Connexins and gap junctions in mammary gland development and breast cancer progression.
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Asymmetric expression of connexins between luminal epithelial- and myoepithelial- cells is essential for contractile function of the mammary gland.Connexin's Connection in Breast Cancer Growth and ProgressionPresence of Cx43 in extracellular vesicles reduces the cardiotoxicity of the anti-tumour therapeutic approach with doxorubicinConnexin-43 upregulation in micrometastases and tumor vasculature and its role in tumor cell attachment to pulmonary endotheliumSuicide HSVtk gene delivery by neurotensin-polyplex nanoparticles via the bloodstream and GCV Treatment specifically inhibit the growth of human MDA-MB-231 triple negative breast cancer tumors xenografted in athymic mice.Mammary gland specific knockdown of the physiological surge in Cx26 during lactation retains normal mammary gland development and function.Connexin 43 a check-point component of cell proliferation implicated in a wide range of human testis diseases.Correlations of differentially expressed gap junction connexins Cx26, Cx30, Cx32, Cx43 and Cx46 with breast cancer progression and prognosis.The potential prognostic value of connexin 26 and 46 expression in neoadjuvant-treated breast cancerThe dynamics of connexin expression, degradation and localisation are regulated by gonadotropins during the early stages of in vitro maturation of swine oocytes.Aberrant expression of Cx43 is associated with the peritoneal metastasis of gastric cancer and Cx43-mediated gap junction enhances gastric cancer cell diapedesis from peritoneal mesothelium.Targeting connexin 43 with α-connexin carboxyl-terminal (ACT1) peptide enhances the activity of the targeted inhibitors, tamoxifen and lapatinib, in breast cancer: clinical implication for ACT1The emerging role of the thrombin receptor (PAR-1) in melanoma metastasis--a possible therapeutic target.Loss of Panx1 Impairs Mammary Gland Development at Lactation: Implications for Breast Tumorigenesis.Connexin and pannexin channels in cancer.Biological role of connexin intercellular channels and hemichannelsmiR-381 suppresses C/EBPα-dependent Cx43 expression in breast cancer cells.Directing the assembly of spatially organized multicomponent tissues from the bottom up.The severity of mammary gland developmental defects is linked to the overall functional status of Cx43 as revealed by genetically modified miceCx26 knockout predisposes the mammary gland to primary mammary tumors in a DMBA-induced mouse model of breast cancerKruppel-like factor 4 signals through microRNA-206 to promote tumor initiation and cell survival.A Novel Nectin-mediated Cell Adhesion Apparatus That Is Implicated in Prolactin Receptor Signaling for Mammary Gland Development.Polarity proteins as regulators of cell junction complexes: implications for breast cancer.Expressing connexin 43 in breast cancer cells reduces their metastasis to lungs.Antiproliferative Action of Conjugated Linoleic Acid on Human MCF-7 Breast Cancer Cells Mediated by Enhancement of Gap Junctional Intercellular Communication through Inactivation of NF- κ B.Influence of gap junction intercellular communication composed of connexin 43 on the antineoplastic effect of adriamycin in breast cancer cells.Gap junctions and connexins as therapeutic targets in cancer.Transcriptional control of melanoma metastasis: the importance of the tumor microenvironment.Connexins and the gap in context.The role of connexins in prostate cancer promotion and progression.Cardiac to cancer: connecting connexins to clinical opportunity.Connexins: junctional and non-junctional modulators of proliferation.Up-regulation of connexin-43 expression in bone marrow mesenchymal stem cells plays a crucial role in adhesion and migration of multiple myeloma cells.Low-grade and high-grade mammary carcinomas in WAP-T transgenic mice are independent entities distinguished by Met expression.Connexin 43 in the development and progression of breast cancer: What's the connection? (Review).Overexpression of protease-activated receptor-1 contributes to melanoma metastasis via regulation of connexin 43.Gap Junction Enhancer Potentiates Cytotoxicity of Cisplatin in Breast Cancer Cells.Effect and mechanism of the metastasis suppressor gene BRMS1 on the migration of breast cancer cells.Retinoic acid regulates gap junction intercellular communication in human endometrial stromal cells through modulation of the phosphorylation status of connexin 43.Higher susceptibility of spontaneous and NNK-induced lung neoplasms in connexin 43 deficient CD1 × AJ F1 mice: paradoxical expression of connexin 43 during lung carcinogenesis.
P2860
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P2860
Connexins and gap junctions in mammary gland development and breast cancer progression.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Connexins and gap junctions in mammary gland development and breast cancer progression.
@en
type
label
Connexins and gap junctions in mammary gland development and breast cancer progression.
@en
prefLabel
Connexins and gap junctions in mammary gland development and breast cancer progression.
@en
P1476
Connexins and gap junctions in mammary gland development and breast cancer progression.
@en
P2093
Elizabeth McLachlan
P2888
P304
P356
10.1007/S00232-007-9052-X
P50
P577
2007-07-28T00:00:00Z