Dramatic Response of BRAF V600E Mutant Papillary Craniopharyngioma to Targeted Therapy.
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ENDOCRINE TUMORS: BRAF V600E mutations in papillary craniopharyngiomaAdamantinomatous and papillary craniopharyngiomas are characterized by distinct epigenomic as well as mutational and transcriptomic profilesOncogenic PI3K mutations are as common as AKT1 and SMO mutations in meningiomaEpCAM (CD326) is differentially expressed in craniopharyngioma subtypes and Rathke's cleft cystsClinical identification of oncogenic drivers and copy number alterations in pituitary tumors.Genetically engineered mouse models of craniopharyngioma: an opportunity for therapy development and understanding of tumor biology.Risk-adapted treatment and follow-up management in childhood-onset craniopharyngioma.MAPK pathway control of stem cell proliferation and differentiation in the embryonic pituitary provides insights into the pathogenesis of papillary craniopharyngioma.Microsurgical removal of craniopharyngioma: endoscopic and transcranial techniques for complication avoidance.Ethical considerations of neuro-oncology trial design in the era of precision medicine.Recent advances in molecular pathology of craniopharyngioma.Distinct patterns of primary and motile cilia in Rathke's cleft cysts and craniopharyngioma subtypes.Recurrent papillary craniopharyngioma with BRAFV600E mutation treated with neoadjuvant-targeted therapy.Development of the CNS TAP tool for the selection of precision medicine therapies in neuro-oncology.Study of β-catenin and BRAF alterations in adamantinomatous and papillary craniopharyngiomas: mutation analysis with immunohistochemical correlation in 54 cases.Adolescents and young adults with brain tumors in the context of molecular advances in neuro-oncology.What's new in pituitary pathology?High-resolution melting and immunohistochemical analysis efficiently detects mutually exclusive genetic alterations of adamantinomatous and papillary craniopharyngiomas.Adamantinomatous craniopharyngioma and xanthomatous lesions of the sella.Hypothalamic involvement in craniopharyngioma-Implications for surgical, radiooncological, and molecularly targeted treatment strategies.Dabrafenib and trametinib in BRAFV600E mutated glioma.BRAF-V600E mutant papillary craniopharyngioma dramatically responds to combination BRAF and MEK inhibitors.Clinical and radiographic response following targeting of BCAN-NTRK1 fusion in glioneuronal tumor.Rathke's Cleft Cyst as Origin of a Pediatric Papillary Craniopharyngioma.
P2860
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P2860
Dramatic Response of BRAF V600E Mutant Papillary Craniopharyngioma to Targeted Therapy.
description
2015 nî lūn-bûn
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2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
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2015年论文
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name
Dramatic Response of BRAF V600E Mutant Papillary Craniopharyngioma to Targeted Therapy.
@en
type
label
Dramatic Response of BRAF V600E Mutant Papillary Craniopharyngioma to Targeted Therapy.
@en
altLabel
Dramatic Response of BRAF V600E Mutant Papillary Craniopharyngioma to Targeted Therapy
@en
prefLabel
Dramatic Response of BRAF V600E Mutant Papillary Craniopharyngioma to Targeted Therapy.
@en
P2093
P2860
P50
P356
P1476
Dramatic Response of BRAF V600E Mutant Papillary Craniopharyngioma to Targeted Therapy
@en
P2093
Amaro Taylor-Weiner
David J Panka
David N Louis
Dennie T Frederick
Fred G Barker
Ganesh M Shankar
Ian F Dunn
Javier M Romero
Malak Abedalthagafi
P2860
P304
P356
10.1093/JNCI/DJV310
P407
P577
2015-10-23T00:00:00Z