 3 but not of Xrcc1 in chromosomal translocation formation by backup end joining.53BP1 promotes microhomology-mediated end-joining in G1-phase cells.BRCA1 Mutation: A Predictive Marker for Radiation Therapy?Normal ABL1 is a tumor suppressor and therapeutic target in human and mouse leukemias expressing oncogenic ABL1 kinases.Characterization of in vitro radiosensitization in mammalian cells using biomathematical modelling: implications for hypofractionated radiotherapy with a combined modality approach Endonuclease EEPD1 Is a Gatekeeper for Repair of Stressed Replication Forks Topoisomerase II and leukemia.The bone marrow niche, stem cells, and leukemia: impact of drugs, chemicals, and the environment.Mechanisms of oncogenic chromosomal translocations.DNA damage accumulation and repair defects in acute myeloid leukemia: implications for pathogenesis, disease progression, and chemotherapy resistance.Topoisomerase-mediated chromosomal break repair: an emerging player in many games.Synthetic lethality in malignant pleural mesothelioma with PARP1 inhibition.Identifying high-risk adult AML patients: epigenetic and genetic risk factors and their implications for therapy.Etoposide quinone is a covalent poison of human topoisomerase IIβ.PREVENTING THE CHROMOSOMAL TRANSLOCATIONS THAT CAUSE CANCER Common and unique genetic interactions of the poly(ADP-ribose) polymerases PARP1 and PARP2 with DNA double-strand break repair pathways.Genomic instability is a principle pathologic feature of FLT3 ITD kinase activity in acute myeloid leukemia leading to clonal evolution and disease progression.Alternative NHEJ pathway proteins as components of MYCN oncogenic activity in human neural crest stem cell differentiation: implications for neuroblastoma initiation.The Association between PARP1 and LIG3 Expression Levels and Chromosomal Translocations in Acute Myeloid Leukemia Patients.PARP1 is required for preserving telomeric integrity but is dispensable for A-NHEJ

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P2860

PARP1 is required for chromosomal translocations.

http://www.wikidata.org/entity/Q36873293

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

@zh

2013年论文

@zh-cn

name

PARP1 is required for chromosomal translocations.

@en

type

label

PARP1 is required for chromosomal translocations.

@en

prefLabel

PARP1 is required for chromosomal translocations.

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BLOOD-2012-10-460527

P1433

P1476

PARP1 is required for chromosomal translocations

@en

P2093

Daohong Zhou

http://www.w3.org/2001/XMLSchema#string

David M Weinstock

http://www.w3.org/2001/XMLSchema#string

Elizabeth A Williamson

http://www.w3.org/2001/XMLSchema#string

Jac A Nickoloff

http://www.w3.org/2001/XMLSchema#string

Justin Wray

http://www.w3.org/2001/XMLSchema#string

Lijian Shao

http://www.w3.org/2001/XMLSchema#string

Martin Hauer-Jensen

http://www.w3.org/2001/XMLSchema#string

Robert Hromas

http://www.w3.org/2001/XMLSchema#string

Rupak Pathak

http://www.w3.org/2001/XMLSchema#string

Sudha B Singh

http://www.w3.org/2001/XMLSchema#string

P2860

DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation

The transposase domain protein Metnase/SETMAR suppresses chromosomal translocations

Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1)

Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers.

The taming of a transposon: V(D)J recombination and the immune system

PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways

Small-molecule PARP modulators--current status and future therapeutic potential.

Synthetic lethality: exploiting the addiction of cancer to DNA repair.

Formation of NHEJ-derived reciprocal chromosomal translocations does not require Ku70.

Genetics of myeloid leukemias.

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4359-4365

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scholarly article

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10.1182/BLOOD-2012-10-460527

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21

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Christopher R. Cogle

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2013-04-08T00:00:00Z

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236139939

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23568489

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3663429

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