Preferential expression of the c-fps protein in chicken macrophages and granulocytic cells.
about
Identification of a human gene (HCK) that encodes a protein-tyrosine kinase and is expressed in hemopoietic cellsMolecular cloning, expression, and chromosomal localization of the gene encoding a human myeloid membrane antigen (gp150)The Fes protein-tyrosine kinase phosphorylates a subset of macrophage proteins that are involved in cell adhesion and cell-cell signalingRole of c-Fes in normal and neoplastic hematopoiesis.Enzymatic activation of Fujinami sarcoma virus gag-fps transforming proteins by autophosphorylation at tyrosine.Enhanced endotoxin sensitivity in fps/fes-null mice with minimal defects in hematopoietic homeostasis.Activated Fes protein tyrosine kinase induces terminal macrophage differentiation of myeloid progenitors (U937 cells) and activation of the transcription factor PU.1.Antisense strategies to characterize the role of genes and oncogenes involved in myeloid differentiation.Characterization of human c-fes/fps reveals a new transcription unit (fur) in the immediately upstream region of the proto-oncogene.Functional specificity of cytoplasmic and transmembrane tyrosine kinases: identification of 130- and 75-kilodalton substrates of c-fps/fes tyrosine kinase in macrophages.The Fps/Fes protein-tyrosine kinase promotes angiogenesis in transgenic miceMyeloid expression of the human c-fps/fes proto-oncogene in transgenic mice.The human c-fps/fes gene product expressed ectopically in rat fibroblasts is nontransforming and has restrained protein-tyrosine kinase activity.A major site of tyrosine phosphorylation within the SH2 domain of Fujinami sarcoma virus P130gag-fps is not required for protein-tyrosine kinase activity or transforming potential.Antipeptide antiserum identifies a widely distributed cellular tyrosine kinase related to but distinct from the c-fps/fes-encoded protein.Oncogene expression in myelopoiesis.The myeloid-cell-specific c-fes promoter is regulated by Sp1, PU.1, and a novel transcription factor.Structure of the feline c-fes/fps proto-oncogene: genesis of a retroviral oncogene.Fes tyrosine kinase promotes survival and terminal granulocyte differentiation of factor-dependent myeloid progenitors (32D) and activates lineage-specific transcription factors.The structure of the human c-fes/fps proto-oncogene.Inhibition of c-fes expression by an antisense oligomer causes apoptosis of HL60 cells induced to granulocytic differentiation.
P2860
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P2860
Preferential expression of the c-fps protein in chicken macrophages and granulocytic cells.
description
1985 nî lūn-bûn
@nan
1985年の論文
@ja
1985年論文
@yue
1985年論文
@zh-hant
1985年論文
@zh-hk
1985年論文
@zh-mo
1985年論文
@zh-tw
1985年论文
@wuu
1985年论文
@zh
1985年论文
@zh-cn
name
Preferential expression of the ...... phages and granulocytic cells.
@en
type
label
Preferential expression of the ...... phages and granulocytic cells.
@en
prefLabel
Preferential expression of the ...... phages and granulocytic cells.
@en
P2093
P2860
P356
P1476
Preferential expression of the ...... phages and granulocytic cells.
@en
P2093
B Mathey-Prevot
H Hanafusa
P2860
P304
P356
10.1128/MCB.5.5.1067
P407
P577
1985-05-01T00:00:00Z