ATR Kinase Inhibition Protects Non-cycling Cells from the Lethal Effects of DNA Damage and Transcription Stress.
about
Bringing It All Together: Coupling Excision Repair to the DNA Damage Checkpoint.DNA damage-induced ATM- and Rad-3-related (ATR) kinase activation in non-replicating cells is regulated by the XPB subunit of transcription factor IIH (TFIIH).Pharmacologic ATM but not ATR kinase inhibition abrogates p21-dependent G1 arrest and promotes gastrointestinal syndrome after total body irradiation.Impact of Age and Insulin-Like Growth Factor-1 on DNA Damage Responses in UV-Irradiated Human Skin.PostExcision Events in Human Nucleotide Excision Repair.ATR maintains chromosomal integrity during postnatal cerebellar neurogenesis and is required for medulloblastoma formation.Reevaluation of ATR signaling in primary resting chronic lymphocytic leukemia cells: evidence for pro-survival or pro-apoptotic function.Insulin-like Growth Factor 1 Receptor Signaling Is Required for Optimal ATR-CHK1 Kinase Signaling in Ultraviolet B (UVB)-irradiated Human Keratinocytes.A New Way to Treat Brain Tumors: Targeting Proteins Coded by Microcephaly Genes?: Brain tumors and microcephaly arise from opposing derangements regulating progenitor growth. Drivers of microcephaly could be attractive brain tumor targets.A novel role for ATR/Rad3 in G1 phase.Roles of UVA radiation and DNA damage responses in melanoma pathogenesis.
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P2860
ATR Kinase Inhibition Protects Non-cycling Cells from the Lethal Effects of DNA Damage and Transcription Stress.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
ATR Kinase Inhibition Protects ...... mage and Transcription Stress.
@en
type
label
ATR Kinase Inhibition Protects ...... mage and Transcription Stress.
@en
prefLabel
ATR Kinase Inhibition Protects ...... mage and Transcription Stress.
@en
P2860
P356
P1476
ATR Kinase Inhibition Protects ...... mage and Transcription Stress.
@en
P2093
Michael G Kemp
P2860
P304
P356
10.1074/JBC.M116.719740
P407
P50
P577
2016-03-03T00:00:00Z