The Yin and Yang of interleukin-21 in allergy, autoimmunity and cancer. - Wikidata - awgldk - TriplyDB

The Yin and Yang of interleukin-21 in allergy, autoimmunity and cancer.

The Yin and Yang of interleukin-21 in allergy, autoimmunity and cancer.

http://www.wikidata.org/entity/Q36897846

about

Th17 cells in autoimmune and infectious diseases Genetic Factors in Systemic Lupus Erythematosus: Contribution to Disease Phenotype Inflammatory cytokines in systemic lupus erythematosus Inhibition Role of Atherogenic Diet on Ethyl Carbamate Induced Lung Tumorigenesis in C57BL/6J Mice.Interleukin-21: a new mediator of inflammation in systemic lupus erythematosus.Interleukins and interleukin receptors in rheumatoid arthritis: Research, diagnostics and clinical implications.Immune activation is associated with CD8 T cell interleukin-21 production in HIV-1-infected individuals.Complementarity-determining region 3 size spectratypes of T cell receptor beta chains in CD8+ T cells following antiviral treatment of chronic hepatitis B Exclusion of IL-21 in the pathogenesis of OVA-induced asthma in mice.Plasma cells negatively regulate the follicular helper T cell program IL-21 is required for optimal antibody production and T cell responses during chronic Toxoplasma gondii infection.Abrogation of donor T-cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVL Involvement of interleukin-21 in the regulation of colitis-associated colon cancer.Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus.Fecal stream diversion and mucosal cytokine levels in collagenous colitis: A case report.Impact of interleukin-21 in the pathogenesis of primary Sjögren's syndrome: increased serum levels of interleukin-21 and its expression in the labial salivary glands.Suboptimal immune reconstitution in vertically HIV infected children: a view on how HIV replication and timing of HAART initiation can impact on T and B-cell compartment Evaluation of Chosen Cytokine Levels among Patients with Herpes Zoster as Ability to Provide Immune Response Interleukin-21 promotes osteoclastogenesis in RAW264.7 cells through the PI3K/AKT signaling pathway independently of RANKL IL-21 Promotes Pulmonary Fibrosis through the Induction of Profibrotic CD8+ T Cells.Elevated expression of interleukin-21 and its correlation to T-cell subpopulation in patients with ulcerative colitis.Baseline blood immunological profiling differentiates between Her2-breast cancer molecular subtypes: implications for immunomediated mechanisms of treatment response.Elevated Serum Levels of IL-21 in Kawasaki Disease.IL-21 polymorphisms rs907715 and rs2221903 are associated with decreased non-small cell lung cancer susceptibility Nuclear orphan receptor NR2F6 directly antagonizes NFAT and RORγt binding to the Il17a promoter.Th-17 regulatory cytokines inhibit corticosteroid induced airway structural cells apoptosis.Quiescent and Active Tear Protein Profiles to Predict Vernal Keratoconjunctivitis Reactivation A regulatory effect of IL-21 on T follicular helper-like cell and B cell in rheumatoid arthritis.T Cell-Associated Cytokines in the Pathogenesis of Sjögren's Syndrome Phenotypic and functional characteristics of IL-21-expressing CD8(+) T cells in human nasal polyps.Testing for the association of the KIAA1109/Tenr/IL2/IL21 gene region with rheumatoid arthritis in a European family-based study Neuroinflammation and brain functional disconnection in Alzheimer's disease.The biological and clinical importance of the 'new generation' cytokines in rheumatic diseases Interleukin-21 triggers effector cell responses in the gut.Targeting interleukin-21 in rheumatoid arthritis.Interleukin-21 as a potential therapeutic target for systemic lupus erythematosus.Targeting interleukin-21 in inflammatory diseases.Pivotal roles of the interleukin-23/T helper 17 cell axis in hepatitis B.IL-21 as a therapeutic target in inflammatory disorders.Cytokine-Mediated Immunopathogenesis of Hepatitis B Virus Infections.

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The Yin and Yang of interleukin-21 in allergy, autoimmunity and cancer.

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2008 nî lūn-bûn

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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J.COI.2008.02.004

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Current Opinion in Immunology

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The Yin and Yang of interleukin-21 in allergy, autoimmunity and cancer.

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Rosanne Spolski

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Warren J Leonard

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P2860

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function

Interleukin-21 receptor gene induction in human T cells is mediated by T-cell receptor-induced Sp1 activity.

Interleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cells

Cloning of a type I cytokine receptor most related to the IL-2 receptor beta chain

Differential effects of IL-21 and IL-15 on perforin expression, lysosomal degranulation, and proliferation in CD8 T cells of patients with human immunodeficiency virus-1 (HIV)

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

A critical role for IL-21 in regulating immunoglobulin production

Essential role of IL-21 in B cell activation, expansion, and plasma cell generation during CD4+ T cell-B cell collaboration

IL-21 administration into the nostril alleviates murine allergic rhinitis

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295-301

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10.1016/J.COI.2008.02.004

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