Granulocytic nuclear differentiation of lamin B receptor-deficient mouse EPRO cells.
about
Induction of a massive endoplasmic reticulum and perinuclear space expansion by expression of lamin B receptor mutants and the related sterol reductases TM7SF2 and DHCR7.An epichromatin epitope: persistence in the cell cycle and conservation in evolutionRequirement for lamin B receptor and its regulation by importin {beta} and phosphorylation in nuclear envelope assembly during mitotic exit.Disruption of the gene encoding 3beta-hydroxysterol Delta-reductase (Tm7sf2) in mice does not impair cholesterol biosynthesis.Lamin B receptor regulates the growth and maturation of myeloid progenitors via its sterol reductase domain: implications for cholesterol biosynthesis in regulating myelopoiesis.Overexpression of Lamin B Receptor Results in Impaired Skin Differentiation.Nuclear mechanics in diseaseLamin B receptor recognizes specific modifications of histone H4 in heterochromatin formation.Mouse neutrophils lacking lamin B-receptor expression exhibit aberrant development and lack critical functional responses.Lamins regulate cell trafficking and lineage maturation of adult human hematopoietic cells.Lamin B receptor: multi-tasking at the nuclear envelope.Dosage effect of zero to three functional LBR-genes in vivo and in vitro.The LINC-less granulocyte nucleus.Cooperative Activity of GABP with PU.1 or C/EBPε Regulates Lamin B Receptor Gene Expression, Implicating Their Roles in Granulocyte Nuclear Maturation.Severe generalized muscular atrophia, nerve optic atrophia, ear problem and disability with Pelger-Huet anomaly.An in vitro model for Pelger-Huët anomaly: stable knockdown of lamin B receptor in HL-60 cells.Coordinated increase of nuclear tension and lamin-A with matrix stiffness outcompetes lamin-B receptor that favors soft tissue phenotypes.
P2860
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P2860
Granulocytic nuclear differentiation of lamin B receptor-deficient mouse EPRO cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Granulocytic nuclear differentiation of lamin B receptor-deficient mouse EPRO cells.
@en
type
label
Granulocytic nuclear differentiation of lamin B receptor-deficient mouse EPRO cells.
@en
prefLabel
Granulocytic nuclear differentiation of lamin B receptor-deficient mouse EPRO cells.
@en
P2093
P2860
P1476
Granulocytic nuclear differentiation of lamin B receptor-deficient mouse EPRO cells.
@en
P2093
Ada L Olins
Donald E Olins
Harald Herrmann
Monika Zwerger
Peter Gaines
P2860
P304
P356
10.1016/J.EXPHEM.2008.03.003
P577
2008-05-20T00:00:00Z