The orphan G protein-coupled receptor, Gpr161, encodes the vacuolated lens locus and controls neurulation and lens development. - Wikidata - awgldk - TriplyDB

The orphan G protein-coupled receptor, Gpr161, encodes the vacuolated lens locus and controls neurulation and lens development.

The orphan G protein-coupled receptor, Gpr161, encodes the vacuolated lens locus and controls neurulation and lens development.

http://www.wikidata.org/entity/Q36883085

about

Ins and outs of GPCR signaling in primary cilia Primary cilium and sonic hedgehog signaling during neural tube patterning: role of GPCRs and second messengers Strain-specific modifier genes of Cecr2-associated exencephaly in mice: genetic analysis and identification of differentially expressed candidate genes The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear.G protein coupled receptors in embryonic stem cells: a role for Gs-alpha signaling.Cat-Map: putting cataract on the map Clinical and experimental advances in congenital and paediatric cataracts.Whole-exome sequencing identifies homozygous GPR161 mutation in a family with pituitary stalk interruption syndrome.Focusing forward genetics: a tripartite ENU screen for neurodevelopmental mutations in the mouse Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans.Hunting for the function of orphan GPCRs - beyond the search for the endogenous ligand.Mechanisms of tissue fusion during development.Congenital Cataract in Gpr161vl/vl Mice Is Modified by Proximal Chromosome 15.The orphan G protein-coupled receptor 161 is required for left-right patterning Smoothened determines β-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium Gpr161 anchoring of PKA consolidates GPCR and cAMP signaling INPP5E regulates phosphoinositide-dependent cilia transition zone function.G-protein-coupled receptor GPR161 is overexpressed in breast cancer and is a promoter of cell proliferation and invasion.Toward the next step in G protein-coupled receptor research: a knowledge-driven analysis for the next potential targets in drug discovery.Genetic modifiers as relevant biological variables of eye disorders.Identification and developmental expression of leucine-rich repeat-containing G protein-coupled receptor 6 (lgr6) in the medaka fish, Oryzias latipes.The Opdc missense mutation of Pax2 has a milder than loss-of-function phenotype.The G-protein-coupled receptor, GPR84, is important for eye development in Xenopus laevis.Mutation update of transcription factor genes FOXE3, HSF4, MAF, and PITX3 causing cataracts and other developmental ocular defects.G-protein-coupled receptors and localized signaling in the primary cilium during ventral neural tube patterning.Integrated analysis identified an intestinal-like and a diffuse-like gene sets that predict gastric cancer outcome.G-protein-coupled receptor signaling and neural tube closure defects.Quantitative trait loci affecting phenotypic variation in the vacuolated lens mouse mutant, a multigenic mouse model of neural tube defects

P2860

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P2860

The orphan G protein-coupled receptor, Gpr161, encodes the vacuolated lens locus and controls neurulation and lens development.

http://www.wikidata.org/entity/Q36883085

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

The orphan G protein-coupled r ...... rulation and lens development.

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type

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The orphan G protein-coupled r ...... rulation and lens development.

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The orphan G protein-coupled r ...... rulation and lens development.

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Proceedings of the National Academy of Sciences of the United States of America

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The orphan G protein-coupled r ...... rulation and lens development.

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Beverly Paigen

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Gloria Lazar

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James H Millonig

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Jamie Joseph

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Jarod Rollins

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Jason Wink

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Jigar Desai

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Paul G Matteson

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Ron Korstanje

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Rym Benayed

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P2860

A forkhead gene, FoxE3, is essential for lens epithelial proliferation and closure of the lens vesicle

Foxe3 haploinsufficiency in mice: a model for Peters' anomaly

Homozygous nonsense mutation in the FOXE3 gene as a cause of congenital primary aphakia in humans

Causes of childhood blindness: results from schools for the blind in south eastern Nigeria

Agonist-induced endocytosis of lysophosphatidic acid-coupled LPA1/EDG-2 receptors via a dynamin2- and Rab5-dependent pathway

Forkhead Foxe3 maps to the dysgenetic lens locus and is critical in lens development and differentiation

Knobloch syndrome involving midline scalp defect of the frontal region.

Mouse models for neural tube closure defects.

Mutations in the human forkhead transcription factor FOXE3 associated with anterior segment ocular dysgenesis and cataracts.

Neural fold formation at newly created boundaries between neural plate and epidermis in the axolotl.

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2088-2093

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105

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G protein-coupled receptor

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