Analysis of the complete nucleotide sequence of the picornavirus Theiler's murine encephalomyelitis virus indicates that it is closely related to cardioviruses
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Leader (L) and L* proteins of Theiler's murine encephalomyelitis virus (TMEV) and their regulation of the virus' biological activitiesTheiler's virus infection: a model for multiple sclerosisViral cysteine proteases are homologous to the trypsin-like family of serine proteases: structural and functional implicationsThree-dimensional structure of Theiler murine encephalomyelitis virus (BeAn strain)The encephalomyocarditis virusThree-dimensional structure of Theiler virus.Three-dimensional model of the capsid proteins of two biologically different Theiler virus strains: clustering of amino acid difference identifies possible locations of immunogenic sites on the virionNeurovirulence determinants of genetically engineered Theiler virusesAn attenuated variant of the GDVII strain of Theiler's virus does not persist and does not infect the white matter of the central nervous systemDirect comparison of demyelinating disease induced by the Daniel's strain and BeAn strain of Theiler's murine encephalomyelitis virus.The neurovirulence of the DA and GDVII strains of Theiler's virus correlates with their ability To infect cultured neuronsSialylation of the host receptor may modulate entry of demyelinating persistent Theiler's virus.L* protein of Theiler's murine encephalomyelitis virus is required for virus growth in a murine macrophage-like cell line.The GDVII strain of Theiler's virus spreads via axonal transport.High numbers of viral RNA copies in the central nervous system of mice during persistent infection with Theiler's virus.CD28 costimulatory blockade exacerbates disease severity and accelerates epitope spreading in a virus-induced autoimmune disease.A single base deletion in the 5' noncoding region of Theiler's virus attenuates neurovirulenceInterleukin-6 (IL-6) and IL-17 synergistically promote viral persistence by inhibiting cellular apoptosis and cytotoxic T cell functionA spontaneous low-pathogenic variant of Theiler's virus contains an amino acid substitution within the predominant VP1(233-250) T-cell epitope.Capsid-specific cytotoxic T lymphocytes recognize three distinct H-2D(b)-restricted regions of the BeAn strain of Theiler's virus and exhibit different cytokine profilesDifferences in avidity and epitope recognition of CD8(+) T cells infiltrating the central nervous systems of SJL/J mice infected with BeAn and DA strains of Theiler's murine encephalomyelitis virusBinding interactions between the encephalomyocarditis virus leader and protein 2A.Immunoregulation of a viral model of multiple sclerosis using the synthetic cannabinoid R+WIN55,212Conserved tertiary structural elements in the 5' nontranslated region of cardiovirus, aphthovirus and hepatitis A virus RNAs.Involvement of cardiovirus leader in host cell-restricted virus expression.Melanoma differentiation-associated gene 5 is critical for protection against Theiler's virus-induced demyelinating disease.Injection of the sciatic nerve with TMEV: a new model for peripheral nerve demyelination.The immunodominant CD8+ T cell epitope region of Theiler's virus in resistant C57BL/6 mice is critical for anti-viral immune responses, viral persistence, and binding to the host cells.TLR3 signaling is either protective or pathogenic for the development of Theiler's virus-induced demyelinating disease depending on the time of viral infectionThe leader polypeptide of Theiler's virus is essential for neurovirulence but not for virus growth in BHK cells.The neurovirulent GDVII strain of Theiler's virus can replicate in glial cells.Role of VP2 amino acid 141 in tropism of Theiler's virus within the central nervous system.Major linear antibody epitopes and capsid proteins differentially induce protective immunity against Theiler's virus-induced demyelinating disease.Relationships among the positive strand and double-strand RNA viruses as viewed through their RNA-dependent RNA polymerases.Immunization with structural and non-structural proteins of Theiler's murine encephalomyelitis virus alters demyelinating diseaseIL-1 signal affects both protection and pathogenesis of virus-induced chronic CNS demyelinating disease.Alteration of amino acid 101 within capsid protein VP-1 changes the pathogenicity of Theiler's murine encephalomyelitis virus.Protein 2A is not required for Theiler's virus replication.Importance of amino acid 101 within capsid protein VP1 for modulation of Theiler's virus-induced disease.Analysis of antibody responses to predominant linear epitopes of Theiler's murine encephalomyelitis virus.
P2860
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P2860
Analysis of the complete nucleotide sequence of the picornavirus Theiler's murine encephalomyelitis virus indicates that it is closely related to cardioviruses
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
1987年论文
@zh
1987年论文
@zh-cn
name
Analysis of the complete nucle ...... osely related to cardioviruses
@en
type
label
Analysis of the complete nucle ...... osely related to cardioviruses
@en
prefLabel
Analysis of the complete nucle ...... osely related to cardioviruses
@en
P2093
P2860
P1433
P1476
Analysis of the complete nucle ...... osely related to cardioviruses
@en
P2093
P2860
P304
P407
P577
1987-05-01T00:00:00Z