Hepatocyte-targeted RNAi therapeutics for the treatment of chronic hepatitis B virus infection - Wikidata - awgldk - TriplyDB

Hepatocyte-targeted RNAi therapeutics for the treatment of chronic hepatitis B virus infection

Hepatocyte-targeted RNAi therapeutics for the treatment of chronic hepatitis B virus infection

http://www.wikidata.org/entity/Q36883851

about

Lipid nanoparticles for targeted siRNA delivery - going from bench to bedside DNA Nanotechnology for Cancer Therapy Prevention and Treatment of Recurrent Hepatitis B after Liver Transplantation Therapeutic Oligonucleotides Targeting Liver Disease: TTR Amyloidosis Therapeutic Strategies and New Intervention Points in Chronic Hepatitis Delta Virus Infection Progress and Prospects of Anti-HBV Gene Therapy Development Hepatitis delta: epidemiology, diagnosis and management 36 years after discovery Lipid nanoparticles as carriers for RNAi against viral infections: current status and future perspectives Management of chronic hepatitis B infection: current treatment guidelines, challenges, and new developments Hepatitis B: future curative strategies Inhibitor-Based Therapeutics for Treatment of Viral Hepatitis Knocking down disease: a progress report on siRNA therapeutics Current and future antiviral drug therapies of hepatitis B chronic infection Asian-Pacific clinical practice guidelines on the management of hepatitis B: a 2015 update.Phosphorylation-specific status of RNAi triggers in pharmacokinetic and biodistribution analyses Mechanisms of nanoparticle-mediated siRNA transfection by melittin-derived peptides.Enhanced antiviral and antifibrotic effects of short hairpin RNAs targeting HBV and TGF-β in HBV-persistent mice.RNAi therapies: drugging the undruggable.Recent In Vivo Evidences of Particle-Based Delivery of Small-Interfering RNA (siRNA) into Solid Tumors Prospects for inhibiting the post-transcriptional regulation of gene expression in hepatitis B virus.Hepatitis B virus: new therapeutic perspectives.Bioenergetics and gene silencing approaches for unraveling nucleotide recognition by the human EIF2C2/Ago2 PAZ domain.Antiviral therapies and prospects for a cure of chronic hepatitis B.Unveiling the roles of HBV polymerase for new antiviral strategies A role for peptides in overcoming endosomal entrapment in siRNA delivery - A focus on melittin Systemic Administration of siRNA via cRGD-containing Peptide.Combinatorial RNA Interference Therapy Prevents Selection of Pre-existing HBV Variants in Human Liver Chimeric Mice.Scalable preparation of poly(ethylene glycol)-grafted siRNA-loaded lipid nanoparticles using a commercially available fluidic device and tangential flow filtration.Short-interference RNAs: becoming medicines.Journey to the Center of the Cell: Current Nanocarrier Design Strategies Targeting Biopharmaceuticals to the Cytoplasm and Nucleus Reductively Responsive Hydrogel Nanoparticles with Uniform Size, Shape, and Tunable Composition for Systemic siRNA Delivery in Vivo.Towards the elimination and eradication of hepatitis B.Pharmacokinetic Behaviors of Intravenously Administered siRNA in Glandular Tissues.An Effective Molecular Target Site in Hepatitis B Virus S Gene for Cas9 Cleavage and Mutational Inactivation The delivery of therapeutic oligonucleotides A Tat-conjugated Peptide Nucleic Acid Tat-PNA-DR Inhibits Hepatitis B Virus Replication In Vitro and In Vivo by Targeting LTR Direct Repeats of HBV RNA.A pliable electroporation patch (ep-Patch) for efficient delivery of nucleic acid molecules into animal tissues with irregular surface shapes.An efficient antiviral strategy for targeting hepatitis B virus genome using transcription activator-like effector nucleases.In vitro and in vivo efficacy of SYL040012, a novel siRNA compound for treatment of glaucoma.Phase I clinical trial of SYL040012, a small interfering RNA targeting β-adrenergic receptor 2, for lowering intraocular pressure.

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P2860

Hepatocyte-targeted RNAi therapeutics for the treatment of chronic hepatitis B virus infection

http://www.wikidata.org/entity/Q36883851

description

2013 nî lūn-bûn

@nan

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

@zh

2013年论文

@zh-cn

name

Hepatocyte-targeted RNAi thera ...... ic hepatitis B virus infection

@en

type

label

Hepatocyte-targeted RNAi thera ...... ic hepatitis B virus infection

@en

prefLabel

Hepatocyte-targeted RNAi thera ...... ic hepatitis B virus infection

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P1433

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P1433

Molecular Therapy

P1476

Hepatocyte-targeted RNAi thera ...... ic hepatitis B virus infection

@en

P2093

Alan McLachlan

http://www.w3.org/2001/XMLSchema#string

Christine I Wooddell

http://www.w3.org/2001/XMLSchema#string

Claudia E Oropeza

http://www.w3.org/2001/XMLSchema#string

Darren H Wakefield

http://www.w3.org/2001/XMLSchema#string

David B Rozema

http://www.w3.org/2001/XMLSchema#string

David L Lewis

http://www.w3.org/2001/XMLSchema#string

Holly L Hamilton

http://www.w3.org/2001/XMLSchema#string

Ingo Roehl

http://www.w3.org/2001/XMLSchema#string

Jason J Klein

http://www.w3.org/2001/XMLSchema#string

Jochen Deckert

http://www.w3.org/2001/XMLSchema#string

P2860

Hepatitis B virus replication

Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Hepatitis B virus nucleocapsid particles do not cross the hepatocyte nuclear membrane in transgenic mice

Argonaute proteins are key determinants of RNAi efficacy, toxicity, and persistence in the adult mouse liver

Clearance of hepatitis B virus from the liver of transgenic mice by short hairpin RNAs

Glyceraldehyde-3-phosphate dehydrogenase mRNA is a major interleukin 2-induced transcript in a cloned T-helper lymphocyte.

High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA.

Nucleotide sequence of the hepatitis B virus genome (subtype ayw) cloned in E. coli.

P304

973-985

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P31

scholarly article

P356

10.1038/MT.2013.31

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P433

5

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P478

21

http://www.w3.org/2001/XMLSchema#string

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Hans-Peter Vornlocher

P577

2013-02-26T00:00:00Z

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235729153

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23439496

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3666629

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