Serine 129 phosphorylation of membrane-associated α-synuclein modulates dopamine transporter function in a G protein-coupled receptor kinase-dependent manner.
about
Features of alpha-synuclein that could explain the progression and irreversibility of Parkinson's diseaseCerebrospinal fluid α-synuclein predicts cognitive decline in Parkinson disease progression in the DATATOP cohort.Post translational changes to α-synuclein control iron and dopamine trafficking; a concept for neuron vulnerability in Parkinson's disease.Mechanisms underlying extensive Ser129-phosphorylation in α-synuclein aggregates.Lys-63-linked ubiquitination by E3 ubiquitin ligase Nedd4-1 facilitates endosomal sequestration of internalized α-synuclein.Novel antibodies to phosphorylated α-synuclein serine 129 and NFL serine 473 demonstrate the close molecular homology of these epitopesAge-dependent dopamine transporter dysfunction and Serine129 phospho-α-synuclein overload in G2019S LRRK2 mice.Protein phosphorylation in neurodegeneration: friend or foe?A new role for α-synuclein in Parkinson's disease: Alteration of ER-mitochondrial communication.Implication of Alpha-Synuclein Phosphorylation at S129 in Synucleinopathies: What Have We Learned in the Last Decade?Sensitive western blotting for detection of endogenous Ser129-phosphorylated α-synuclein in intracellular and extracellular spacesDual role of GRK5 in cancer development and progression.Alpha-synuclein modulates dopamine neurotransmission.Exogenous Alpha-Synuclein Alters Pre- and Post-Synaptic Activity by Fragmenting Lipid Rafts.Influence of 6-Hydroxydopamine Toxicity on α-Synuclein Phosphorylation, Resting Vesicle Expression, and Vesicular Dopamine Release.Dopamine Transporter/α-Synuclein Complexes Are Altered in the Post Mortem Caudate Putamen of Parkinson's Disease: An In Situ Proximity Ligation Assay Study.The Challenge of the Pathogenesis of Parkinson's Disease: Is Autoimmunity the Culprit?
P2860
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P2860
Serine 129 phosphorylation of membrane-associated α-synuclein modulates dopamine transporter function in a G protein-coupled receptor kinase-dependent manner.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Serine 129 phosphorylation of ...... eptor kinase-dependent manner.
@en
type
label
Serine 129 phosphorylation of ...... eptor kinase-dependent manner.
@en
prefLabel
Serine 129 phosphorylation of ...... eptor kinase-dependent manner.
@en
P2093
P2860
P356
P1476
Serine 129 phosphorylation of ...... eptor kinase-dependent manner.
@en
P2093
Asuka Sasaki
Hiroyasu Sato
Shigeki Arawaka
Shingo Koyama
Susumu Hara
Takeo Kato
Youhei Machiya
P2860
P304
1649-60, S1-3
P356
10.1091/MBC.E12-12-0903
P577
2013-04-10T00:00:00Z